PIMA547712
DAAM1 Monoclonal Antibody (5D3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547712-Each-of-1 | In Stock | ₹ 39,272.04 |
PIMA547712 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,272.04
GST (18%): ₹ 7,068.967
Total Price: ₹ 46,341.007
Antigen
DAAM1
Classification
Monoclonal
Concentration
Lot-Specific
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
Q8BPM0, Q9Y4D1
Gene Symbols
DAAM1
Immunogen
Clone 5D3 was generated from a recombinant protein that included amino acid residues from the N-terminal region of human DAAM1. This sequence has less than 50% homology to the N-terminal region of DAAM2.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Clone
5D3
Conjugate
Unconjugated
Gene
DAAM1
Gene Alias
Daam1; Disheveled-associated activator of morphogenesis 1; dishevelled associated activator of morphogenesis 1; I79_021650; KIAA0666
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
208846, 23002, 314212
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG2a
Description
- The antibody detects a 125 kDa* protein corresponding to the apparent molecular mass of DAAM1 on SDS-PAGE immunoblots of human A431, K562, and mouse C2C12 cells
- DAAM1 is a diaphanous-related formin first studied as a novel Disheveled binding protein and shown to be crucial for the planar cell polarity pathway in Xenopus
- DAAM1, like other formins, directs nucleation and elongation of new actin filaments using its conserved formin-homology-2 (FH2) domain
- It is a Rho-regulated formin implicated in neuronal development and regulation of gastrulation
- It was identified as a binding protein of the Wnt receptor-associated protein Disheveled
- It also binds the GTP-bound RhoA and increases its GTP-bound form population in cells
- It exists in an autoinhibited state via intramolecular interactions between its amino-terminal GBD and carboxyl-terminal DAD domains
- Structurally the protein includes a GTPase-binding domain (GBD), a diaphanous inhibitory domain (DID), and a coiled-coil region followed by the FH1, FH2 and C-terminal diaphanous auto-regulatory domain (DAD)
- In humans, the DAAM1 gene is mapped to chromosome 14q23.1.
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Antigen: DAAM1
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q8BPM0, Q9Y4D1
Gene Symbols: DAAM1
Immunogen: Clone 5D3 was generated from a recombinant protein that included amino acid residues from the N-terminal region of human DAAM1. This sequence has less than 50% homology to the N-terminal region of DAAM2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: 5D3
Conjugate: Unconjugated
Gene: DAAM1
Gene Alias: Daam1; Disheveled-associated activator of morphogenesis 1; dishevelled associated activator of morphogenesis 1; I79_021650; KIAA0666
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 208846, 23002, 314212
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG2a
Antigen:
DAAM1
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q8BPM0, Q9Y4D1
Gene Symbols:
DAAM1
Immunogen:
Clone 5D3 was generated from a recombinant protein that included amino acid residues from the N-terminal region of human DAAM1. This sequence has less than 50% homology to the N-terminal region of DAAM2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
5D3
Conjugate:
Unconjugated
Gene:
DAAM1
Gene Alias:
Daam1; Disheveled-associated activator of morphogenesis 1; dishevelled associated activator of morphogenesis 1; I79_021650; KIAA0666
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
208846, 23002, 314212
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG2a
Antigen: EB1/EB2/EB3
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q15555, Q15691, Q3B8Q0, Q5XIT1, Q61166, Q66HR2, Q6PER3, Q8R001, Q9UPY8
Gene Symbols: Mapre1, Mapre2, Mapre3
Immunogen: Clone KT65 was generated from a GST fusion protein containing amino acids from the C-terminal region mouse EB1. This sequence is highly conserved in human and rat EB1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: KT65
Conjugate: Unconjugated
Gene: Mapre2
Gene Alias: APC; Microtubule RP/EB
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100732, 10982, 114764, 13589, 212307, 22919, 22924, 298848, 679221
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG2a
Antigen:
EB1/EB2/EB3
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q15555, Q15691, Q3B8Q0, Q5XIT1, Q61166, Q66HR2, Q6PER3, Q8R001, Q9UPY8
Gene Symbols:
Mapre1, Mapre2, Mapre3
Immunogen:
Clone KT65 was generated from a GST fusion protein containing amino acids from the C-terminal region mouse EB1. This sequence is highly conserved in human and rat EB1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
KT65
Conjugate:
Unconjugated
Gene:
Mapre2
Gene Alias:
APC; Microtubule RP/EB
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100732, 10982, 114764, 13589, 212307, 22919, 22924, 298848, 679221
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG2a
Antigen: MAPRE3
Classification: Monoclonal
Concentration: ∽1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q5XIT1, Q6PER3, Q9UPY8
Gene Symbols: MAPRE3
Immunogen: Clone KT53 was generated from a GST fusion protein containing human EB3. This sequence is highly conserved in rat and mouse EB3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: KT53
Conjugate: Unconjugated
Gene: MAPRE3
Gene Alias: AI790651; APC binding protein; EB1 protein family member 3; EB2; EB3; EBF3; EBF3-S; End-binding protein 3; Mapre3; microtubule associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100732, 22924, 298848
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG2a
Antigen:
MAPRE3
Classification:
Monoclonal
Concentration:
∽1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q5XIT1, Q6PER3, Q9UPY8
Gene Symbols:
MAPRE3
Immunogen:
Clone KT53 was generated from a GST fusion protein containing human EB3. This sequence is highly conserved in rat and mouse EB3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
KT53
Conjugate:
Unconjugated
Gene:
MAPRE3
Gene Alias:
AI790651; APC binding protein; EB1 protein family member 3; EB2; EB3; EBF3; EBF3-S; End-binding protein 3; Mapre3; microtubule associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100732, 22924, 298848
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG2a
Antigen: Fascin
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P85845, Q16658, Q61553
Gene Symbols: FSCN1
Immunogen: Clone (55K2) was generated from full-length human fascin purified from HeLa cells. This sequence has high homology to rat and mouse fascin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: 55K2
Conjugate: Unconjugated
Gene: FSCN1
Gene Alias: 55 kDa actin-bundling protein; 55kDa actin-bundling protein; AI663989; Fan1; fascin; fascin 1; fascin actin-bundling protein 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus); fascin homolog 1, actin-bundling protein; Fascin1; fascin-1; Fscn1; fscn1 {ECO:0000250; HSN; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); singed-like protein; SNL; UniProtKB:Q16658}
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14086, 6624, 683788
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
Fascin
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P85845, Q16658, Q61553
Gene Symbols:
FSCN1
Immunogen:
Clone (55K2) was generated from full-length human fascin purified from HeLa cells. This sequence has high homology to rat and mouse fascin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
55K2
Conjugate:
Unconjugated
Gene:
FSCN1
Gene Alias:
55 kDa actin-bundling protein; 55kDa actin-bundling protein; AI663989; Fan1; fascin; fascin 1; fascin actin-bundling protein 1; Fascin homolog 1; fascin homolog 1, actin bundling protein; fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus); fascin homolog 1, actin-bundling protein; Fascin1; fascin-1; Fscn1; fscn1 {ECO:0000250; HSN; p55; Singed; Singed (Drosophila) like (sea urchin fascin homolog like); singed-like (fascin homolog, sea urchin); singed-like protein; SNL; UniProtKB:Q16658}
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14086, 6624, 683788
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1