PIMA547721

CD61 (Integrin beta 3) Monoclonal Antibody (M581), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA547721-Each-of-1 In Stock ₹ 44,961.78

PIMA547721 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

CD61 (Integrin beta 3)

Classification

Monoclonal

Concentration

0.08 mg/mL

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

O54890, P05106

Gene Symbols

ITGB3

Immunogen

Clone M581 was generated from a recombinant protein containing amino acid residues in the extracellular region of human Integrin beta3. This sequence has high homology with rat and mouse Integrin beta3, and has low homology to other integrin family members.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

M581

Conjugate

Unconjugated

Gene

ITGB3

Gene Alias

antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16416, 29302, 3690

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG1

Description

  • This antibody detects a 100kDa* protein corresponding to the molecular mass of Integrin beta3 on SDS-PAGE immunoblots of human platelets and endothelial cells (HUVEC)
  • CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets and their precursors
  • CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectrin
  • CD61 is a 105 kDa glycoprotein that associates with either the alpha 11b integrin (CD41) or the alpha V integrin (CD51) at the cell surface
  • CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51
  • CD61 is a receptor for fibrinogen, fibronectin, Von Willebrand Factor, vitronectin and thrombospondin
  • The CD61 protein product is composed of an alpha chain and a beta chain
  • A given chain may combine with multiple partners resulting in different integrins
  • CD61 is found along with the alpha IIb chain in platelets
  • Like other integrins, CD61 is known to participate in cell adhesion as well as cell-surface mediated signaling
  • Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.

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Thermo Scientific

PIMA547721

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Antigen:
CD61 (Integrin beta 3)

Classification:
Monoclonal

Concentration:
0.08 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
O54890, P05106

Gene Symbols:
ITGB3

Immunogen:
Clone M581 was generated from a recombinant protein containing amino acid residues in the extracellular region of human Integrin beta3. This sequence has high homology with rat and mouse Integrin beta3, and has low homology to other integrin family members.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
M581

Conjugate:
Unconjugated

Gene:
ITGB3

Gene Alias:
antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16416, 29302, 3690

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

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Thermo Scientific

PIMA547722

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Antigen:
Laminin beta-2/gamma-1

Classification:
Monoclonal

Concentration:
∽1.0 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P11047, P55268

Gene Symbols:
LAMB2, LAMC1

Immunogen:
Clone (M046) was generated from a recombinant human laminin 521 protein that includes a heterotrimer of three subunits laminin alpha5, laminin beta2, and laminin gamma1 subunits.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
M046

Conjugate:
Unconjugated

Gene:
LAMB2

Gene Alias:
AA408497; AW211941; B2e; basement membrane protein; Lama; Lamb2; Lamb-2; Lamc1; Laminin B1s chain; laminin B2 chain; laminin beta 2; laminin beta 2 chain; laminin chain B3; laminin chain beta 2; laminin gamma 1 chain; Laminin S; laminin subunit beta 2; laminin subunit beta-2; laminin subunit gamma 1; laminin subunit gamma-1; laminin, beta 2; laminin, beta 2 (laminin S); laminin, gamma 1; laminin, gamma 1 (formerly LAMB2); laminin-1 subunit gamma; Laminin-10 subunit gamma; laminin-11 subunit beta; Laminin-11 subunit gamma; laminin-14 subunit beta; Laminin-15 subunit beta; laminin-2 subunit gamma; Laminin-3 subunit beta; laminin-3 subunit gamma; Laminin-4 subunit beta; laminin-4 subunit gamma; Laminin-6 subunit gamma; laminin-7 subunit beta; Laminin-7 subunit gamma; laminin-8 subunit gamma; Laminin-9 subunit beta; laminin-9 subunit gamma; LAMS; NPHS5; npht; SLAM; S-LAM beta; S-LAM gamma; S-laminin subunit beta; S-laminin subunit gamma

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3913, 3915

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG2b

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Thermo Scientific

PIMA547723

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Antigen:
MURF1

Classification:
Monoclonal

Concentration:
∽2.0 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
Q38HM4, Q91Z63, Q969Q1

Gene Symbols:
TRIM63

Immunogen:
Clone M316 was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal half of human MuRF1. This peptide sequence is highly conserved in rat and mouse MuRF1, and has 50% homology to MuRF2 (TRIM-55).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Western Blot

Clone:
M316

Conjugate:
Unconjugated

Gene:
TRIM63

Gene Alias:
E3 ubiquitin-protein ligase TRIM63; FLJ32380; IRF; iris ring finger protein; Murf; MURF 1; MuRF1; MuRF-1; MURF2; muscle ring finger protein 1; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; OTTHUMP00000008701; RF1; ring finger protein 28; RING-type E3 ubiquitin transferase TRIM63; RNF 28; RNF28; SMRZ; striated muscle RING zinc finger protein; TRIM 63; Trim63; tripartite motif containing 63; tripartite motif containing 63, E3 ubiquitin protein ligase; tripartite motif protein 63; tripartite motif-containing 63; tripartite motif-containing protein 63

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
140939, 433766, 84676

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1

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Thermo Scientific

PIMA547724

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Antigen:
Neuropilin 1

Classification:
Monoclonal

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
O14786, P97333, Q9QWJ9

Gene Symbols:
NRP1

Immunogen:
Clone M534 was generated from a neuropilin-1 synthetic peptide (coupled to carrier protein) corresponding to amino acids within the a1 CUB domain of human neuropilin-1. This sequence is highly conserved in rat and mouse neuropilin-1, and has low homology to neuropilin-2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Clone:
M534

Conjugate:
Unconjugated

Gene:
NRP1

Gene Alias:
A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
18186, 246331, 8829

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG1