PIPA1087

Phospho-Huntingtin (Ser421) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA1087-Each-of-1 In Stock ₹ 49,624.80

PIPA1087 - Each of 1

₹ 49,624.80

In Stock

Quantity

1

Base Price: ₹ 49,624.80

GST (18%): ₹ 8,932.464

Total Price: ₹ 58,557.264

Antigen

Phospho-Huntingtin (Ser421)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Htt

Gene Alias

AI256365; C430023I11Rik; Hd; HD protein; HD protein homolog; Hdh; HTT; Huntingtin; huntingtin (Huntington disease); Huntingtin, myristoylated N-terminal fragment; Huntington disease gene homolog; huntington disease protein; huntington disease protein homolog; IT15; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15194, 3064

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

0.24 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P42858, P42859

Gene Symbols

Htt

Immunogen

Synthetic phosphopeptide conjugated to KLH corresponding to residues GGRSRSG(pS)IVELI (414-426) of Human HTT

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Description PA1-087 has been successfully used in immunofluorescence, immunohistochemistry, and Western blotting applications on human and mouse samples
  • Huntingtin is a disease gene linked to Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons
  • This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product
  • HD is a mid-life onset autosomal dominant neurodegenerative disease that is characterized by psychiatric disorders, dementia, and involuntary movements (chorea), leading to death in 10-20 years.The huntingtin locus is large, spanning 180 kb and consisting of 67 exons
  • The huntingtin gene is widely expressed and is required for normal development
  • It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues
  • The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10.3 kb is more widely expressed
  • The genetic defect leading to Huntington's disease may not necessarily eliminate transcription, but may confer a new property on the mRNA or alter the function of the protein.

Compare Similar Items

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Thermo Scientific

PIPA1087

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Antigen:
Phospho-Huntingtin (Ser421)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Htt

Gene Alias:
AI256365; C430023I11Rik; Hd; HD protein; HD protein homolog; Hdh; HTT; Huntingtin; huntingtin (Huntington disease); Huntingtin, myristoylated N-terminal fragment; Huntington disease gene homolog; huntington disease protein; huntington disease protein homolog; IT15; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15194, 3064

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
0.24 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P42858, P42859

Gene Symbols:
Htt

Immunogen:
Synthetic phosphopeptide conjugated to KLH corresponding to residues GGRSRSG(pS)IVELI (414-426) of Human HTT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA1091

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Antigen:
RAC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rac1

Gene Alias:
AL023026; cell migration-inducing gene 5 protein; D5Ertd559e; GTPase; MGC111543; MIG5; p21-Rac1; Rac 1b; Rac family small GTPase 1; RAC1; Rac-1; Rac2; rac2 GTP-binding protein; ras-like protein TC25; RAS-related C3 botulinum substrate 1; ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1); ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); rho family, small GTP binding protein Rac1; TC25; TC-25

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19353, 5879

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P63000, P63001

Gene Symbols:
Rac1

Immunogen:
Recombinant Full-length Human Protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA1092

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Antigen:
Cdc42

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC42

Gene Alias:
AI747189; AU018915; CDC42; CDC42Hs; Cell division control protein 42 homolog; cell division cycle 42; cell division cycle 42 (GTP binding protein); cell division cycle 42 homolog; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K; G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; GTP-binding protein; RP1-224A6.5; small GTP binding protein CDC42; TKS

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12540, 64465, 998

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P60766, P60953, Q8CFN2

Gene Symbols:
CDC42

Immunogen:
C-Terminal truncated human recombinant protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA1092X

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Antigen:
Cdc42

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC42

Gene Alias:
AI747189; AU018915; CDC42; CDC42Hs; Cell division control protein 42 homolog; cell division cycle 42; cell division cycle 42 (GTP binding protein); cell division cycle 42 homolog; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K; G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; GTP-binding protein; RP1-224A6.5; small GTP binding protein CDC42; TKS

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12540, 64465, 998

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P60766, P60953, Q8CFN2

Gene Symbols:
CDC42

Immunogen:
C-Terminal truncated human recombinant protein

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG