PIMA546619
RIP2 Recombinant Rabbit Monoclonal Antibody (JE51-90), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA546619-Each-of-1 | In Stock | ₹ 35,849.64 |
PIMA546619 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,849.64
GST (18%): ₹ 6,452.935
Total Price: ₹ 42,302.575
Antigen
RIP2
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O43353
Gene Symbols
RIPK2
Immunogen
Synthetic peptide within human RIPK2 aa 500-540.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Clone
JE51-90
Conjugate
Unconjugated
Gene
RIPK2
Gene Alias
2210420D18Rik; CARD3; CARD-carrying kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARDIAK; CCK; D4Bwg0615e; EC 2.7.11.1; GIG30; growth-in; growth-inhibiting gene 30; kinase RIPK2; receptor (TNFRSF)-interacting serine-threonine kinase 2; receptor interacting serine/threonine kinase 2; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; receptor-interacting protein 2; receptor-interacting serine/threonine-protein kinase 2; receptor-interacting serine-threonine kinase 2; RICK; RIP 2; RIP2; RIP-2; Ripk2; RIP-like; RIP-like-interacting CLARP kinase; Tyrosine-protein kinase RIPK2; UNQ277/PRO314/PRO34092; WUGSC:H_RG437L15.1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
8767
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive Control: PC-3M cell lysate, 22RV1 cell lysate, RWPE-1 cell lysate
- Subcellular Location: Cytoplasm
- Tissue Specificity: Detected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node.Low tissue specificity
- Sequence Similarities: 82% Mouse/Rat
- RIPK2 is a serine/threonine kinase that is involved in cell activation, proliferation, differentiation, and apoptosis
- Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains
- Contributes to the tyrosine phosphorylation of the guanine exchange factor ARHGEF2 through Src tyrosine kinase leading to NF-kappaB activation by NOD2
- Once recruited, RIPK2 autophosphorylates and undergoes 'Lys-63'-linked polyubiquitination by E3 ubiquitin ligases XIAP, BIRC2 and BIRC3
- The polyubiquitinated protein mediates the recruitment of MAP3K7/TAK1 to IKBKG/NEMO and induces 'Lys-63'-linked polyubiquitination of IKBKG/NEMO and subsequent activation of IKBKB/IKKB
- In turn, NF-kappa-B is released from NF-kappa-B inhibitors and translocates into the nucleus where it activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
- Plays also a role during engagement of the T-cell receptor (TCR) in promoting BCL10 phosphorylation and subsequent NF-kappa-B activation.
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Antigen: RIP2
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: O43353
Gene Symbols: RIPK2
Immunogen: Synthetic peptide within human RIPK2 aa 500-540.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: JE51-90
Conjugate: Unconjugated
Gene: RIPK2
Gene Alias: 2210420D18Rik; CARD3; CARD-carrying kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARDIAK; CCK; D4Bwg0615e; EC 2.7.11.1; GIG30; growth-in; growth-inhibiting gene 30; kinase RIPK2; receptor (TNFRSF)-interacting serine-threonine kinase 2; receptor interacting serine/threonine kinase 2; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; receptor-interacting protein 2; receptor-interacting serine/threonine-protein kinase 2; receptor-interacting serine-threonine kinase 2; RICK; RIP 2; RIP2; RIP-2; Ripk2; RIP-like; RIP-like-interacting CLARP kinase; Tyrosine-protein kinase RIPK2; UNQ277/PRO314/PRO34092; WUGSC:H_RG437L15.1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 8767
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
RIP2
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
O43353
Gene Symbols:
RIPK2
Immunogen:
Synthetic peptide within human RIPK2 aa 500-540.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
JE51-90
Conjugate:
Unconjugated
Gene:
RIPK2
Gene Alias:
2210420D18Rik; CARD3; CARD-carrying kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARDIAK; CCK; D4Bwg0615e; EC 2.7.11.1; GIG30; growth-in; growth-inhibiting gene 30; kinase RIPK2; receptor (TNFRSF)-interacting serine-threonine kinase 2; receptor interacting serine/threonine kinase 2; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; receptor-interacting protein 2; receptor-interacting serine/threonine-protein kinase 2; receptor-interacting serine-threonine kinase 2; RICK; RIP 2; RIP2; RIP-2; Ripk2; RIP-like; RIP-like-interacting CLARP kinase; Tyrosine-protein kinase RIPK2; UNQ277/PRO314/PRO34092; WUGSC:H_RG437L15.1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
8767
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: EZH1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P70351, Q92800
Gene Symbols: EZH1
Immunogen: Synthetic peptide within human EZH1 aa 471-510.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: PS01-09
Conjugate: Unconjugated
Gene: EZH1
Gene Alias: enhancer of zeste 1 polycomb repressive complex 2 subunit; enhancer of zeste homolog 1; enhancer of zeste homolog 1 (Drosophila); Enx2; ENX-2; Ezh1; Histone-lysine N-methyltransferase EZH1; hypothetical protein LOC664754; KIAA0388; KMT6B; si:ch211-250i3.1; zgc:136829
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14055, 2145, 303547
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
EZH1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P70351, Q92800
Gene Symbols:
EZH1
Immunogen:
Synthetic peptide within human EZH1 aa 471-510.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
PS01-09
Conjugate:
Unconjugated
Gene:
EZH1
Gene Alias:
enhancer of zeste 1 polycomb repressive complex 2 subunit; enhancer of zeste homolog 1; enhancer of zeste homolog 1 (Drosophila); Enx2; ENX-2; Ezh1; Histone-lysine N-methyltransferase EZH1; hypothetical protein LOC664754; KIAA0388; KMT6B; si:ch211-250i3.1; zgc:136829
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14055, 2145, 303547
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG
Antigen: Bcl-2
Classification: Recombinant Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.5% BSA and 0.03% Proclin 300
Gene Accession No.: P10415
Gene Symbols: Bcl2
Immunogen: A synthetic peptide corresponding to the N-terminus of the Human Bcl-2.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry
Clone: 204
Conjugate: APC
Gene: Bcl2
Gene Alias: apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 596
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Isotype: IgG
Antigen:
Bcl-2
Classification:
Recombinant Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.5% BSA and 0.03% Proclin 300
Gene Accession No.:
P10415
Gene Symbols:
Bcl2
Immunogen:
A synthetic peptide corresponding to the N-terminus of the Human Bcl-2.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry
Clone:
204
Conjugate:
APC
Gene:
Bcl2
Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
596
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Isotype:
IgG
Antigen: Bcl-2
Classification: Recombinant Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.5% BSA and 0.09% sodium azide
Gene Accession No.: P10415
Gene Symbols: Bcl2
Immunogen: A synthetic peptide corresponding to the N-terminus of the Human Bcl-2.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry
Clone: 204
Conjugate: PerCP
Gene: Bcl2
Gene Alias: apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 596
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Isotype: IgG
Antigen:
Bcl-2
Classification:
Recombinant Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.5% BSA and 0.09% sodium azide
Gene Accession No.:
P10415
Gene Symbols:
Bcl2
Immunogen:
A synthetic peptide corresponding to the N-terminus of the Human Bcl-2.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry
Clone:
204
Conjugate:
PerCP
Gene:
Bcl2
Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
596
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Isotype:
IgG