PIMA545359
alpha-ENaC Monoclonal Antibody (14E10), FITC, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA545359-Each-of-1 | In Stock | ₹ 38,758.68 |
PIMA545359 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,758.68
GST (18%): ₹ 6,976.562
Total Price: ₹ 45,735.242
Antigen
alpha-ENaC
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4
Gene Accession No.
P37089, Q61180
Gene Symbols
SCNN1A
Immunogen
Synthetic peptide from the N-terminal of Rat ENaC alpha (aa. 46-68)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse, Rat
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
14E10
Conjugate
FITC
Gene
SCNN1A
Gene Alias
alpha ENaC-2; alpha-ENaC; Alpha-NaCH; amiloride-sensitive epithelial sodium channel; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha; amiloride-sensitive sodium channel subunit alpha 2; BESC2; ENaC; ENaC alpha; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; FLJ21883; mENaC; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; Renac; SCNEA; SCNN1; Scnn1a; sodium channel epithelial 1 alpha subunit; sodium channel, non voltage gated 1 alpha subunit; sodium channel, nonvoltage-gated 1 alpha; sodium channel, non-voltage-gated 1 alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
20276, 25122
Content And Storage
4° C, store in dark
Isotype
IgG1
Related Products
Description
- A 1:1,000 dilution of MA5-45359 was sufficient for detection of ENaC alpha in 15 μg of Mouse whole kidney lysate by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 85kDa
- Epithelial sodium channels are amiloride-sensitive members of the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels
- Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region
- There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein
- ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance
- ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure
- ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel
- Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel’s syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).
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Antigen: alpha-ENaC
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4
Gene Accession No.: P37089, Q61180
Gene Symbols: SCNN1A
Immunogen: Synthetic peptide from the N-terminal of Rat ENaC alpha (aa. 46-68)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 14E10
Conjugate: FITC
Gene: SCNN1A
Gene Alias: alpha ENaC-2; alpha-ENaC; Alpha-NaCH; amiloride-sensitive epithelial sodium channel; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha; amiloride-sensitive sodium channel subunit alpha 2; BESC2; ENaC; ENaC alpha; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; FLJ21883; mENaC; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; Renac; SCNEA; SCNN1; Scnn1a; sodium channel epithelial 1 alpha subunit; sodium channel, non voltage gated 1 alpha subunit; sodium channel, nonvoltage-gated 1 alpha; sodium channel, non-voltage-gated 1 alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 20276, 25122
Content And Storage: 4° C, store in dark
Isotype: IgG1
Antigen:
alpha-ENaC
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4
Gene Accession No.:
P37089, Q61180
Gene Symbols:
SCNN1A
Immunogen:
Synthetic peptide from the N-terminal of Rat ENaC alpha (aa. 46-68)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
14E10
Conjugate:
FITC
Gene:
SCNN1A
Gene Alias:
alpha ENaC-2; alpha-ENaC; Alpha-NaCH; amiloride-sensitive epithelial sodium channel; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha; amiloride-sensitive sodium channel subunit alpha 2; BESC2; ENaC; ENaC alpha; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; FLJ21883; mENaC; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; Renac; SCNEA; SCNN1; Scnn1a; sodium channel epithelial 1 alpha subunit; sodium channel, non voltage gated 1 alpha subunit; sodium channel, nonvoltage-gated 1 alpha; sodium channel, non-voltage-gated 1 alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
20276, 25122
Content And Storage:
4° C, store in dark
Isotype:
IgG1
Antigen: alpha-ENaC
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene Accession No.: P37089, Q61180
Gene Symbols: SCNN1A
Immunogen: Synthetic peptide from the N-terminal of Rat ENaC alpha (aa. 46-68)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 14E10
Conjugate: PerCP
Gene: SCNN1A
Gene Alias: alpha ENaC-2; alpha-ENaC; Alpha-NaCH; amiloride-sensitive epithelial sodium channel; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha; amiloride-sensitive sodium channel subunit alpha 2; BESC2; ENaC; ENaC alpha; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; FLJ21883; mENaC; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; Renac; SCNEA; SCNN1; Scnn1a; sodium channel epithelial 1 alpha subunit; sodium channel, non voltage gated 1 alpha subunit; sodium channel, nonvoltage-gated 1 alpha; sodium channel, non-voltage-gated 1 alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 20276, 25122
Content And Storage: 4° C
Isotype: IgG1
Antigen:
alpha-ENaC
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene Accession No.:
P37089, Q61180
Gene Symbols:
SCNN1A
Immunogen:
Synthetic peptide from the N-terminal of Rat ENaC alpha (aa. 46-68)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
14E10
Conjugate:
PerCP
Gene:
SCNN1A
Gene Alias:
alpha ENaC-2; alpha-ENaC; Alpha-NaCH; amiloride-sensitive epithelial sodium channel; amiloride-sensitive epithelial sodium channel alpha subunit; amiloride-sensitive sodium channel subunit alpha; amiloride-sensitive sodium channel subunit alpha 2; BESC2; ENaC; ENaC alpha; ENaCa; ENaCalpha; Epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; FLJ21883; mENaC; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; Renac; SCNEA; SCNN1; Scnn1a; sodium channel epithelial 1 alpha subunit; sodium channel, non voltage gated 1 alpha subunit; sodium channel, nonvoltage-gated 1 alpha; sodium channel, non-voltage-gated 1 alpha subunit; sodium channel, nonvoltage-gated, type I, alpha; sodium channel, nonvoltage-gated, type I, alpha polypeptide
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
20276, 25122
Content And Storage:
4° C
Isotype:
IgG1
Antigen: PP5
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene Accession No.: P53041
Gene Symbols: Ppp5c
Immunogen: Full length human PP5 protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: 12F7
Conjugate: APC
Gene: Ppp5c
Gene Alias: ANP receptor; AU020526; EGK_10788; FLJ36922; FLJ55954; OTTHUMP00000165834; PP5; PPP5; Ppp5c; PPT; PP-T; protein phosphatase 5 catalytic subunit; protein phosphatase 5, catalytic subunit; protein phosphatase T; Serine/threonine-protein phosphatase 5
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 5536
Content And Storage: 4° C
Isotype: IgG1
Antigen:
PP5
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4
Gene Accession No.:
P53041
Gene Symbols:
Ppp5c
Immunogen:
Full length human PP5 protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
12F7
Conjugate:
APC
Gene:
Ppp5c
Gene Alias:
ANP receptor; AU020526; EGK_10788; FLJ36922; FLJ55954; OTTHUMP00000165834; PP5; PPP5; Ppp5c; PPT; PP-T; protein phosphatase 5 catalytic subunit; protein phosphatase 5, catalytic subunit; protein phosphatase T; Serine/threonine-protein phosphatase 5
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5536
Content And Storage:
4° C
Isotype:
IgG1
Antigen: PP5
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: 9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4
Gene Accession No.: P53041
Gene Symbols: Ppp5c
Immunogen: Full length human PP5 protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: 12F7
Conjugate: FITC
Gene: Ppp5c
Gene Alias: ANP receptor; AU020526; EGK_10788; FLJ36922; FLJ55954; OTTHUMP00000165834; PP5; PPP5; Ppp5c; PPT; PP-T; protein phosphatase 5 catalytic subunit; protein phosphatase 5, catalytic subunit; protein phosphatase T; Serine/threonine-protein phosphatase 5
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 5536
Content And Storage: 4° C, store in dark
Isotype: IgG1
Antigen:
PP5
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4
Gene Accession No.:
P53041
Gene Symbols:
Ppp5c
Immunogen:
Full length human PP5 protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
12F7
Conjugate:
FITC
Gene:
Ppp5c
Gene Alias:
ANP receptor; AU020526; EGK_10788; FLJ36922; FLJ55954; OTTHUMP00000165834; PP5; PPP5; Ppp5c; PPT; PP-T; protein phosphatase 5 catalytic subunit; protein phosphatase 5, catalytic subunit; protein phosphatase T; Serine/threonine-protein phosphatase 5
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5536
Content And Storage:
4° C, store in dark
Isotype:
IgG1