PIMA547835
Basiliximab Chimeric Recombinant Human Monoclonal Antibody (Basiliximab), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547835-Each-of-1 | In Stock | ₹ 44,961.78 |
PIMA547835 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,961.78
GST (18%): ₹ 8,093.12
Total Price: ₹ 53,054.90
Antigen
Basiliximab Chimeric
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Host Species
Human
Purification Method
Affinity chromatography
Regulatory Status
RUO
Target Species
Cynomolgus Monkey, Human, Rhesus Monkey
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (PFA fixed), Inhibition Assays, Western Blot
Clone
Basiliximab
Conjugate
Unconjugated
Gene Alias
CHI621
Immunogen
Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
Quantity
200 μg
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1 κ
Description
- Specificity: Basiliximab recognises the human IL-2R and binds to the epitope (116)ERIYHFV(122) within the extracellular domain of the CD25 subunit-binding is abolished when 2 or more residues within the epitope are mutated
- This epitope overlaps with the interaction site of CD25 and IL-2
- CD25 is found in the high-affinity IL-2R (alpha-Beta-gamma-c)-T cells only express CD25 upon activation
- IL-2 binding to IL-2R on T cells modulates proliferation and differentiation
- A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes
- It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha
- Basiliximab binds with high-affinity to the alpha-subunit (CD25) of the high-affinity IL-2 receptor
- This inhibits IL-2 binding, which inhibits T-cell activation and prevents the body from mounting an immune response against the foreign kidney.
Compare Similar Items
Show Difference
Antigen: Basiliximab Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Cynomolgus Monkey, Human, Rhesus Monkey
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (PFA fixed), Inhibition Assays, Western Blot
Clone: Basiliximab
Conjugate: Unconjugated
Gene Alias: CHI621
Immunogen: Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
Basiliximab Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Cynomolgus Monkey, Human, Rhesus Monkey
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (PFA fixed), Inhibition Assays, Western Blot
Clone:
Basiliximab
Conjugate:
Unconjugated
Gene Alias:
CHI621
Immunogen:
Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ
Antigen: Basiliximab Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Cynomolgus Monkey, Human, Rhesus Monkey
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Inhibition Assays, Western Blot
Clone: Basiliximab
Conjugate: Unconjugated
Gene Alias: CHI621
Immunogen: Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
Basiliximab Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Cynomolgus Monkey, Human, Rhesus Monkey
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Inhibition Assays, Western Blot
Clone:
Basiliximab
Conjugate:
Unconjugated
Gene Alias:
CHI621
Immunogen:
Basiliximab was prepared by immunizing BALB/c mice with CTC 16 cells.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: AFP
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: AF5
Conjugate: Unconjugated
Gene Alias: a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Immunogen: AF5 was prepared by immunizing female BALB/c mice with human amniotic fluid containing AFP, from a pregnancy affected by a neural tube defect, diluted and emulsified in Freund's complete adjuvant.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
AFP
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
AF5
Conjugate:
Unconjugated
Gene Alias:
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Immunogen:
AF5 was prepared by immunizing female BALB/c mice with human amniotic fluid containing AFP, from a pregnancy affected by a neural tube defect, diluted and emulsified in Freund's complete adjuvant.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ
Antigen: AFP Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: AF5
Conjugate: Unconjugated
Gene Alias: a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Immunogen: AF5 was prepared by immunizing female BALB/c mice with human amniotic fluid containing AFP, from a pregnancy affected by a neural tube defect, diluted and emulsified in Freund's complete adjuvant.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
AFP Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
AF5
Conjugate:
Unconjugated
Gene Alias:
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Immunogen:
AF5 was prepared by immunizing female BALB/c mice with human amniotic fluid containing AFP, from a pregnancy affected by a neural tube defect, diluted and emulsified in Freund's complete adjuvant.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ