PIMA545420

SCN9A Monoclonal Antibody (N68/6), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545420-Each-of-1 In Stock ₹ 38,758.68

PIMA545420 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

SCN9A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.

O08562, Q15858, Q62205

Gene Symbols

SCN9A

Immunogen

Fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Hamster, Human, Mouse, Rat

Form

Liquid

Applications

Microarray, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone

N68/6

Conjugate

FITC

Gene

SCN9A

Gene Alias

ETHA; FEB3B; GEFSP7; hNaN; hNE Na; hNE-Na; HSAN2D; KIAA1356; Kiaa4197; MED; mKIAA4197; NAC1; NAC2; NAC3; Nav1.1; Nav1.2; Nav1.3; Nav1.4; Nav1.5; Nav1.6; Nav1.7; Nav1.8; Nav1.9; NE; NE NA; NENA; NE-NA; neuroendocrine sodium channel; Peripheral sodium channel 1; PN1; SCN1; SCN10A; SCN11A; SCN12A; SCN1A; Scn2a; SCN2A1; SCN2A2; SCN3A; SCN4A; SCN5A; SCN8A; Scn9a; SFNP; SNS2; sodium channel 25; sodium channel protein type 9 subunit alpha; Sodium channel protein type IX subunit alpha; sodium channel, voltage gated, type IX alpha subunit; sodium channel, voltage-gated, type 9, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha; sodium channel, voltage-gated, type IX, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha subunit; sodium voltage-gated channel alpha subunit 9; voltage-gated sodium channel alpha subunit Nav1.7; voltage-gated sodium channel subunit alpha Nav1.7

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100751370, 20274, 6335, 78956

Content And Storage

4° C, store in dark

Isotype

IgG1

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Description

  • 1 μg/mL of MA5-45420 was sufficient for detection of Nav1.7 in 10 μg of HEK-293 cell lysate transiently expressing Nav1.7 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 230kDa
  • No cross-reactivity against other Nav channels
  • Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels
  • Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region
  • There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein
  • ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance
  • ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure
  • ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel
  • Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddels syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).

Compare Similar Items

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Img

Thermo Scientific

PIMA545420

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Antigen:
SCN9A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
O08562, Q15858, Q62205

Gene Symbols:
SCN9A

Immunogen:
Fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
N68/6

Conjugate:
FITC

Gene:
SCN9A

Gene Alias:
ETHA; FEB3B; GEFSP7; hNaN; hNE Na; hNE-Na; HSAN2D; KIAA1356; Kiaa4197; MED; mKIAA4197; NAC1; NAC2; NAC3; Nav1.1; Nav1.2; Nav1.3; Nav1.4; Nav1.5; Nav1.6; Nav1.7; Nav1.8; Nav1.9; NE; NE NA; NENA; NE-NA; neuroendocrine sodium channel; Peripheral sodium channel 1; PN1; SCN1; SCN10A; SCN11A; SCN12A; SCN1A; Scn2a; SCN2A1; SCN2A2; SCN3A; SCN4A; SCN5A; SCN8A; Scn9a; SFNP; SNS2; sodium channel 25; sodium channel protein type 9 subunit alpha; Sodium channel protein type IX subunit alpha; sodium channel, voltage gated, type IX alpha subunit; sodium channel, voltage-gated, type 9, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha; sodium channel, voltage-gated, type IX, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha subunit; sodium voltage-gated channel alpha subunit 9; voltage-gated sodium channel alpha subunit Nav1.7; voltage-gated sodium channel subunit alpha Nav1.7

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100751370, 20274, 6335, 78956

Content And Storage:
4° C, store in dark

Isotype:
IgG1

Img

Thermo Scientific

PIMA545421

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Antigen:
SCN9A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
O08562, Q15858, Q62205

Gene Symbols:
SCN9A

Immunogen:
Fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
N68/6

Conjugate:
PerCP

Gene:
SCN9A

Gene Alias:
ETHA; FEB3B; GEFSP7; hNaN; hNE Na; hNE-Na; HSAN2D; KIAA1356; Kiaa4197; MED; mKIAA4197; NAC1; NAC2; NAC3; Nav1.1; Nav1.2; Nav1.3; Nav1.4; Nav1.5; Nav1.6; Nav1.7; Nav1.8; Nav1.9; NE; NE NA; NENA; NE-NA; neuroendocrine sodium channel; Peripheral sodium channel 1; PN1; SCN1; SCN10A; SCN11A; SCN12A; SCN1A; Scn2a; SCN2A1; SCN2A2; SCN3A; SCN4A; SCN5A; SCN8A; Scn9a; SFNP; SNS2; sodium channel 25; sodium channel protein type 9 subunit alpha; Sodium channel protein type IX subunit alpha; sodium channel, voltage gated, type IX alpha subunit; sodium channel, voltage-gated, type 9, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha; sodium channel, voltage-gated, type IX, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha subunit; sodium voltage-gated channel alpha subunit 9; voltage-gated sodium channel alpha subunit Nav1.7; voltage-gated sodium channel subunit alpha Nav1.7

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100751370, 20274, 6335, 78956

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545422

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Antigen:
SCN9A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
O08562, Q15858, Q62205

Gene Symbols:
SCN9A

Immunogen:
Fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
N68/6

Conjugate:
PE

Gene:
SCN9A

Gene Alias:
ETHA; FEB3B; GEFSP7; hNaN; hNE Na; hNE-Na; HSAN2D; KIAA1356; Kiaa4197; MED; mKIAA4197; NAC1; NAC2; NAC3; Nav1.1; Nav1.2; Nav1.3; Nav1.4; Nav1.5; Nav1.6; Nav1.7; Nav1.8; Nav1.9; NE; NE NA; NENA; NE-NA; neuroendocrine sodium channel; Peripheral sodium channel 1; PN1; SCN1; SCN10A; SCN11A; SCN12A; SCN1A; Scn2a; SCN2A1; SCN2A2; SCN3A; SCN4A; SCN5A; SCN8A; Scn9a; SFNP; SNS2; sodium channel 25; sodium channel protein type 9 subunit alpha; Sodium channel protein type IX subunit alpha; sodium channel, voltage gated, type IX alpha subunit; sodium channel, voltage-gated, type 9, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha; sodium channel, voltage-gated, type IX, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha subunit; sodium voltage-gated channel alpha subunit 9; voltage-gated sodium channel alpha subunit Nav1.7; voltage-gated sodium channel subunit alpha Nav1.7

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100751370, 20274, 6335, 78956

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545424

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Antigen:
TRPM7

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
Q923J1, Q925B3, Q96QT4

Gene Symbols:
Trpm7

Immunogen:
Fusion protein amino acids 1817-1863 (C- terminus) of mouse TrpM7

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot

Clone:
S74

Conjugate:
FITC

Gene:
Trpm7

Gene Alias:
2310022G15Rik; 4833414K03Rik; 5033407O22Rik; ALSPDC; CHAK; CHAK1; Channel kinase 1; Channel-kinase 1; FLJ20117; long transient receptor potential channel 7; long transient receptor potential channel 7 {ECO:0000250; Ltpr7; LTRPC ion channel family member 7; LTRPC7; LTrpC-7; LTrpC7 {ECO:0000250; PubMed:11161216}; RGD:620053}; tr; transient receptor potential cation channel subfamily M member 7; transient receptor potential cation channel subfamily M member 7 {ECO:0000312; transient receptor potential cation channel, subfamily M, member 7; transient receptor potential M7; transient receptor potential-phospholipase C-interacting kinase; transient receptor potential-phospholipase C-interacting kinase {ECO:0000303; transient receptor potential-related protein, ChaK; TRMP7; TRP PLIK; Trpm7; trpm7 {ECO:0000312; TRPPLIK; Trp-plik; TRP-PLIK {ECO:0000303; UniProtKB:Q96QT4}

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
54822, 58800, 679906

Content And Storage:
4° C, store in dark

Isotype:
IgG1