PIMA546190

p73 delta Monoclonal Antibody (DNp73-1.1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA546190-Each-of-1 In Stock ₹ 31,400.52

PIMA546190 - Each of 1

₹ 31,400.52

In Stock

Quantity

1

Base Price: ₹ 31,400.52

GST (18%): ₹ 5,652.094

Total Price: ₹ 37,052.614

Antigen

p73 delta

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

O15350

Gene Symbols

TP73

Immunogen

KLH-coupled synthetic peptide MLYVGDPARHLATC

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

DNp73-1.1

Conjugate

Unconjugated

Gene

TP73

Gene Alias

deltaNp73; OTTHUMP00000003479; OTTHUMP00000003480; p53-like transcription factor; p53-related protein; P73; RP23-254N4.10; TAp73; TP73; transformation related protein 73; Trp73; Tumor protein p73

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7161

Content And Storage

4° C, do not freeze

Isotype

IgG1

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Description

  • Description p73 was identified as a long-lost cousin of tumor suppressor protein, p53 (4)
  • p73 has high homology with p53 as well as with p63, a gene implicated in the maintenance of epithelial stem cells
  • Significant homology between p53, p63, and p73 (approximately 63% amino acid identity in the DNA-binding domain suggest that they may have overlapping functions in the regulation of gene expression (3)
  • The targeted disruption of p73 gene leads to defects hippocampal dysgenesis, hydrocephalus, chronic inflammation and infections (2)
  • Recently, spilicing variant mRNAs of p73 has been identified in MCF-7, a breast carcinoma cell line
  • These mRNAs code for variant p73 proteins bearing distinct carboxy-terminal structures suggesting that the carboxy-terminal region of p73 may be important for the functions of this protein (1) It was found p73 to be upregulated in a significant fraction of anaplastic thyroid cancers, whereas it was not detectable in normal thyroid epithelial cells nor in papillary or follicular thyroid cancer.

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Img

Thermo Scientific

PIMA546190

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Antigen:
p73 delta

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
O15350

Gene Symbols:
TP73

Immunogen:
KLH-coupled synthetic peptide MLYVGDPARHLATC

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
DNp73-1.1

Conjugate:
Unconjugated

Gene:
TP73

Gene Alias:
deltaNp73; OTTHUMP00000003479; OTTHUMP00000003480; p53-like transcription factor; p53-related protein; P73; RP23-254N4.10; TAp73; TP73; transformation related protein 73; Trp73; Tumor protein p73

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7161

Content And Storage:
4° C, do not freeze

Isotype:
IgG1

Img

Thermo Scientific

PIMA546194

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Antigen:
CEACAM6

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P40199

Gene Symbols:
CEACAM6

Immunogen:
Extracts from human breast carcinoma cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
B6.2

Conjugate:
Unconjugated

Gene:
CEACAM6

Gene Alias:
BGP; BGP-1; carcinoembryonic antigen related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); CD66a; CD66c; CD66d; CD66e; CEA; CEACAM-1; CEACAM-3; CEACAM-5; CEACAM6; CEACAM-6; CEAL; CGM1; Cluster of Differentiation 66c; NCA; Non-specific crossreacting antigen; Normal cross-reacting antigen; pan CEACAM

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4680

Content And Storage:
4° C, do not freeze

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA546196

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Antigen:
NKG2D

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Gene Accession No.:
P26718

Gene Symbols:
Klrk1

Immunogen:
NKL cell line

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Inhibition Assays

Clone:
1D11

Conjugate:
Unconjugated

Gene:
Klrk1

Gene Alias:
CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
22914

Content And Storage:
4° C, do not freeze

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA546197

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Antigen:
CD23

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P06734

Gene Symbols:
FCER2

Immunogen:
EBV-transformed human cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
EBVCS-5

Conjugate:
Unconjugated

Gene:
FCER2

Gene Alias:
BLAST-2; CD23; CD23 antigen; CD23A; CLEC4J; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE receptor II; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide; Fcalpha muR; Fcalpha RII; Fce2; fc-epsilon-RII; FCER2; Fcer2a; FceRII; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; low affinity immunoglobulin epsilon Fc receptor; Low affinity immunoglobulin epsilon Fc receptor membrane-bound form; Low affinity immunoglobulin epsilon Fc receptor soluble form; low-affinity IgE receptor; Ly-42; lymphocyte IgE receptor

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2208

Content And Storage:
4° C, do not freeze

Isotype:
IgG1 κ