PIMA545931

Phospho-alpha Synuclein (Ser129) Recombinant Rabbit Monoclonal Antibody (J18), FITC, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA545931-Each-of-1 In Stock ₹ 41,068.80

PIMA545931 - Each of 1

₹ 41,068.80

In Stock

Quantity

1

Base Price: ₹ 41,068.80

GST (18%): ₹ 7,392.384

Total Price: ₹ 48,461.184

Antigen

Phospho-alpha Synuclein (Ser129)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.

O55042, P37840

Gene Symbols

SNCA

Immunogen

Human alpha synuclein AA 124-134: AYEMP-pS-EEGYQ-Cys

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

Applications

Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

J18

Conjugate

FITC

Gene

SNCA

Gene Alias

Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20617, 6622

Content And Storage

4° C, store in dark

Isotype

IgG

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Description

  • A 1:500 dilution of MA5-45931 was sufficient for detection of Alpha Synuclein pSer129 in 10 μg of Mouse Brain by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.∣Binds to phosphorylated serine 129 on alpha synuclein
  • Does not detect unphosphorylated serine 129 alpha synuclein Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein
  • These proteins are abundant in the brain and play a role in regulating synaptic transmission and membrane trafficking
  • Alpha- and beta-synuclein have been shown to selectively inhibit phospholipase D2, suggesting that they may also be involved in signaling pathways
  • Defects in the SNCA gene, which encodes alpha-synuclein, have been implicated in the pathogenesis of Parkinson's disease
  • Additionally, alpha-synuclein peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease
  • Multiple alternatively spliced transcripts encoding different isoforms have been identified for this gene
  • Diseases associated with SNCA include Parkinson Disease 1, Autosomal Dominant and Dementia, Lewy Body.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA545931

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Antigen:
Phospho-alpha Synuclein (Ser129)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
O55042, P37840

Gene Symbols:
SNCA

Immunogen:
Human alpha synuclein AA 124-134: AYEMP-pS-EEGYQ-Cys

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
J18

Conjugate:
FITC

Gene:
SNCA

Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20617, 6622

Content And Storage:
4° C, store in dark

Isotype:
IgG

Img

Thermo Scientific

PIMA545933

--


Antigen:
Phospho-Tau (Ser202, Thr205)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P10636, P10637

Gene Symbols:
MAPT

Immunogen:
Synthetic peptide of Human Phospho Tau (Ser202/Thr205)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
AH36

Conjugate:
APC

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17762, 4137

Content And Storage:
4° C

Isotype:
IgG

Img

Thermo Scientific

PIMA545934

--


Antigen:
Phospho-Tau (Ser202, Thr205)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
9.1mM sodium bicarbonate, 9.44mM PBS with 123mM ethanolamine, 581mM DMSO and no preservative; pH 7.4

Gene Accession No.:
P10636, P10637

Gene Symbols:
MAPT

Immunogen:
Synthetic peptide of Human Phospho Tau (Ser202/Thr205)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
AH36

Conjugate:
FITC

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17762, 4137

Content And Storage:
4° C, store in dark

Isotype:
IgG

Img

Thermo Scientific

PIMA545935

--


Antigen:
Phospho-Tau (Ser202, Thr205)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
2.15mM MES, 47.35mM phosphate with 1.033mM EDTA and no preservative; pH 7.4

Gene Accession No.:
P10636, P10637

Gene Symbols:
MAPT

Immunogen:
Synthetic peptide of Human Phospho Tau (Ser202/Thr205)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Applications:
Dot Blot, ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
AH36

Conjugate:
PerCP

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17762, 4137

Content And Storage:
4° C

Isotype:
IgG