PIMA549299

NDFIP2 Monoclonal Antibody (10D6D7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA549299-Each-of-1 In Stock ₹ 34,908.48

PIMA549299 - Each of 1

₹ 34,908.48

In Stock

Quantity

1

Base Price: ₹ 34,908.48

GST (18%): ₹ 6,283.526

Total Price: ₹ 41,192.006

Antigen

NDFIP2

Classification

Monoclonal

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and no preservative

Gene Accession No.

Q9NV92

Gene Symbols

NDFIP2

Immunogen

E.coli-derived human NDFIP2 recombinant protein (Position: M16-L336).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

10D6D7

Conjugate

Unconjugated

Gene

NDFIP2

Gene Alias

0710001O20Rik; 2810436B12Rik; 9130207N19Rik; KIAA1165; MAPK-activating protein PM04 PM05 PM06 PM07; mKIAA1165; N4wbp5a; NDFIP2; Nedd4 family interacting protein 2; NEDD4 family-interacting protein 2; NEDD4 WW domain-binding protein 5A; NF-kappa-B-activating protein 413; putative MAPK-activating protein PM04/PM05/PM06/PM07; Putative NF-kappa-B-activating protein 413; Unknown (protein for IMAGE:7958216); wu:fa92h03; wu:fk31f07; zgc:63948

Host Species

Mouse

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54602

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b

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Description

  • Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
  • Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets
  • As a result, may control many cellular processes
  • Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes
  • Negatively regulates KCNH2 potassium channel activity by decreasing its cell-surface expression and interfering with channel maturation through recruitment of NEDD4L to the Golgi apparatus and multivesicular body where it mediates KCNH2 degradation (PubMed:26363003)
  • May modulate EGFR signaling
  • Together with NDFIP1, limits the cytokine signaling and expansion of effector Th2 T-cells by promoting degradation of JAK1, probably by ITCH- and NEDD4L-mediated ubiquitination
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA549299

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Antigen:
NDFIP2

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
Q9NV92

Gene Symbols:
NDFIP2

Immunogen:
E.coli-derived human NDFIP2 recombinant protein (Position: M16-L336).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
10D6D7

Conjugate:
Unconjugated

Gene:
NDFIP2

Gene Alias:
0710001O20Rik; 2810436B12Rik; 9130207N19Rik; KIAA1165; MAPK-activating protein PM04 PM05 PM06 PM07; mKIAA1165; N4wbp5a; NDFIP2; Nedd4 family interacting protein 2; NEDD4 family-interacting protein 2; NEDD4 WW domain-binding protein 5A; NF-kappa-B-activating protein 413; putative MAPK-activating protein PM04/PM05/PM06/PM07; Putative NF-kappa-B-activating protein 413; Unknown (protein for IMAGE:7958216); wu:fa92h03; wu:fk31f07; zgc:63948

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54602

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

PIMA549302

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Antigen:
LSM8

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
O95777, Q6ZWM4

Gene Symbols:
LSM8

Immunogen:
E.coli-derived human LSM8 recombinant protein (Position: M1-H96).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
6B11

Conjugate:
Unconjugated

Gene:
LSM8

Gene Alias:
2010003I05Rik; AW214405; Lsm8; LSM8 homolog, U6 small nuclear RNA associated; LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae); LSM8 U6 small nuclear RNA associated; MAK31-like protein; Naa38; N-alpha-acetyltransferase 38, NatC auxiliary subunit; N-alpha-acetyltransferase 38, NatC auxiliary subunit; LSM8 homolog, U6 small nuclear RNA associated; U6 snRNA-associated Sm-like protein LSm8

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
296913, 51691, 76522

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2a

Img

Thermo Scientific

PIMA549303

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Antigen:
PMPCB

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
O75439, Q03346, Q9CXT8

Gene Symbols:
PMPCB

Immunogen:
E.coli-derived human MPPB/PMPCB recombinant protein (Position: E23-Q479).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
9F13E4

Conjugate:
Unconjugated

Gene:
PMPCB

Gene Alias:
3110004O18Rik; Beta-MPP; mitochondrial processing peptidase beta subunit; mitochondrial-processing peptidase subunit beta; MPP11; MPPB; MPPP52; P-52; peptidase (mitochondrial processing) beta; peptidase, mitochondrial processing beta subunit; PMPCB

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64198, 73078, 9512

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG2b

Img

Thermo Scientific

PIMA549304

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Antigen:
GNG4

Classification:
Monoclonal

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
P50153

Gene Symbols:
GNG4

Immunogen:
E.coli-derived human GNG4 recombinant protein (Position: M1-D52).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Form:
Lyophilized

Applications:
Western Blot

Clone:
7B6

Conjugate:
Unconjugated

Gene:
GNG4

Gene Alias:
G protein subunit gamma 4; Gng4; GNGT4; guanine nucleotide binding protein (G protein), gamma 4; guanine nucleotide binding protein (G protein), gamma 4 subunit; guanine nucleotide binding protein 4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114118, 14706

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1