PIMA547096
GRK2 Recombinant Rabbit Monoclonal Antibody (HL1562), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547096-Each-of-1 | In Stock | ₹ 38,758.68 |
PIMA547096 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,758.68
GST (18%): ₹ 6,976.562
Total Price: ₹ 45,735.242
Antigen
GRK2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P25098, P26817, Q99MK8
Gene Symbols
GRK2
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human GRK2. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
HL1562
Conjugate
Unconjugated
Gene
GRK2
Gene Alias
ADRBK1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; grk 2; Grk2; GRK-2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
110355, 156, 25238
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- ADRBK1 (GRK2) is a serine/threonine kinase
- Many of the G protein-coupled receptors are known to be phosphorylated by G protein-dependent receptor kinases (GRKs)
- G protein-coupled receptor kinases (GRKs) are important regulators of G protein-coupled receptors(GPCRs)
- GRK2 (83 kDa), one of six members of this family that have been identified, is ubiquitously expressed in mammals
- After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs (e.g., a2-adrenergic receptor) are phosphorylated by GRKs
- Internalization of the GPCRs, regulated by beta-arrestin-1, leads to activation of the Ras - Raf - ERK1&2 signaling pathway
- GRK2 activity is tightly controlled by different mechanisms including phosphorylation by kinases such as PKC, Src and ERK1&2, as well as interaction with various proteins
- ERK phosphorylates and thus inactivates GRK2 on serine 670 in a negative feedback mechanism.
Compare Similar Items
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Antigen: GRK2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P25098, P26817, Q99MK8
Gene Symbols: GRK2
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human GRK2. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: HL1562
Conjugate: Unconjugated
Gene: GRK2
Gene Alias: ADRBK1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; grk 2; Grk2; GRK-2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 110355, 156, 25238
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
GRK2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P25098, P26817, Q99MK8
Gene Symbols:
GRK2
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human GRK2. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
HL1562
Conjugate:
Unconjugated
Gene:
GRK2
Gene Alias:
ADRBK1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; grk 2; Grk2; GRK-2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
110355, 156, 25238
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: ADAM17
Classification: Monoclonal
Concentration: 2 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P78536, Q9Z0F8
Gene Symbols: ADAM17
Immunogen: Recombinant protein encompassing a sequence within the center region of human ADAM17. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: HL1572
Conjugate: Unconjugated
Gene: ADAM17
Gene Alias: a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11491, 6868
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
ADAM17
Classification:
Monoclonal
Concentration:
2 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P78536, Q9Z0F8
Gene Symbols:
ADAM17
Immunogen:
Recombinant protein encompassing a sequence within the center region of human ADAM17. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
HL1572
Conjugate:
Unconjugated
Gene:
ADAM17
Gene Alias:
a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11491, 6868
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: IKK gamma
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O88522, Q9Y6K9
Gene Symbols: Ikbkg
Immunogen: Recombinant protein encompassing a sequence within the center region of human IKK gamma. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: HL1577
Conjugate: Unconjugated
Gene: Ikbkg
Gene Alias: 1110037D23Rik; AI848108; AI851264; AMCBX1; AW124339; FIP3; FIP-3; Fip3p; gikk; I-kappa-B kinase gamma; I-kappa-B kinase subunit gamma; ikB kinase subunit gamma; ikB kinase-associated protein 1; IKBKG; IKK[g]; IKK3; IKKAP1; IKKG; IKK-gamma; IMD33; incontinentia pigmenti; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of kappaB kinase gamma; inhibitor of nuclear factor kappa-B kinase subunit gamma; IP; IP1; IP2; IPD2; mF; mFIP-3; Nemo; NF-kappa B essential modulator; NF-kappa-B essential modifier; NF-kappa-B essential modulator; OTTHUMP00000207079; OTTHUMP00000212188; ZC2HC9
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 16151, 8517
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IKK gamma
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O88522, Q9Y6K9
Gene Symbols:
Ikbkg
Immunogen:
Recombinant protein encompassing a sequence within the center region of human IKK gamma. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
HL1577
Conjugate:
Unconjugated
Gene:
Ikbkg
Gene Alias:
1110037D23Rik; AI848108; AI851264; AMCBX1; AW124339; FIP3; FIP-3; Fip3p; gikk; I-kappa-B kinase gamma; I-kappa-B kinase subunit gamma; ikB kinase subunit gamma; ikB kinase-associated protein 1; IKBKG; IKK[g]; IKK3; IKKAP1; IKKG; IKK-gamma; IMD33; incontinentia pigmenti; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of kappaB kinase gamma; inhibitor of nuclear factor kappa-B kinase subunit gamma; IP; IP1; IP2; IPD2; mF; mFIP-3; Nemo; NF-kappa B essential modulator; NF-kappa-B essential modifier; NF-kappa-B essential modulator; OTTHUMP00000207079; OTTHUMP00000212188; ZC2HC9
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
16151, 8517
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: U2AF2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P26368, P26369
Gene Symbols: U2AF2
Immunogen: Recombinant protein encompassing a sequence within the center region of human U2AF65. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: HL1583
Conjugate: Unconjugated
Gene: U2AF2
Gene Alias: 65kDa; hU2AF(65); hU2AF65; splicing factor U2AF 65 kDa subunit; U2 (RNU2) small nuclear RNA auxiliary factor 2; U2 auxiliary factor 65 kDa subunit; U2 small nuclear ribonucleoprotein auxiliary factor (65kD); U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2; U2 small nuclear ribonucleoprotein auxiliary factor (U2AF), 65 kDa; U2 small nuclear RNA auxiliary factor 2; U2 snRNP auxiliary factor large subunit; U2AF2; U2af65; Unknown (protein for MGC:137461)
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11338, 22185, 308335
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
U2AF2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P26368, P26369
Gene Symbols:
U2AF2
Immunogen:
Recombinant protein encompassing a sequence within the center region of human U2AF65. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
HL1583
Conjugate:
Unconjugated
Gene:
U2AF2
Gene Alias:
65kDa; hU2AF(65); hU2AF65; splicing factor U2AF 65 kDa subunit; U2 (RNU2) small nuclear RNA auxiliary factor 2; U2 auxiliary factor 65 kDa subunit; U2 small nuclear ribonucleoprotein auxiliary factor (65kD); U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2; U2 small nuclear ribonucleoprotein auxiliary factor (U2AF), 65 kDa; U2 small nuclear RNA auxiliary factor 2; U2 snRNP auxiliary factor large subunit; U2AF2; U2af65; Unknown (protein for MGC:137461)
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11338, 22185, 308335
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid