PIMA548289

C5AR1 Recombinant Mouse Monoclonal Antibody (32-G1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA548289-Each-of-1 In Stock ₹ 44,961.78

PIMA548289 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

C5AR1

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P21730

Gene Symbols

C5AR1

Immunogen

This antibody was raised by immunizing mice a synthetic C5aR C-terminal phosphopeptide that contained phosphoserine instead of serine at position 334 and also at the neighboring phosphorylation sites Ser-332 and Ser-338.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Clone

32-G1

Conjugate

Unconjugated

Gene

C5AR1

Gene Alias

anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

728

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

Related Products

Img

Thermo Scientific

PIMA548294

--

Img

Thermo Scientific

PIMA548293

--

Img

Thermo Scientific

PIMA548191

--

Img

Thermo Scientific

PIMA548145

--

Img

Thermo Scientific

PIMA548291

--

Img

Thermo Scientific

PIMA548295

--

Img

Thermo Scientific

PIMA548296

--

Img

Thermo Scientific

PIMA548306

--

Description

  • Specificity: The 32-G1 antibody recognizes C5aR which has its serine 334 phosphorylated
  • The mAb 32-G1 reacted specifically with a C5aR peptide that contained phosphoserine 334 and also reacted with C5aRs that were isolated from C5a-stimulated, transfected RBL-C5aR cells
  • It did not recognize a receptor mutant (C5aR-S--) with alanine replacement of all six C-terminal serine phosphorylation sites
  • Antibody 32-G1 specifically reacts with C5aR phosphoserine 334, independent of the phosphorylation state of the neighboring serine residues
  • Studies with Bt2cAMP-treated U937 cells show that 32-G1 specifically reacts with ligand-activated C5aR at endogenous receptor expression levels but only weakly recognizes C5aR isolated from unstimulated cells
  • CD88, also known as C5aR1, is a C5a Anaphylatoxin Receptor that mediates the effects of one of the most potent chemotactic agents known
  • C5AR1 has been implicated in asthma, and its expression has been reported in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract
  • CD88 is the receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a
  • Functionally, CD88 stimulates chemotaxis, granule enzyme release and superoxide anion production
  • CD88 is also a component of the classical pathway of the complement cascade; it may be involved with tissue injury associated with ischemia or sepsis and it may be a component of the membrane attack complex
  • Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA548289

--


Antigen:
C5AR1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P21730

Gene Symbols:
C5AR1

Immunogen:
This antibody was raised by immunizing mice a synthetic C5aR C-terminal phosphopeptide that contained phosphoserine instead of serine at position 334 and also at the neighboring phosphorylation sites Ser-332 and Ser-338.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
32-G1

Conjugate:
Unconjugated

Gene:
C5AR1

Gene Alias:
anaphylatoxin C5a receptor; C5A; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a Receptor; C5AR; C5a-R; C5AR1; C5r1; Cd88; CD88 antigen; complement C5a receptor; complement C5a receptor 1; complement component 5 receptor 1; complement component 5, receptor 1; complement component 5a receptor 1; D7Msu1

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
728

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA548291

--


Antigen:
CCR5 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P51681

Gene Symbols:
CCR5

Immunogen:
This antibody was raised by immunizing mice with intact RBL-CCR5 cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
T21/8

Conjugate:
Unconjugated

Gene:
CCR5

Gene Alias:
AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1234

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA548293

--


Antigen:
Phospho-CCR5 (Ser349) Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P51681

Gene Symbols:
CCR5

Immunogen:
This antibody was raised by immunizing mice with a synthetic phosphopeptide (CEAPERA(pS)(pS)VYTR(pS)TGEQI(pS)VGL) corresponding to the C-terminal region of human CCR5.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
E11/19

Conjugate:
Unconjugated

Gene:
CCR5

Gene Alias:
AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1234

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA548294

--


Antigen:
Phospho-CCR5 (Ser337) Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P51681

Gene Symbols:
CCR5

Immunogen:
This antibody was raised by immunizing mice with a synthetic phospho peptide corresponding to the C-Terminal region of human CCR5 conjugated to BSA.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
V14/2

Conjugate:
Unconjugated

Gene:
CCR5

Gene Alias:
AM4-7; C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 (gene/pseudogene); C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; Ccr5; CCR-5; CD195; CD195 antigen; chemokine (C-C motif) receptor 5; chemokine (C-C) receptor 5; chemokine receptor CCR5; chemr13; CKR5; CKR-5; Cmkbr5; HIV-1 fusion coreceptor; IDDM22; MIP-1 alpha receptor

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1234

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ