PIMA547698

FBXO32 Monoclonal Antibody (M314), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA547698-Each-of-1 In Stock ₹ 44,961.78

PIMA547698 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

FBXO32

Classification

Monoclonal

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

Q91Z62, Q969P5, Q9CPU7

Gene Symbols

FBXO32

Immunogen

Clone M314 was generated from a synthetic peptide (coupled to carrier protein) corresponding to amino acids from the N-terminal region of mouse Atrogin. This sequence is highly homologous to human and rat Atrogin (F-box only protein 32).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Western Blot

Clone

M314

Conjugate

Unconjugated

Gene

FBXO32

Gene Alias

4833442G10Rik; AI430017; atrogin 1; atrogin1; atrogin-1; atrophy gene 1; F-box only protein 32; F-box protein 32; Fbx32; fbxo25; FBXO32; FLJ32424; Gm20361; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F-box protein; similar to F-box only protein 32 isoform 1; zgc:56479

Host Species

Rat

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

114907, 171043, 67731

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Description

  • This antibody detects a full length human recombinant Atrogin 1 on SDS-PAGE immunoblots
  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box
  • The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs, which function in phosphorylation-dependent ubiquitination
  • The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs
  • The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain
  • This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy
  • This protein is thus a potential drug target for the treatment of muscle atrophy
  • Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.

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Img

Thermo Scientific

PIMA547698

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Antigen:
FBXO32

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
Q91Z62, Q969P5, Q9CPU7

Gene Symbols:
FBXO32

Immunogen:
Clone M314 was generated from a synthetic peptide (coupled to carrier protein) corresponding to amino acids from the N-terminal region of mouse Atrogin. This sequence is highly homologous to human and rat Atrogin (F-box only protein 32).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M314

Conjugate:
Unconjugated

Gene:
FBXO32

Gene Alias:
4833442G10Rik; AI430017; atrogin 1; atrogin1; atrogin-1; atrophy gene 1; F-box only protein 32; F-box protein 32; Fbx32; fbxo25; FBXO32; FLJ32424; Gm20361; MAFbx; MGC108443; MGC137646; MGC33610; Muscle atrophy F-box protein; similar to F-box only protein 32 isoform 1; zgc:56479

Host Species:
Rat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114907, 171043, 67731

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Img

Thermo Scientific

PIMA547699

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Antigen:
Caspase 3 p17

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P42574, P55213, P70677

Gene Symbols:
CASP3

Immunogen:
Clone 31A1067 was developed against full-length recombinant human Caspase-3. The antibody recognizes an epitope in the large domain subunit (p17) of Caspase-3, and it will recognize pro Caspase-3 and the p17 cleavage fragment.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
31A1067

Conjugate:
Unconjugated

Gene:
CASP3

Gene Alias:
A830040C14Rik; AC-3; Apopain; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; CC3; Cleaved Caspase 3; Cpp32; CPP-32; CPP32beta; cysteine protease CPP32; IRP; LICE; mLdy; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12367, 25402, 836

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Img

Thermo Scientific

PIMA547700

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Antigen:
Caspase 6

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P55212

Gene Symbols:
Casp6

Immunogen:
Clone (M378) was generated from a peptide containing amino acid residues in the C-terminal region of human Caspase-6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Clone:
M378

Conjugate:
Unconjugated

Gene:
Casp6

Gene Alias:
apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
839

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Img

Thermo Scientific

PIMA547701

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Antigen:
c-Cbl

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P22681, P22682

Gene Symbols:
Cbl

Immunogen:
Clone (M159) was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region of human c-Cbl. This sequence is highly conserved in rat and mouse c-Cbl.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M159

Conjugate:
Unconjugated

Gene:
Cbl

Gene Alias:
4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12402, 500985, 867

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles