PIPA5100882

NDFIP2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5100882-Each-of-1 In Stock ₹ 44,705.10

PIPA5100882 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NDFIP2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NDFIP2

Gene Alias

0710001O20Rik; 2810436B12Rik; 9130207N19Rik; KIAA1165; MAPK-activating protein PM04 PM05 PM06 PM07; mKIAA1165; N4wbp5a; NDFIP2; Nedd4 family interacting protein 2; NEDD4 family-interacting protein 2; NEDD4 WW domain-binding protein 5A; NF-kappa-B-activating protein 413; putative MAPK-activating protein PM04/PM05/PM06/PM07; Putative NF-kappa-B-activating protein 413; Unknown (protein for IMAGE:7958216); wu:fa92h03; wu:fk31f07; zgc:63948

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54602, 76273

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q91ZP6, Q9NV92

Gene Symbols

NDFIP2

Immunogen

A synthesized peptide derived from human NDFIP2(Accession Q9NV92), corresponding to amino acid residues G61-E111.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total NDFIP2
  • Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets
  • As a result, may control many cellular processes
  • Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes
  • Negatively regulates KCNH2 potassium channel activity by decreasing its cell-surface expression and interfering with channel maturation through recruitment of NEDD4L to the Golgi apparatus and multivesicular body where it mediates KCNH2 degradation (PubMed:26363003)
  • May modulate EGFR signaling
  • Together with NDFIP1, limits the cytokine signaling and expansion of effector Th2 T-cells by promoting degradation of JAK1, probably by ITCH- and NEDD4L-mediated ubiquitination
  • [UniProt]

Compare Similar Items

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Img

Thermo Scientific

PIPA5100882

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Antigen:
NDFIP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NDFIP2

Gene Alias:
0710001O20Rik; 2810436B12Rik; 9130207N19Rik; KIAA1165; MAPK-activating protein PM04 PM05 PM06 PM07; mKIAA1165; N4wbp5a; NDFIP2; Nedd4 family interacting protein 2; NEDD4 family-interacting protein 2; NEDD4 WW domain-binding protein 5A; NF-kappa-B-activating protein 413; putative MAPK-activating protein PM04/PM05/PM06/PM07; Putative NF-kappa-B-activating protein 413; Unknown (protein for IMAGE:7958216); wu:fa92h03; wu:fk31f07; zgc:63948

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54602, 76273

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q91ZP6, Q9NV92

Gene Symbols:
NDFIP2

Immunogen:
A synthesized peptide derived from human NDFIP2(Accession Q9NV92), corresponding to amino acid residues G61-E111.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100883

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Antigen:
SLC35B2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC35B2

Gene Alias:
1110003M08Rik; 3'-phosphoadenosine 5'-phosphosulfate transporter; AA407792; Adenosine 3'-phospho 5'-phosphosulfate transporter 1; AI842275; J207; PAPS transporter 1; PAPST1; PSEC0149; Putative MAPK-activating protein PM15; putative NF-kappa-B-activating protein 48; Slc35b1; SLC35B2; SLL; solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2; solute carrier family 35 member B2; solute carrier family 35 member B2 variant 2; solute carrier family 35, member B1; solute carrier family 35, member B2; UGTrel4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
347734, 501103, 73836

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8TB61, Q91ZN5

Gene Symbols:
SLC35B2

Immunogen:
A synthesized peptide derived from human SLC35B2(Accession Q8TB61), corresponding to amino acid residues H388-V432.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100884

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Antigen:
SMARCAD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMARCAD1

Gene Alias:
ADERM; ATP-dependent helicase 1; ATP-dependent helicase SMARCAD1; AV081750; AW226546; D6Pas1; DKFZP762K2015; enhancer trap locus 1; enhancer trap locus homolog 1; Etl1; Etl-1; HEL1; hHEL1; KIAA1122; mKIAA1122; Smarcad1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1; SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56916

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9H4L7

Gene Symbols:
SMARCAD1

Immunogen:
A synthesized peptide derived from human SMARCAD1(Accession Q9H4L7), corresponding to amino acid residues S313-G363.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100885

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Antigen:
SP5/SP8/SP9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SP9

Gene Alias:
BTD; buttonhead-like zinc finger transcription factor Sp9; D930049B17Rik; mBtd; SP5; Sp5 transcription factor; SP8; Sp8 transcription factor; Sp9; Sp9 transcription factor; Sp9 transcription factor homolog; specificity protein 8; trans-acting transcription factor 5; trans-acting transcription factor 8; trans-acting transcription factor 9; transcription factor Sp5; Transcription factor Sp8; transcription factor Sp9; zinc finger protein 990; ZNF990

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100131390, 221833, 320145, 381373, 389058, 64406

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P0CG40, Q64HY3, Q6BEB4, Q8BMJ8, Q8IXZ3, Q9JHX2

Gene Symbols:
Sp5, Sp8, SP9

Immunogen:
A synthesized peptide derived from human SP5(Accession Q6BEB4), corresponding to amino acid residues T260-T310.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG