PIMA548061
Tocilizumab Recombinant Human Monoclonal Antibody (rhPM-1 (Tocilizumab)), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA548061-Each-of-1 | In Stock | ₹ 44,961.78 |
PIMA548061 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,961.78
GST (18%): ₹ 8,093.12
Total Price: ₹ 53,054.90
Antigen
Tocilizumab
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Host Species
Human
Purification Method
Affinity chromatography
Regulatory Status
RUO
Target Species
Human
Form
Liquid
Applications
ELISA, Inhibition Assays
Clone
rhPM-1 (Tocilizumab)
Conjugate
Unconjugated
Gene Alias
IL-6R; Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533
Immunogen
This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
Quantity
200 μg
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1 κ
Related Products
Description
- Specificity: Tocilizumab binds specifically to both the membrane bound and soluble forms of human IL-6R
- The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130
- Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response
- Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann-La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children
- Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects.
Compare Similar Items
Show Difference
Antigen: Tocilizumab
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Applications: ELISA, Inhibition Assays
Clone: rhPM-1 (Tocilizumab)
Conjugate: Unconjugated
Gene Alias: IL-6R; Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533
Immunogen: This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
Tocilizumab
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Inhibition Assays
Clone:
rhPM-1 (Tocilizumab)
Conjugate:
Unconjugated
Gene Alias:
IL-6R; Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533
Immunogen:
This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ
Antigen: Tocilizumab Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Inhibition Assays
Clone: rhPM-1 (Tocilizumab)
Conjugate: Unconjugated
Gene Alias: IL-6R; Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533
Immunogen: This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
Tocilizumab Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Inhibition Assays
Clone:
rhPM-1 (Tocilizumab)
Conjugate:
Unconjugated
Gene Alias:
IL-6R; Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533
Immunogen:
This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: DYKDDDDK Tag Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Tag
Form: Liquid
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: M2.1
Conjugate: Unconjugated
Gene Alias: DDDDK; DDDDK epitope tag; ECS epitope tag; ECS tag; FLAG; FLAG Tag
Immunogen: Interleukin 2 genetically fused to the peptided DYKDDDDK, corresponding to the DDDDK epitope tag.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
DYKDDDDK Tag Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Tag
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
M2.1
Conjugate:
Unconjugated
Gene Alias:
DDDDK; DDDDK epitope tag; ECS epitope tag; ECS tag; FLAG; FLAG Tag
Immunogen:
Interleukin 2 genetically fused to the peptided DYKDDDDK, corresponding to the DDDDK epitope tag.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: CD40 Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Inhibition Assays, T-Cell Activation
Clone: A54 scFv
Conjugate: Unconjugated
Gene Alias: AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5
Immunogen: A54 human anti-CD40 scFv was selected from the n-CoDeR phage display library after 4 rounds of selections using biotinylated CD40-Fcgamma fusion protein as bait and subsequent capture of bound phages on streptavidin-caoted magnetic beads.
Quantity: 200 μg
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG λ
Antigen:
CD40 Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Inhibition Assays, T-Cell Activation
Clone:
A54 scFv
Conjugate:
Unconjugated
Gene Alias:
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5
Immunogen:
A54 human anti-CD40 scFv was selected from the n-CoDeR phage display library after 4 rounds of selections using biotinylated CD40-Fcgamma fusion protein as bait and subsequent capture of bound phages on streptavidin-caoted magnetic beads.
Quantity:
200 μg
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG λ