PIMA546622

Bcl-2 Recombinant Rabbit Monoclonal Antibody (204), PerCP, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA546622-Each-of-1 In Stock ₹ 36,705.24

PIMA546622 - Each of 1

₹ 36,705.24

In Stock

Quantity

1

Base Price: ₹ 36,705.24

GST (18%): ₹ 6,606.943

Total Price: ₹ 43,312.183

Antigen

Bcl-2

Classification

Recombinant Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 0.5% BSA and 0.09% sodium azide

Gene Accession No.

P10415

Gene Symbols

Bcl2

Immunogen

A synthetic peptide corresponding to the N-terminus of the Human Bcl-2.

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry

Clone

204

Conjugate

PerCP

Gene

Bcl2

Gene Alias

apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

596

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

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Description

  • Preparation: This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the N-terminus of the Human BCL2/Bcl-2, and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed
  • Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity
  • Protected from prolonged exposure to light
  • Do not freeze! Sodium azide is toxic to cells and should be disposed of properly
  • Flush with large volumes of water during disposal
  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

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Show Difference

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Thermo Scientific

PIMA546622

--


Antigen:
Bcl-2

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.5% BSA and 0.09% sodium azide

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
A synthetic peptide corresponding to the N-terminus of the Human Bcl-2.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
204

Conjugate:
PerCP

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA546623

--


Antigen:
Bcl-2

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.5% BSA and 0.09% sodium azide

Gene Accession No.:
P10415

Gene Symbols:
Bcl2

Immunogen:
A synthetic peptide corresponding to the N-terminus of the Human Bcl-2.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
204

Conjugate:
FITC

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
596

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA546627

--


Antigen:
VEGF Receptor 2

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.5% BSA and 0.09% sodium azide

Gene Accession No.:
P35968

Gene Symbols:
KDR

Immunogen:
Recombinant protein ecoding Human VEGF Receptor 2 (Met1-Glu764).

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
001

Conjugate:
PE

Gene:
KDR

Gene Alias:
6130401C07; CD309; CD309 antigen; fetal liver kinase 1; fetal liver kinase-1; FLK1; Flk-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); flk-1 type VEGF receptor; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; vascular endotheial growth factor 2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3791

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Img

Thermo Scientific

PIMA546628

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Antigen:
CD137

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.5% BSA and 0.03% Proclin 300

Gene Accession No.:
Q07011

Gene Symbols:
TNFRSF9

Immunogen:
Recombinant protein ecoding Human CD137 (Met1-Gln186).

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry

Clone:
819

Conjugate:
APC

Gene:
TNFRSF9

Gene Alias:
4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3604

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid