PIPA127958

MDMX Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA127958-Each-of-1 In Stock ₹ 52,704.96

PIPA127958 - Each of 1

₹ 52,704.96

In Stock

Quantity

1

Base Price: ₹ 52,704.96

GST (18%): ₹ 9,486.893

Total Price: ₹ 62,191.853

Antigen

MDMX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MDM4

Gene Alias

4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4194

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.

O15151

Gene Symbols

MDM4

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human MDM4

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: HepG2, MCF-7
  • Predicted reactivity: Cow: 80%; Dog: 93%; Horse: 93%; Pig: 86%; Rabbit: 80%
  • Use at a concentration of 1 μg/mL in 5% skim milk/PBS buffer
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The MDM2 protein is the primary regulator of p53 protein stability
  • MDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations with MDM2
  • The gene that encodes MDMX (also designated MDM4) is a target for amplification in malignant gliomas
  • ARF interacts with MDMX to sequester MDMX within the nucleolus
  • This sequestration of MDMX by ARF results in an increase in p53 transactivation
  • In addition, expression of MDMX can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation
  • Like MDM2, MDMX also binds p73 and stabilizes the level of p73
  • Therefore, in striking contrast to p53, the half-life of p73 is increased by binding to MDM2.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA127958

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Antigen:
MDMX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MDM4

Gene Alias:
4933417N07Rik; AA414968; AL023055; AU018793; AU021806; C85810; DKFZp781B1423; double minute 4 homolog; double minute 4 protein; double minute 4, human homolog of; p53-binding protein; HDMX; human homolog of; Mdm2-like p53-binding protein; MDM4; Mdm4 p53 binding protein homolog; MDM4 protein variant G; MDM4 protein variant Y; MDM4, p53 regulator; MDM4-related protein 1; Mdmx; MGC132766; MRP1; p53-binding protein Mdm4; Protein Mdm4; protein Mdmx; RP11-430C7.1; transformed mouse 3T3 cell double minute 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4194

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 2% sucrose and 0.09% sodium azide

Gene Accession No.:
O15151

Gene Symbols:
MDM4

Immunogen:
A synthetic peptide corresponding to a N-terminal region of Human MDM4

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA127973

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Antigen:
Prodynorphin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdyn

Gene Alias:
ADCA; Alpha-neoendorphin; beta-neoendorphin; Beta-neoendorphin-dynorphin; Big Dyn; Big dynorphin; Dyn; Dyn-A17; Dyn-B; Dynorphin A(1-13); dynorphin A(1-17); Dynorphin A(1-8); Dynorphin B; Dynorphin B(1-13); Dynorphin B-29; Leu-enkephalin; leumorphin; neoendorphin-dynorphin-enkephalin prepropeptide; PDYN; PENKB; Preprodynorphin; preproenkephalin B; prodynorphin; proenkephalin B; proenkephalin-B; Rimorphin; SCA23; unnamed protein product

Host Species:
Guinea Pig

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100135596, 445529

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Frozen)

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
P01214, Q60478

Gene Symbols:
Pdyn

Immunogen:
synthetic peptide QEDPNAYSEEFFDV, corresponding to amino acids 232-245 of Guinea pig ProDynorphin.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Guinea Pig, Porcine

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA127980

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Antigen:
NPY

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPY

Gene Alias:
0710005A05Rik; C-flanking peptide of NPY; CPON; involved in appetite regulation; LOC100912228; Neuropeptide tyrosine; Neuropeptide Y; neuropeptide Y precursor; Neuropeptide-Y; Npy; NPY02; OTTHUMP00000201947; prepro-neuropeptide Y; proneuropeptide Y; pro-neuropeptide Y; pro-neuropeptide Y-like; PYY4; RATNPY; RATNPY02

Host Species:
Guinea Pig

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100912228, 109648, 24604

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Frozen)

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P07808, P57774

Gene Symbols:
NPY

Immunogen:
synthetic peptide SDLLMRESTENAPRTR, corresponding to amino acids 76-91 of Rat Neuropeptide Y.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA127986

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Antigen:
MDC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCL22

Gene Alias:
A-152E5.1; Abcd1; ABCD-1; Activated B and dendritic cell-derived; AW060611; CC chemokine ABCD-1; CC chemokine STCP-1; C-C motif chemokine 22; C-C motif chemokine ligand 22; Ccl22; chemokine (C-C motif) ligand 22; DC/B-CK; DCBCK; dendritic cell and B cell derived chemokine; macrophage-derived chemokine; MDC; MDC(1-69); MDC(3-69); MDC(5-69); MDC(7-69); MGC108943; MGC34554; RP24-69A20.1; Scya22; small inducible cytokine A22; SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED); small inducible cytokine subfamily A (Cys-Cys) member 22; small inducible cytokine subfamily A (Cys-Cys), member 22; small inducible cytokine subfamily A, member 22; small inducible cytokine subfamily A22; small-inducible cytokine A22; STCP-1; stimulated T cell chemotactic protein 1; stimulated T-cell chemotactic protein 1

Host Species:
Chicken

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6367

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O00626

Gene Symbols:
CCL22

Immunogen:
Purified recombinant human MDC, expressed in E. coli.

Quantity:
25 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgY