PIMA547695

Protein APC Monoclonal Antibody (KT45), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA547695-Each-of-1 In Stock ₹ 39,272.04

PIMA547695 - Each of 1

₹ 39,272.04

In Stock

Quantity

1

Base Price: ₹ 39,272.04

GST (18%): ₹ 7,068.967

Total Price: ₹ 46,341.007

Antigen

Protein APC

Classification

Monoclonal

Concentration

Lot-Specific

Formulation

PBS with 5mM sodium azide

Gene Accession No.

P25054, P70478, Q61315

Gene Symbols

Apc

Immunogen

Clone KT45 was generated from a recombinant protein containing amino acid residues from the C-terminal region of mouse APC. This sequence is highly conserved in human and rat APC, and has low homology to APC2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

KT45

Conjugate

Unconjugated

Gene

Apc

Gene Alias

adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

11789, 24205, 324

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2a

Description

  • This antibody detects a primarily full length APC at 300 kDa* in human Hct116 cells, mouse brain, and in rat PC12 cells
  • In immunocytochemistry, the antibody detects in APC in clusters at the plasma membrane and at the ends of microtubules
  • This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway
  • It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis
  • Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy
  • Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

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Img

Thermo Scientific

PIMA547695

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Antigen:
Protein APC

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 5mM sodium azide

Gene Accession No.:
P25054, P70478, Q61315

Gene Symbols:
Apc

Immunogen:
Clone KT45 was generated from a recombinant protein containing amino acid residues from the C-terminal region of mouse APC. This sequence is highly conserved in human and rat APC, and has low homology to APC2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
KT45

Conjugate:
Unconjugated

Gene:
Apc

Gene Alias:
adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11789, 24205, 324

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a

Img

Thermo Scientific

PIMA547696

--


Antigen:
Protein APC

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P25054, P70478, Q61315

Gene Symbols:
Apc

Immunogen:
Clone KT44 was generated from a recombinant protein containing amino acid residues from the central region mouse APC. This sequence is highly conserved in human and rat APC, and has low homology to APC2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
KT44

Conjugate:
Unconjugated

Gene:
Apc

Gene Alias:
adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11789, 24205, 324

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a

Img

Thermo Scientific

PIMA547697

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Antigen:
ATM

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
Q13315

Gene Symbols:
ATM

Immunogen:
Clone M361 was generated from a recombinant sequence corresponding to amino acids in the C-terminal region of human ATM.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
M361

Conjugate:
Unconjugated

Gene:
ATM

Gene Alias:
AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; Ataxia telangiectasia gene mutated in human beings; ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; Atm; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
472

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG2b

Img

Thermo Scientific

PIMA547698

--


Antigen:
FBXO32

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
Q91Z62, Q969P5, Q9CPU7

Gene Symbols:
FBXO32

Immunogen:
Clone M314 was generated from a synthetic peptide (coupled to carrier protein) corresponding to amino acids from the N-terminal region of mouse Atrogin. This sequence is highly homologous to human and rat Atrogin (F-box only protein 32).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M314

Conjugate:
Unconjugated

Gene:
FBXO32

Gene Alias:
4833442G10Rik; AI430017; atrogin 1; atrogin1; atrogin-1; atrophy gene 1; F-box only protein 32; F-box protein 32; Fbx32; fbxo25; FBXO32; FLJ32424; Gm20361; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F-box protein; similar to F-box only protein 32 isoform 1; zgc:56479

Host Species:
Rat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114907, 171043, 67731

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
__