PIMA548347
CD33 Chimeric Recombinant Rabbit Monoclonal Antibody (M195), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA548347-Each-of-1 | In Stock | ₹ 44,961.78 |
PIMA548347 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,961.78
GST (18%): ₹ 8,093.12
Total Price: ₹ 53,054.90
Antigen
CD33 Chimeric
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Gene Accession No.
P20138
Gene Symbols
CD33
Immunogen
The original antibody was generated by immunizing mice with live leukemic myeloblasts.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Functional Assay, Immunocytochemistry, Radioimmune Assays (RIA)
Clone
M195
Conjugate
Unconjugated
Gene
CD33
Gene Alias
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
945
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG κ
Related Products
Description
- Specificity: This antibody binds CD33, which is a 67 kD glycoprotein expressed on monocytes, hematopoetic progenitors, early myeloid progenitor cells and myeloid leukemias (acute and chronic) but not expressed on mature myeloid cells, normal stem cells, other hemtopoietic cells and non hematopoietic human tissues
- CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family
- It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, and these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface
- CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia
- Further, CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells
- CD33 is also expressed on, and is a useful marker for, peripheral monocytes
- CD33 is useful for distinguishing myelogenous leukemia cells from lymphoid or erythroid leukemias
- Diseases associated with CD43 dysfunction include gallbladder lymphoma and extracutaneous mastocytoma.
Compare Similar Items
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Antigen: CD33 Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P20138
Gene Symbols: CD33
Immunogen: The original antibody was generated by immunizing mice with live leukemic myeloblasts.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Immunocytochemistry, Radioimmune Assays (RIA)
Clone: M195
Conjugate: Unconjugated
Gene: CD33
Gene Alias: CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 945
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
CD33 Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P20138
Gene Symbols:
CD33
Immunogen:
The original antibody was generated by immunizing mice with live leukemic myeloblasts.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Radioimmune Assays (RIA)
Clone:
M195
Conjugate:
Unconjugated
Gene:
CD33
Gene Alias:
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
945
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: CD18 Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P05107
Gene Symbols: ITGB2
Immunogen: The original antibody was generated by immunizing BALB/c mice with alloantigen activated T cells.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Inhibition Assays, Western Blot
Clone: 60.3
Conjugate: Unconjugated
Gene: ITGB2
Gene Alias: 2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3689
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
CD18 Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P05107
Gene Symbols:
ITGB2
Immunogen:
The original antibody was generated by immunizing BALB/c mice with alloantigen activated T cells.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Inhibition Assays, Western Blot
Clone:
60.3
Conjugate:
Unconjugated
Gene:
ITGB2
Gene Alias:
2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3689
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: Mesothelin Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: Q13421
Gene Symbols: MSLN
Immunogen: The original antibody was generated by intraperitoneally immunizing BALB/c mice with the purified recombinant mesothelin protein.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone: 11-25
Conjugate: Unconjugated
Gene: MSLN
Gene Alias: CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10232
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
Mesothelin Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
Q13421
Gene Symbols:
MSLN
Immunogen:
The original antibody was generated by intraperitoneally immunizing BALB/c mice with the purified recombinant mesothelin protein.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunoprecipitation
Clone:
11-25
Conjugate:
Unconjugated
Gene:
MSLN
Gene Alias:
CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10232
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: Mesothelin
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: Q13421
Gene Symbols: MSLN
Immunogen: The original antibody was generated by intraperitoneally immunizing BALB/c mice with the purified recombinant mesothelin protein.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA
Clone: IC14-30
Conjugate: Unconjugated
Gene: MSLN
Gene Alias: CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10232
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
Mesothelin
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
Q13421
Gene Symbols:
MSLN
Immunogen:
The original antibody was generated by intraperitoneally immunizing BALB/c mice with the purified recombinant mesothelin protein.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA
Clone:
IC14-30
Conjugate:
Unconjugated
Gene:
MSLN
Gene Alias:
CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10232
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ