PIMA548062

Tocilizumab Chimeric Recombinant Rabbit Monoclonal Antibody (rhPM-1 (Tocilizumab)), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA548062-Each-of-1 In Stock ₹ 44,961.78

PIMA548062 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Tocilizumab Chimeric

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Target Species

Human

Form

Liquid

Applications

ELISA, Immunocytochemistry, Inhibition Assays

Clone

rhPM-1 (Tocilizumab)

Conjugate

Unconjugated

Gene Alias

IL-6R; Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533

Immunogen

This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.

Quantity

200 μg

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG κ

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Description

  • Specificity: Tocilizumab binds specifically to both the membrane bound and soluble forms of human IL-6R
  • The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130
  • Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response
  • Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann-La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children
  • Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA548062

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Antigen:
Tocilizumab Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Inhibition Assays

Clone:
rhPM-1 (Tocilizumab)

Conjugate:
Unconjugated

Gene Alias:
IL-6R; Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533

Immunogen:
This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA548064

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Antigen:
DYKDDDDK Tag Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Tag

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
M2.1

Conjugate:
Unconjugated

Gene Alias:
DDDDK; DDDDK epitope tag; ECS epitope tag; ECS tag; FLAG; FLAG Tag

Immunogen:
Interleukin 2 genetically fused to the peptided DYKDDDDK, corresponding to the DDDDK epitope tag.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA548065

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Antigen:
CD40 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Inhibition Assays, T-Cell Activation

Clone:
A54 scFv

Conjugate:
Unconjugated

Gene Alias:
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5

Immunogen:
A54 human anti-CD40 scFv was selected from the n-CoDeR phage display library after 4 rounds of selections using biotinylated CD40-Fcgamma fusion protein as bait and subsequent capture of bound phages on streptavidin-caoted magnetic beads.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG λ

Img

Thermo Scientific

PIMA548066

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Antigen:
Bovine Serum Albumin

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Target Species:
Bovine

Form:
Liquid

Applications:
Immunoprecipitation

Clone:
D1

Conjugate:
Unconjugated

Gene Alias:
ALB; ALB protein; Alb1; Alb-1; albumin; albumin (32 AA); albumin (AA 34); albumin 1; Albza; ANALBA; Bos d 6; bovine albumin; bovine serum albumin; BSA; cell growth inhibiting protein 42; FDAH; GIG20; GIG42; growth-inhibiting protein 20; MGC179277; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619; PRO2675; Serum albumin; UNQ696/PRO1341

Immunogen:
D1 was prepared by isolating anti-p24 scFvs from a phage display library made from a mouse immunized with lysate from HIV-1 infected H9 cells.

Quantity:
200 μg

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ