PIPA125098

Connexin 43 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA125098-Each-of-1 In Stock ₹ 47,015.22

PIPA125098 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

Connexin 43

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GJA1

Gene Alias

alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100689077, 14609, 24392, 2697

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration

0.7 mg/mL

Formulation

0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

P08050, P17302, P23242

Gene Symbols

GJA1

Immunogen

Synthetic peptide, conjugated to KLH, corresponding to residues K(362) P S S R A S S R A S S R P R P D D L E I(382) of human GJA1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Hamster, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: BHK
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Connexin 43 (Cx43) is a member of the gap junction protein family
  • Connexins assemble as a hexamer and are transported to the plasma membrane to create a hemichannel that can associate with hemichannels on nearby cells to create cell-to-cell channels
  • Clusters of these channels assemble to make gap junctions
  • Gap junction communication is important in development and regulation of cell growth
  • Phosphorylation of Cx43 is important in regulating assembly and function of gap junctions
  • Ser368 of Cx43 is phosphorylated by protein kinase C (PKC) after activation by phorbol esters, which decreases cell-to-cell communication
  • Src can interact with and phosphorylate Cx43 to alter gap junction communication
  • GFAP are membrane-spanning proteins that facilitate the transfer of ions and small molecules between cells
  • According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta
  • Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development
  • Connexin 43 is also targeted by several protein kinases that regulate myocardial cell-cell coupling
  • A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5
  • Mutations in the GFAP gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy, oculodentodigital dysplasia and heart malformations
  • Alternatively spliced transcript variants of GFAP have been found.

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Show Difference

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Thermo Scientific

PIPA125098

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Antigen:
Connexin 43

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GJA1

Gene Alias:
alpha 1 connexin; AU042049; AVSD3; AW546267; CMDR; Cnx43; connexin 43; connexin43; connexin-43; cx43; Cx-43; cx43 protein; cx43a1; Cx43alpha1; CXA1; Cxn-43; DFNB38; EKVP; etID309742.9; gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction membrane channel protein; gap junction membrane channel protein alpha 1; gap junction protein; gap junction protein alpha 1; gap junction protein connexin 43; gap junction protein, alpha 1; gap junction protein, alpha 1, 43 kD (connexin 43); gap junction protein, alpha 1, 43kDa; gap junction protein, alpha 1, 43kDa (connexin 43); gja1; Gja-1; GJAL; HLHS1; HSS; Npm1; ODD; ODDD; ODOD; PPKCA; SDTY3; shf; Short fin protein; sof; stopsel; stp; Syndactyly type III; vascular smooth muscle connexin43; Vascular smooth muscle connexin-43; zfCx43.3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100689077, 14609, 24392, 2697

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.7 mg/mL

Formulation:
0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P08050, P17302, P23242

Gene Symbols:
GJA1

Immunogen:
Synthetic peptide, conjugated to KLH, corresponding to residues K(362) P S S R A S S R A S S R P R P D D L E I(382) of human GJA1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA125136

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Antigen:
MAGI1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Magi1

Gene Alias:
AIP3; AIP-3; Atrophin-1-interacting protein 3; BAI1-associated protein 1; Baiap1; BAP1; BAP-1; Gukmi1; MAGI1; Magi-1; MAGI1c; Magi1d; membrane associated guanylate kinase, WW and PDZ domain containing 1; membrane-associated guanylate kinase inverted 1; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; mKIAA4129; TNRC19; Trinucleotide repeat-containing gene 19 protein; WW domain-containing protein 3; WWP3

Host Species:
Rabbit

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
14924, 500261, 9223

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
antibody with no preservative

Gene Accession No.:
Q4L1J4, Q6RHR9, Q96QZ7

Gene Symbols:
Magi1

Immunogen:
Synthetic peptide, conjugated to KLH, corresponding to residues 282-296 of MAGI1.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA125150

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Antigen:
NPHP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPHP1

Gene Alias:
JBTS4; juvenile nephronophthisis 1 protein; nephrocystin 1; Nephrocystin1; nephrocystin-1; nephronophthisis 1 (juvenile); nephronophthisis 1 (juvenile) homolog; nephronophthisis 1 (juvenile) homolog (human); NPH1; NPHP1; SLSN1

Host Species:
Rabbit

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
53885

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9QY53

Gene Symbols:
NPHP1

Immunogen:
Fusion protein corresponding to the pic region (residues 612-691) of mouse NPH.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA125152

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Antigen:
Osteopontin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPP1

Gene Alias:
2AR; 2b7; 44 kDa bone phosphoprotein; Apl-1; BNSP; Bone sialoprotein 1; Bone sialoprotein 1 (BSPI/BSP1); Bsp; BSPI; Calcium oxalate crystal growth inhibitor protein; CALPHA1 fusion; Early T lymphocyte activation 1 (ETA1); early T-lymphocyte activation 1; early T-lymphocyte activation 1 protein; Eta; ETA-1; HGNC:11255; immunoglobulin alpha 1 heavy chain constant region fusion protein; MGC110940; Minopontin; nephropontin; Op; Opn; Opnl; OSP; osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; osteopontin-like protein; PSEC0156; Ric; Secreted phosphoprotein 1; secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1); secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); Secreted phosphoprotein 1 (SPP1); secreted phosphoprotein 1 variant 6; Sialoprotein (osteopontin); SPP1; SPP-1; SPP1/CALPHA1 fusion; unnamed protein product; urinar; urinary stone protein; Uropontin

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20750

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry, Inhibition Assays, Neutralization, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with 5% trehalose and no preservative

Gene Accession No.:
P10923

Gene Symbols:
SPP1

Immunogen:
Recombinant, full length mouse protein, expressed in NSO cells.

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG