PIMA545843

alpha Synuclein Monoclonal Antibody (3F8), APC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA545843-Each-of-1 In Stock ₹ 38,758.68

PIMA545843 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

alpha Synuclein

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

2.15mM MES, 47.35mM phosphate, potassium phosphate, sodium phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.

O55042, P37377, P37840

Gene Symbols

SNCA

Immunogen

Mouse alpha synuclein aggregate

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

3F8

Conjugate

APC

Gene

SNCA

Gene Alias

Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

20617, 29219, 6622

Content And Storage

4° C

Isotype

IgG1

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Description

  • A 1:1,000 dilution of MA5-45843 was sufficient for detection of Alpha Synuclein in 15 μg of human brain cell lysate by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.∣Binds within the 101-140 aa region of human alpha synuclein, determined using WB and ELISA with corresponding peptides
  • Detects approximately 14 kDa band corresponding to Alpha synuclein.approximately Does not detect truncated alpha Synuclein (aa 1-114) Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein
  • These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking
  • Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways
  • Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease
  • Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease
  • Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene
  • Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA545843

--


Antigen:
alpha Synuclein

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate, potassium phosphate, sodium phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
O55042, P37377, P37840

Gene Symbols:
SNCA

Immunogen:
Mouse alpha synuclein aggregate

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
3F8

Conjugate:
APC

Gene:
SNCA

Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20617, 29219, 6622

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545844

--


Antigen:
alpha Synuclein

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
O55042, P37377, P37840

Gene Symbols:
SNCA

Immunogen:
Mouse alpha synuclein aggregate

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
3F8

Conjugate:
FITC

Gene:
SNCA

Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20617, 29219, 6622

Content And Storage:
4° C, store in dark

Isotype:
IgG1

Img

Thermo Scientific

PIMA545845

--


Antigen:
alpha Synuclein

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
O55042, P37377, P37840

Gene Symbols:
SNCA

Immunogen:
Mouse alpha synuclein aggregate

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
3F8

Conjugate:
PerCP

Gene:
SNCA

Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20617, 29219, 6622

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

PIMA545846

--


Antigen:
alpha Synuclein

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
O55042, P37377, P37840

Gene Symbols:
SNCA

Immunogen:
Mouse alpha synuclein aggregate

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
4F1

Conjugate:
APC

Gene:
SNCA

Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
20617, 29219, 6622

Content And Storage:
4° C

Isotype:
IgG1