PIMA545360

alpha-ENaC Monoclonal Antibody (14E10), PerCP, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545360-Each-of-1 In Stock ₹ 38,758.68

PIMA545360 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

alpha-ENaC

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.

P37089, Q61180

Gene Symbols

SCNN1A

Immunogen

Synthetic peptide from the N-terminal of Rat ENaC alpha (aa. 46-68)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

14E10

Conjugate

PerCP

Gene

SCNN1A

Gene Alias

alpha ENaC-2; alpha-ENaC; Alpha-NaCH; amiloride-sensitive epithelial sodium channel; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha; amiloride-sensitive sodium channel subunit alpha 2; BESC2; ENaC; ENaC alpha; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; FLJ21883; mENaC; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; Renac; SCNEA; SCNN1; Scnn1a; sodium channel epithelial 1 alpha subunit; sodium channel, non voltage gated 1 alpha subunit; sodium channel, nonvoltage-gated 1 alpha; sodium channel, non-voltage-gated 1 alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

20276, 25122

Content And Storage

4° C

Isotype

IgG1

Related Products

Img

Thermo Scientific

PIMA545351

--

Img

Thermo Scientific

PIMA545359

--

Img

Thermo Scientific

PIMA545352

--

Img

Thermo Scientific

PIMA545357

--

Img

Thermo Scientific

PIMA545355

--

Img

Thermo Scientific

PIMA545353

--

Img

Thermo Scientific

PIMA545471

--

Img

Thermo Scientific

PIMA545472

--

Description

  • A 1:1,000 dilution of MA5-45360 was sufficient for detection of ENaC alpha in 15 μg of Mouse whole kidney lysate by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 85kDa
  • Epithelial sodium channels are amiloride-sensitive members of the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels
  • Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region
  • There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein
  • ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance
  • ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure
  • ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel
  • Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel’s syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA545360

--


Antigen:
alpha-ENaC

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P37089, Q61180

Gene Symbols:
SCNN1A

Immunogen:
Synthetic peptide from the N-terminal of Rat ENaC alpha (aa. 46-68)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
14E10

Conjugate:
PerCP

Gene:
SCNN1A

Gene Alias:
alpha ENaC-2; alpha-ENaC; Alpha-NaCH; amiloride-sensitive epithelial sodium channel; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha; amiloride-sensitive sodium channel subunit alpha 2; BESC2; ENaC; ENaC alpha; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; FLJ21883; mENaC; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; Renac; SCNEA; SCNN1; Scnn1a; sodium channel epithelial 1 alpha subunit; sodium channel, non voltage gated 1 alpha subunit; sodium channel, nonvoltage-gated 1 alpha; sodium channel, non-voltage-gated 1 alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20276, 25122

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545364

--


Antigen:
PP5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P53041

Gene Symbols:
Ppp5c

Immunogen:
Full length human PP5 protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
12F7

Conjugate:
APC

Gene:
Ppp5c

Gene Alias:
ANP receptor; AU020526; EGK_10788; FLJ36922; FLJ55954; OTTHUMP00000165834; PP5; PPP5; Ppp5c; PPT; PP-T; protein phosphatase 5 catalytic subunit; protein phosphatase 5, catalytic subunit; protein phosphatase T; Serine/threonine-protein phosphatase 5

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5536

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545365

--


Antigen:
PP5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
P53041

Gene Symbols:
Ppp5c

Immunogen:
Full length human PP5 protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
12F7

Conjugate:
FITC

Gene:
Ppp5c

Gene Alias:
ANP receptor; AU020526; EGK_10788; FLJ36922; FLJ55954; OTTHUMP00000165834; PP5; PPP5; Ppp5c; PPT; PP-T; protein phosphatase 5 catalytic subunit; protein phosphatase 5, catalytic subunit; protein phosphatase T; Serine/threonine-protein phosphatase 5

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5536

Content And Storage:
4° C, store in dark

Isotype:
IgG1

Img

Thermo Scientific

PIMA545367

--


Antigen:
HSP70

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
A5A8V7, O88600, P0CB32, P0DMV8, P0DMV9, P0DMW0, P0DMW1, P14659, P16627, P17156, P17879, P34931, P34932, P34933, P54652, P55063, Q27965, Q27975, Q61316, Q61696, Q6S4N2

Gene Symbols:
HSP70.2, HSPA1A, HSPA1B, Hspa1l, HSPA2, HSPA4

Immunogen:
Human native HSP70 protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Porcine, Rat

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
1H11

Conjugate:
APC

Gene:
HSPA4

Gene Alias:
68 kDa heat shock protein; 70 kda heat shock protein-2; 70 kilodalton heat shock protein; 87A; 87A locus; 87C locus; Bb; CG18743; CG31359; CG31359-PA; CG31366; CG31366-PA; CG31449; CG6489; chaperone; dHSP70; dhsp70Aa; Dmel\CG31359; Dmel\CG31366; Dmel_CG31359; Dmel_CG31366; Dm-hsp70; DmHSP70AA; DMHSP7D1; dnaK-type molecular chaperone HSP70-1; epididymis secretory protein Li 103; Hcp70.1; heat shock 10kDa protein 1-like; heat shock 70; heat shock 70 kD protein 1; heat shock 70 kD protein 2; heat shock 70 kDa protein 1; heat shock 70 kDa protein 1/2; heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A/1B; heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 1-Hom; Heat shock 70 kDa protein 1L; heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 2; Heat shock 70 kDa protein 3; heat shock 70 kDa-like protein 1; heat shock 70kD protein 1A; heat shock 70kD protein 1B; heat shock 70kD protein 1B (mapped); heat shock 70kD protein-like 1; heat shock 70kDa protein 1A; heat shock 70kDa protein 1B; heat shock 70kDa protein 1-like; heat shock cognate 70-kd protein, tandem duplicate 2; Heat shock protein; heat shock protein 1A; heat shock protein 1B; heat shock protein 1-like; heat shock protein 70; heat shock protein 70.1; heat shock protein 70.2; heat shock protein 70-1; Heat shock protein 70-1l; Heat shock protein 70Aa; Heat shock protein 70Ab; Heat shock protein 70Ba; Heat shock protein 70Bb; Heat shock protein 70Bc; heat shock protein cognate 70, testis; heat shock protein family A (Hsp70) member 1 like; heat shock protein family A (Hsp70) member 1A; heat shock protein family A (Hsp70) member 1B; heat shock protein, 70 kDa 1; heat shock protein, 70 kDa 3; heat shock protein-70; heat shock-induced protein; heat shock-related protein hsc70t; heat-shock 70-kilodalton protein 1A; heat-shock 70-kilodalton protein 1B; heat-shock protein 70; Heat-shock-protein-70Aa; Heat-shock-protein-70Bb; HEL S 103; HEL-S-103; hs70; Hsc70t; HSP; Hsp 70; hsp68; Hsp70; Hsp-70; HSP70 1; HSP70 1B; HSP70 2; hsp70 87A; hsp70 87C; hsp70 Aa; HSP70 AceyltK77; hsp70(87A); Hsp70(87C); HSP70.1; HSP70.1/2; HSP70.1/HSP70.2; HSP70.2; Hsp70.3; HSP70-1; HSP70-1/HSP70-2; HSP70-1A; HSP70-1B; HSP70-1L; HSP70-2; Hsp70-3; HSP70-87A7; HSP70-87C1; hsp70a; hsp70A1; Hsp70A7d; Hsp70Aa; Hsp-70Aa; Hsp70Aa-PA; Hsp70Ab; Hsp70B; Hsp70Ba; Hsp70Bb; Hsp70Bbc; Hsp70Bb-PA; Hsp70Bc; HSP70-HOM; HSP70I; HSP70T; HSP72; Hspa1; Hspa1a; HSPA1B; Hspa1l; Hspa2; HSPA4; Hspa70; HSX70; hum70t; inducible heat shock protein 70; LP05203p; LP05233p; LP08776p; Major heat shock 70 kDa protein Aa; Major heat shock 70 kDa protein Ab; Major heat shock 70 kDa protein Ba; Major heat shock 70 kDa protein Bb; Major heat shock 70 kDa protein Bc; Msh5; protein 70; si:ch73-46h18.6; si:dkeyp-69e1.1; Spermatid-specific heat shock protein 70; zgc:174006

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100144518, 100524853, 100621324, 15482, 15511, 15512, 15525, 193740, 24472, 24963, 266759, 281826, 281827, 281828, 282254, 294254, 3303, 3304, 3305, 3306, 3308, 396648, 536558, 540190, 60460

Content And Storage:
4° C

Isotype:
IgG1