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PIMA547956

Cardiac Troponin I Chimeric Recombinant Rabbit Monoclonal Antibody (scFv 180), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA547956-Each-of-1 In Stock ₹ 44,961.78

PIMA547956 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Cardiac Troponin I Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P19429

Gene Symbols

TNNI3

Immunogen

Cardiac Troponin I peptide (KISASRKLQLKT).

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Surface Plasmon Resonance, Western Blot

Clone

scFv 180

Conjugate

Unconjugated

Gene

TNNI3

Gene Alias

alternatively spliced; cardiac ankyrin repeat kinase; Cardiac muscle troponin T; cardiac troponin I; cardiac troponin I isoform; cardiac troponin I-interacting kinase; cardiac troponin T; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, dilated 2A (autosomal recessive); cardiomyopathy, hypertrophic 2; CARK; CCDD; CMD1D; CMD1FF; CMD2A; CMH2; CMH7; CMPD2; cTnI; cTnT; Ctt; CTTG; D830019J24Rik; LVNC6; MGC116817; RATCTTG; RCM1; RCM3; Serine/threonine-protein kinase TNNI3K; Tn1; TnI; TNNC1; Tnni3; TNNI3 interacting kinase; TNNI3-interacting kinase; TNNI3K; tnni3k {ECO:0000250; TNNT2; Tnnt3; TnTc; Tpn1; troponin 1, type 3; troponin I type 3 (cardiac); troponin I, cardiac 3; troponin I, cardiac muscle; troponin I, cardiac muscle-like; troponin I3, cardiac type; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin T splicing mutant isoform 2; troponin T type 2 (cardiac); troponin T, cardiac muscle; troponin T2, cardiac; troponin T2, cardiac type; truncated cardiac troponin T; UniProtKB:Q59H18}

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7137

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG λ

Description

  • Specificity: This antibody binds specificially to the cardiac Troponin I Peptide KISASRKLQLKT
  • This epitope is 100% conserved among a great variety of mammalian species, including most monkeys, Squirrel, Hamster, Mouse, Rat, Rabbit, Whales, Mole-Rat, Antelope and several other mammals
  • Cardiac Troponin I (Cardiac-specific troponin I, TnI, Troponin I) is an integral inhibitory protein in cardiac muscle that exists as part of a complex with troponin C (TnC) and troponin T (TnT)
  • The TnT subunit of troponin binds to tropomyosin-t form, a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments
  • Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, anabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement
  • The measurements of blood TnI and TnT levels is an important diagnostics indicator of heart muscle damage, and can be used to differentiate between angina and myocardial infarction in patients with chest pains
  • Cardiac Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro
  • Mutations in the Cardiac Troponin I gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Compare Similar Items

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Img

Thermo Scientific

PIMA547956

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Antigen:
Cardiac Troponin I Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P19429
Gene Symbols:
TNNI3
Immunogen:
Cardiac Troponin I peptide (KISASRKLQLKT).
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Surface Plasmon Resonance, Western Blot
Clone:
scFv 180
Conjugate:
Unconjugated
Gene:
TNNI3
Gene Alias:
alternatively spliced; cardiac ankyrin repeat kinase; Cardiac muscle troponin T; cardiac troponin I; cardiac troponin I isoform; cardiac troponin I-interacting kinase; cardiac troponin T; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, dilated 2A (autosomal recessive); cardiomyopathy, hypertrophic 2; CARK; CCDD; CMD1D; CMD1FF; CMD2A; CMH2; CMH7; CMPD2; cTnI; cTnT; Ctt; CTTG; D830019J24Rik; LVNC6; MGC116817; RATCTTG; RCM1; RCM3; Serine/threonine-protein kinase TNNI3K; Tn1; TnI; TNNC1; Tnni3; TNNI3 interacting kinase; TNNI3-interacting kinase; TNNI3K; tnni3k {ECO:0000250; TNNT2; Tnnt3; TnTc; Tpn1; troponin 1, type 3; troponin I type 3 (cardiac); troponin I, cardiac 3; troponin I, cardiac muscle; troponin I, cardiac muscle-like; troponin I3, cardiac type; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin T splicing mutant isoform 2; troponin T type 2 (cardiac); troponin T, cardiac muscle; troponin T2, cardiac; troponin T2, cardiac type; truncated cardiac troponin T; UniProtKB:Q59H18}
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7137
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG λ

Img

Thermo Scientific

PIMA547958

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Antigen:
GCN4 Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P03069
Gene Symbols:
GCN4
Immunogen:
Biotinylated GCN4-peptide (HLENEVARLKK).
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Yeast
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Surface Plasmon Resonance, Western Blot
Clone:
C11L34
Conjugate:
Unconjugated
Gene:
GCN4
Gene Alias:
__
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
856709
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG λ

Img

Thermo Scientific

PIMA547959

--

Antigen:
SIRP beta/gamma
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
O00241, Q9P1W8
Gene Symbols:
SIRPB1, SIRPG
Immunogen:
Recombinant human SIRPgamma:CD4 fusion protein.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunoprecipitation
Clone:
OX117
Conjugate:
Unconjugated
Gene:
SIRPB1
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10326, 55423
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA547960

--

Antigen:
SIRP beta/gamma Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
O00241, Q9P1W8
Gene Symbols:
SIRPB1, SIRPG
Immunogen:
Recombinant human SIRPgamma:CD4 fusion protein.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunoprecipitation
Clone:
OX117
Conjugate:
Unconjugated
Gene:
SIRPB1
Gene Alias:
__
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10326, 55423
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ