PIMA544593

Podoplanin Recombinant Rabbit Monoclonal Antibody (RM449), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544593-Each-of-1 In Stock ₹ 38,416.44

PIMA544593 - Each of 1

₹ 38,416.44

In Stock

Quantity

1

Base Price: ₹ 38,416.44

GST (18%): ₹ 6,914.959

Total Price: ₹ 45,331.399

Antigen

Podoplanin

Classification

Recombinant Monoclonal

Concentration

10 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

Q86YL7

Gene Symbols

PDPN

Immunogen

Recombinant human Podoplanin protein. Sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM449

Conjugate

Unconjugated

Gene

PDPN

Gene Alias

29kDa cytosolic podoplanin intracellular domain, Aggrus, CTA-520D8.1, E11, E11 antigen epitope, epithelial cell surface transmembrane protein antigen, glycoprotein 36, Glycoprotein 38, glycoprotein, 36-KD, GP36, Gp38, GP40, HT1A-1, hT1alpha-1, hT1alpha-2, lung type I cell membrane associated glycoprotein, lung type-I cell membrane-associated glycoprotein (T1A-2), Ots8, OTS-8, OTTHUMP00000009640, OTTHUMP00000044504, PA2.26, PA2.26 antigen, PDPN, PICD, Podoplanin, PSEC0003, PSEC0025, pulmonary type I alveolar epithelial cell transmembrane differentiation marker, RANDAM-2, RP23-348F1.2, RTI140, RTI40, T1a, T1A2, T1A-2, T1alpha, T1-alpha, TI1A, Transmembrane glycoprotein E11, type I cell 40 kDa protein

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

10630

Content And Storage

-20°C

Isotype

IgG

Related Products

Img

Novus Biologicals

NBP257831

--

Img

Thermo Scientific

PIPA596338

--

Img

Novus Biologicals

NBP233108H

--

Img

Novus Biologicals

NBP258863

--

Img

Novus Biologicals

NBP255465

--

Img

Thermo Scientific

PIPA584793

--

Img

Novus Biologicals

NBP258509

--

Img

Novus Biologicals

NBP192304

--

Description

  • Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight
  • Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs
  • Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells
  • As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes
  • Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential
  • Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue
  • Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells
  • Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC
  • Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm
  • Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA544593

--


Antigen:
Podoplanin

Classification:
Recombinant Monoclonal

Concentration:
10 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q86YL7

Gene Symbols:
PDPN

Immunogen:
Recombinant human Podoplanin protein. Sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM449

Conjugate:
Unconjugated

Gene:
PDPN

Gene Alias:
29kDa cytosolic podoplanin intracellular domain, Aggrus, CTA-520D8.1, E11, E11 antigen epitope, epithelial cell surface transmembrane protein antigen, glycoprotein 36, Glycoprotein 38, glycoprotein, 36-KD, GP36, Gp38, GP40, HT1A-1, hT1alpha-1, hT1alpha-2, lung type I cell membrane associated glycoprotein, lung type-I cell membrane-associated glycoprotein (T1A-2), Ots8, OTS-8, OTTHUMP00000009640, OTTHUMP00000044504, PA2.26, PA2.26 antigen, PDPN, PICD, Podoplanin, PSEC0003, PSEC0025, pulmonary type I alveolar epithelial cell transmembrane differentiation marker, RANDAM-2, RP23-348F1.2, RTI140, RTI40, T1a, T1A2, T1A-2, T1alpha, T1-alpha, TI1A, Transmembrane glycoprotein E11, type I cell 40 kDa protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10630

Content And Storage:
-20°C

Isotype:
IgG

Img

Thermo Scientific

PIMA544594

--


Antigen:
MERTK

Classification:
Recombinant Monoclonal

Concentration:
50 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q60805

Gene Symbols:
Mertk

Immunogen:
Recombinant protein of MerTK extracellular domain. Sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM469

Conjugate:
Unconjugated

Gene:
Mertk

Gene Alias:
c-Eyk, c-mer, c-mer proto-oncogene tyrosine kinase, Eyk, MER, MER proto-oncogene, tyrosine kinase, MER receptor tyrosine kinase, MERTK, MGC133349, nmf12, Nyk, Proto-oncogene c-Mer, proto-oncogene tyrosine-protein kinase MER, rdy, receptor tyrosine kinase MerTK, Receptor tyrosine tinase gene probably the gene for Rdy, retinal dystrophy, RP38, sMER, sMERTK, soluble MER, soluble MERTK, STK kinase, Tyro 12, Tyro12, Tyrosine-protein kinase Mer

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17289

Content And Storage:
-20°C

Isotype:
IgG

Img

Thermo Scientific

PIMA544595

--


Antigen:
AMACR

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q9UHK6

Gene Symbols:
AMACR

Immunogen:
A peptide corresponding to residues in human p504s/AMACR. The immunogen range is a synthetic peptide within amino acids 1-100 of human AMACR.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM349

Conjugate:
Unconjugated

Gene:
AMACR

Gene Alias:
2-arylpropionyl-CoA epimerase, 2-methylacyl-CoA racemase, Alpha-methylacyl-CoA racemase, alpha-methylacyl-Coenzyme A racemase, Amacr, AMACRD, amcr, CBAS4, Da1-8, Macr1, Marc1, OTTHUMP00000219978, OTTHUMP00000219979, RACE, RM

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23600

Content And Storage:
-20°C

Isotype:
IgG

Img

Thermo Scientific

PIMA544596

--


Antigen:
NeuN

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
A6NFN3

Gene Symbols:
RBFOX3

Immunogen:
A peptide corresponding to the N-terminus of human NeuN (Fox3, RBFOX3).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM312

Conjugate:
Unconjugated

Gene:
RBFOX3

Gene Alias:
D11Bwg0517e, FLJ56884, FLJ58356, fox 1 homolog (C. elegans) 3, fox1 homolog C, Fox-1 homolog C, FOX3, FOX-3, FOX3NeuN, hexaribonucleotide binding protein 3, hexaribonucleotide binding protein 3 (HRNBP3), Hexaribonucleotide-binding protein 3, Hrnbp3, NEUN, NeuN antigen, Neuna60, neuronal nuclear antigen A60, neuronal nuclei, Neuronal nuclei antigen, RBFOX3, RFOX3, RGD1560070, RNA binding fox-1 homolog 3, RNA binding protein, RNA binding protein fox-1 homolog 3, RNA binding protein, fox-1 homolog (C. elegans) 3, RNA binding protein, fox-1 homolog 3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
146713

Content And Storage:
-20°C

Isotype:
IgG