PIMA548313

H4ac pan-acetyl (K8,K12,K16) Chimeric Recombinant Rabbit Monoclonal Antibody (KM-2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA548313-Each-of-1 In Stock ₹ 44,961.78

PIMA548313 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

H4ac pan-acetyl (K8,K12,K16) Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P62805

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8294, 8359, 8363, 8366, 8367, 8370

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

KM-2

Conjugate

Unconjugated

Gene

H4C1

Gene Symbols

H4C1, H4C11, H4C14, H4C2, H4C5, H4C9

Immunogen

KM-2 antibody was derived from an MRL/lpr lupus mouse.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • Specificity: KM-2 antibody recognizes the N-terminal peptides 1-20 of histone H2A and 1-29 of histone H4 which have a large sequence homology
  • Histone H4 acetylation on lysines 8, 12 and 16 significantly increases the antibody's binding while the acetylation at K5 decreases it
  • H4 acetylation at lysine residues 8, 12, and 16 is a well-characterized post-translational modification that is associated with transcriptional activation
  • This modification is catalyzed by histone acetyltransferases (HATs) and is often found at promoter regions of actively transcribed genes
  • It is believed to facilitate chromatin remodeling and transcription factor recruitment, μgtimately leading to increased gene expression
  • However, the precise mechanisms by which H4 acetylation at these specific lysine residues contributes to gene regulation are still under investigation.

Compare Similar Items

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Img

Thermo Scientific

PIMA548313

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Antigen:
H4ac pan-acetyl (K8,K12,K16) Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P62805

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8294, 8359, 8363, 8366, 8367, 8370

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
KM-2

Conjugate:
Unconjugated

Gene:
H4C1

Gene Symbols:
H4C1, H4C11, H4C14, H4C2, H4C5, H4C9

Immunogen:
KM-2 antibody was derived from an MRL/lpr lupus mouse.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

PIMA548314

--


Antigen:
H3K27me3 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P68431, Q71DI3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
126961, 333932, 8350, 8356, 8357, 8358, 8968

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Clone:
BT164

Conjugate:
Unconjugated

Gene:
H3C15

Gene Symbols:
H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7

Immunogen:
BT164 is a mice-derrived lupus antibody that was established by selection on apoptotic chromatin.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

PIMA548316

--


Antigen:
CD74 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P04233

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
972

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot

Clone:
LL1 (EPB1)

Conjugate:
Unconjugated

Gene:
CD74

Gene Symbols:
CD74

Immunogen:
This antibody was generated by immunizing female BALB/c mice with whole Raji cells or a crude membrane preparation.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

PIMA548317

--


Antigen:
CD40 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P25942

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
958

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Inhibition Assays

Clone:
chi220

Conjugate:
Unconjugated

Gene:
CD40

Gene Symbols:
CD40

Immunogen:
This antibody was generated by immunizing female BALB/c mice with a fusion protein containing extracellular domain of human CD40 fused to the hinge CH2 and CH3 domains of a murine IgG2b antibody.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid