PIMA546938

Glucocorticoid receptor (NR3C1) Recombinant Rabbit Monoclonal Antibody (HL1149), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA546938-Each-of-1 In Stock ₹ 38,758.68

PIMA546938 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

Glucocorticoid receptor (NR3C1)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P04150, P06537

Gene Symbols

Nr3c1

Immunogen

Recombinant protein encompassing a sequence within the center region of human Glucocorticoid Receptor. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

HL1149

Conjugate

Unconjugated

Gene

Nr3c1

Gene Alias

cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

14815, 2908

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Store as concentrated solution
  • Centrifuge briefly prior to opening vial
  • Glucocorticoid Receptor (NR3C1) is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors
  • Glucocorticoid Receptor can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins
  • The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus
  • Glucocorticoid Receptor is expressed in the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart
  • Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined
  • Mutations in the Glucocorticoid Receptor gene are a cause of glucocorticoid resistance, or cortisol, resistance
  • Studies have shown that glucocorticoid receptor (GR) must be associated with a complex of chaperone proteins for ligand activation
  • GR binds to known steroids such as dexamethasone with nanomolar affinity

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA546938

--


Antigen:
Glucocorticoid receptor (NR3C1)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P04150, P06537

Gene Symbols:
Nr3c1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Glucocorticoid Receptor. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
HL1149

Conjugate:
Unconjugated

Gene:
Nr3c1

Gene Alias:
cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14815, 2908

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA546939

--


Antigen:
Glucocorticoid receptor (NR3C1)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P04150, P06536, P06537

Gene Symbols:
Nr3c1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Glucocorticoid Receptor. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
HL1151

Conjugate:
Unconjugated

Gene:
Nr3c1

Gene Alias:
cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14815, 24413, 2908

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA546940

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Antigen:
K-Ras (G12A Mutant)

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Carrier-protein conjugated synthetic peptide surrounding mutant G12A of human K-Ras. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
HL1153

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
ALPS4; C-BAS/HAS; CFC2; C-HA-RAS1; C-H-RAS; c-Ki-ras; c-Ki-ras2; c-K-ras; CMNS; CTLO; HAMSV; HRas proto-oncogene, GTPase; HRAS1; H-RASIDX; Ki-Ras; KRAS; K-Ras; KRAS proto-oncogene, GTPase; KRAS1; KRAS2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NCMS; N-ras; NRAS proto-oncogene, GTPase; NRAS1; NS; NS3; NS6; p21ras; RALD; RASH1; RASK2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA546942

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Antigen:
C-Peptide

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P01308, P01322, P01325

Gene Symbols:
INS, Ins1

Immunogen:
Synthetic peptide corresponding to human c-peptide.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
HL1159

Conjugate:
Unconjugated

Gene:
INS

Gene Alias:
Cpeptide; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2-rs1; insulin; insulin 1; Insulin A chain; Insulin B chain; insulin I; insulin-1; Insulin-1 A chain; Insulin-1 B chain; IRDN; MODY10; preproinsulin; proinsulin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16333, 24505, 3630

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid