PIMA548050

Mogamulizumab Chimeric Recombinant Rabbit Monoclonal Antibody (KW-0761 (Mogamulizumab)), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA548050-Each-of-1 In Stock ₹ 44,961.78

PIMA548050 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Mogamulizumab Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Target Species

Human

Form

Liquid

Applications

Functional Assay, Western Blot

Clone

KW-0761 (Mogamulizumab)

Conjugate

Unconjugated

Gene Alias

AMG-761; KW-0761

Immunogen

This antibody was prepared by humanization of a mouse anti-CCR4 mAb.

Quantity

200 μg

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

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Description

  • Specificity: This antibody is specific for human CCR4, a chemokine receptor that is preferentially expressed by Th2 and regulatory T (Treg) cells
  • CCR4 is also detected on basophils, platelets, monocytes and brain microvascular and coronary artery endothelial cells
  • Mogamulizumab is a humanized monoclonal antibody (mAb) directed against CC chemokine receptor 4 (CCR4) for the treatment of Mycosis Fungoides (MF) and Sezary Syndrome (SS), the most common subtypes of cutaneous T-cell lymphoma
  • Cutaneous T-cell lymphomas occur when certain white blood cells, called T cells, become cancerous; these cancers typically affect the skin, causing various types of skin lesions 8
  • On August 8 2018, the U
  • S
  • Food and pharmaceutical Administration (FDA) approved mogamulizumab injection (also known as Poteligeo) for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides (MF) or Sezary syndrome (SS) after at least one prior systemic therapy 7
  • Mogamulizumab is derived from Kyowa Hakko Kirin's POTELLIGENT (®) technology, which produces antibodies with enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) activity
  • Approval in Japan was granted on April 30 2012 by the Japanese Ministry of Health, Labor and Welfare for patients with relapsed or refractory CCR4-positive adult T-cell leukemia-lymphoma 2.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA548050

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Antigen:
Mogamulizumab Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Human

Form:
Liquid

Applications:
Functional Assay, Western Blot

Clone:
KW-0761 (Mogamulizumab)

Conjugate:
Unconjugated

Gene Alias:
AMG-761; KW-0761

Immunogen:
This antibody was prepared by humanization of a mouse anti-CCR4 mAb.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

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PIMA548051

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Antigen:
Epratuzumab

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Cynomolgus Monkey, Human, Rhesus Monkey

Form:
Liquid

Applications:
Flow Cytometry, Immunoprecipitation, Inhibition Assays

Clone:
hL22 (Epratuzumab)

Conjugate:
Unconjugated

Gene Alias:
90Y-DOTA-hLL2; 90Y-epratuzumab tetraxetan; 90Y-hLL2; AMG-412; hLL2

Immunogen:
This antibody was prepared by the humanization of LL2 (EPB-2), a murine anti-CD22 IgG2a raised against Raji Burkitt lymphoma cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

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Antigen:
Felvizumab

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Virus

Form:
Liquid

Applications:
ELISA, Functional Assay

Clone:
RSHZ19 (Felvizumab)

Conjugate:
Unconjugated

Gene Alias:
SB 209763

Immunogen:
This antibody was prepared by the humanization of an F protein-specific murine MAb, RSV19. More specifically, molecular techniques were used to insert the complementarity determining regions from murine RSV19 into a human IgG1 heavy and k light chain-variable domain framework.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

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Thermo Scientific

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Antigen:
Felvizumab Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Virus

Form:
Liquid

Applications:
ELISA, Functional Assay

Clone:
RSHZ19 (Felvizumab)

Conjugate:
Unconjugated

Gene Alias:
SB 209763

Immunogen:
This antibody was prepared by the humanization of an F protein-specific murine MAb, RSV19. More specifically, molecular techniques were used to insert the complementarity determining regions from murine RSV19 into a human IgG1 heavy and k light chain-variable domain framework.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ