PIMA547636

Phospho-SRC (Tyr530) Monoclonal Antibody (M261), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA547636-Each-of-1 In Stock ₹ 44,961.78

PIMA547636 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Phospho-SRC (Tyr530)

Classification

Monoclonal

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P05480, P12931, Q9WUD9

Gene Symbols

SRC

Immunogen

Clone (M261) was generated from a phosphopeptide containing amino acid surrounding Tyr-530 at the C-terminus of human c-Src. This sequence has high homology to the conserved site in rat and mouse c-Src, and is conserved in the c-Src family of kinases.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Western Blot

Clone

M261

Conjugate

Unconjugated

Gene

SRC

Gene Alias

ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogen

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

20779, 6714, 83805

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG1

Description

  • This antibody detects a 60 kDa* protein corresponding to c-Src on SDS-PAGE immunoblots of mouse SYF cells transformed with c-Src and treated with pervanadate
  • This antibody also detects the conserved site in Lck (Tyr-505) in human Jurkat cells treated with pervanadate
  • This antibody may detect several c-Src family members phosphorylated at the conserved site for Tyr-530
  • SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth
  • SRC is involved in the regulation of growth and differentiation of eukaryotic cells
  • SRC associates with the cytoplasmic region of various cell surface receptors to facilitate signal transduction, and is also involved in cytoskeletal organization, cell cycle regulation, and apoptosis
  • In humans, the gene encoding SRC is present on chromosome 20
  • Activity of SRC is regulated by two tyrosine residues (Tyr 416 and Tyr527), and phosphorylation of these two sites have opposing effects
  • Phosphorylation of Tyr416 in the activation loop of the kinase domain upregulates enzyme activity while the phosphorylation of Tyr527 decreases enzyme activity
  • Mutations in the SRC gene could be involved in the malignant progression of colon cancer
  • Two transcript variants encoding the same SRC protein have been found thus far.

Compare Similar Items

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Img

Thermo Scientific

PIMA547636

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Antigen:
Phospho-SRC (Tyr530)

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P05480, P12931, Q9WUD9

Gene Symbols:
SRC

Immunogen:
Clone (M261) was generated from a phosphopeptide containing amino acid surrounding Tyr-530 at the C-terminus of human c-Src. This sequence has high homology to the conserved site in rat and mouse c-Src, and is conserved in the c-Src family of kinases.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M261

Conjugate:
Unconjugated

Gene:
SRC

Gene Alias:
ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogen

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20779, 6714, 83805

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547637

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Antigen:
Phospho-STAT1 (Tyr701)

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P42224, P42225

Gene Symbols:
STAT1

Immunogen:
Clone (M135) was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 701 of human Stat1. This peptide sequence has high homology to the conserved tyrosine site in rat and mouse stat1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M135

Conjugate:
Unconjugated

Gene:
STAT1

Gene Alias:
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20846, 25124, 6772

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547638

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Antigen:
Phospho-delta Catenin (Tyr228)

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
O60716, P30999

Gene Symbols:
CTNND1

Immunogen:
Clone M356 was generated from a phospho-delta1-Catenin (Tyr-228) synthetic peptide containing amino acid residues around tyrosine 228 of human delta1-Catenin. This peptide sequence is highly conserved in rat and mouse delta1-Catenin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
M356

Conjugate:
Unconjugated

Gene:
CTNND1

Gene Alias:
AA409437; AU019353; cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin associated protein), delta 1; catenin (cadherin-associated protein), delta 1; catenin delta 1; catenin delta-1; catenin src; catenin, delta 1; Catns; CTNND; Ctnnd1; hypothetical protein; Kiaa0384; mKIAA0384; p120; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(CAS); p120(ctn); P120CAS; p120-catenin; P120CTN

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12388, 1500, 311163

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

Img

Thermo Scientific

PIMA547639

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Antigen:
Phospho-Caveolin 1 (Tyr14)

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P41350, P49817, Q03135

Gene Symbols:
CAV1

Immunogen:
Clone M283 was generated from a phospho-Caveolin-1 (Tyr-14) synthetic peptide corresponding to amino acids surrounding tyrosine 14 in human Caveolin-1. This sequence has significant homology to the conserved site in rat and mouse Caveolin-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
M283

Conjugate:
Unconjugated

Gene:
CAV1

Gene Alias:
BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12389, 25404, 857

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1