PIMA547865
Abciximab Recombinant Human Monoclonal Antibody (7E3 (Abciximab)), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547865-Each-of-1 | In Stock | ₹ 44,961.78 |
PIMA547865 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,961.78
GST (18%): ₹ 8,093.12
Total Price: ₹ 53,054.90
Antigen
Abciximab
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Host Species
Human
Purification Method
Protein A
Regulatory Status
RUO
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Inhibition Assays
Clone
7E3 (Abciximab)
Conjugate
Unconjugated
Gene Alias
c7E3
Immunogen
CD41 is the integrin alpha chain 2b forming a fibrinogen receptor in heterodimeric complex with beta 3.
Quantity
200 μg
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1 κ
Related Products
Description
- Specificity: Recognises human CD41
- Abciximab is a Fab fragment of the chimeric human-murine monoclonal antibody 7E3
- Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules
- It also binds to vitronectin (alpha-v-beta-3) receptor found on platelets and vessel wall endothelial and smooth muscle cells
- Abciximab binds to the intact platelet GpiIb/IIIa receptor, which is a member of the integrin family of adhesion receptors and the major platelet surface receptor involved in platelet aggregation
- This binding is thought to involve steric hindrance and/or conformational alterations which block access of large molecules to the receptor rather than direct interaction with the RGD (arginine-glycine-aspartic acid) binding site of GpiIb/IIIa
- By binding to the vitronectin receptor (also known as the alpha-v-beta-3 integrin), abciximab blocks effects mediated by this integrin which include cell adhesion
- Furthermore, abciximab blocks Mac-1 receptor on monocytes and neutrophils thus inhibiting monocyte adhesion.
Compare Similar Items
Show Difference
Antigen: Abciximab
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Human
Purification Method: Protein A
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Inhibition Assays
Clone: 7E3 (Abciximab)
Conjugate: Unconjugated
Gene Alias: c7E3
Immunogen: CD41 is the integrin alpha chain 2b forming a fibrinogen receptor in heterodimeric complex with beta 3.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
Abciximab
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Human
Purification Method:
Protein A
Regulatory Status:
RUO
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Inhibition Assays
Clone:
7E3 (Abciximab)
Conjugate:
Unconjugated
Gene Alias:
c7E3
Immunogen:
CD41 is the integrin alpha chain 2b forming a fibrinogen receptor in heterodimeric complex with beta 3.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ
Antigen: Abciximab Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Inhibition Assays
Clone: 7E3 (Abciximab)
Conjugate: Unconjugated
Gene Alias: c7E3
Immunogen: CD41 is the integrin alpha chain 2b forming a fibrinogen receptor in heterodimeric complex with beta 3.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
Abciximab Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Inhibition Assays
Clone:
7E3 (Abciximab)
Conjugate:
Unconjugated
Gene Alias:
c7E3
Immunogen:
CD41 is the integrin alpha chain 2b forming a fibrinogen receptor in heterodimeric complex with beta 3.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: CD28
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Rat
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry, T-Cell Activation
Clone: JJ316
Conjugate: Unconjugated
Gene Alias: antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Immunogen: Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
CD28
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Rat
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry, T-Cell Activation
Clone:
JJ316
Conjugate:
Unconjugated
Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Immunogen:
Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ
Antigen: CD28 Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Rat
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry, T-Cell Activation
Clone: JJ316
Conjugate: Unconjugated
Gene Alias: antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Immunogen: Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
CD28 Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Rat
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry, T-Cell Activation
Clone:
JJ316
Conjugate:
Unconjugated
Gene Alias:
antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44
Immunogen:
Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ