PIPA186828

Aurora B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA186828-Each-of-1 In Stock ₹ 47,015.22

PIPA186828 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

Aurora B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AURKB

Gene Alias

Aik2; AIM1; AIM-1; AIRK2; AL022959; ARK2; ARK-2; AurB; AURKB; aurkb-sv1; aurkb-sv2; aurora 1; aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-B; STK1; STK-1; Stk12; STK12; AIK2; AIM1; ARK2; IPL1; AIM-1; STK5

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

114592, 20877, 360192, 396955, 479492, 9212

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Western Blot

Concentration

0.2 mg/mL

Formulation

PBS with <0.1% sodium azide; pH 7.2

Gene Accession No.

O55099, O70126, Q7YRC6, Q96GD4, Q9N0X0

Gene Symbols

AURKB

Immunogen

Synthetic peptide corresponding to amino acids 227-238 of human Aurora-B kinase

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Bovine, Canine, Human, Mouse, Non-human Primate, Porcine, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Predicted to react with bovine, chimpanzee, dog, mouse, pig and rat based on sequence homology
  • In Western blot, this antibody detects a band at ∽39kDa in HeLa cell lysate
  • Rabbit anti Human Aurora-B kinase antibody detects human Aurora-B kinase (AurB), a serine/threonine kinase which is the enzymatic core of the Chromosomal Passenger Complex (CPC)
  • The Aurora kinases associate with microtubules during chromosome movement and segregation
  • AURKB (Aurora B) localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers
  • This complex functions in chromosome alignment and separation, histone modification, and cytokinesis
  • CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localization, stability, and possibly even the substrate specificity of AurB
  • Two CPCs exist during mitosis: one containing all four members and another consisting of INCENP and AurB
  • Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3
  • AurB is overexpressed in a number of tumours, including primary breast and colon tumour samples
  • Its expression in tumours seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.

Compare Similar Items

Show Difference

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PIPA186828

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Antigen:
Aurora B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AURKB

Gene Alias:
Aik2; AIM1; AIM-1; AIRK2; AL022959; ARK2; ARK-2; AurB; AURKB; aurkb-sv1; aurkb-sv2; aurora 1; aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-B; STK1; STK-1; Stk12; STK12; AIK2; AIM1; ARK2; IPL1; AIM-1; STK5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114592, 20877, 360192, 396955, 479492, 9212

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with <0.1% sodium azide; pH 7.2

Gene Accession No.:
O55099, O70126, Q7YRC6, Q96GD4, Q9N0X0

Gene Symbols:
AURKB

Immunogen:
Synthetic peptide corresponding to amino acids 227-238 of human Aurora-B kinase

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Human, Mouse, Non-human Primate, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA186910

--


Antigen:
IL-19

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IL19

Gene Alias:
il 19; IL-10C; IL19; IL-19; ILN; Interleukin; interleukin 19; Interleukin19; interleukin-19; MDA1; MDA-1; melanoma differentiation associated protein-like protein; melanoma differentiation-associated protein-like protein; NG.1; ZMDA1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29949

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ELISA, Western Blot

Concentration:
0.1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
Q9UHD0

Gene Symbols:
IL19

Immunogen:
Recombinant human IL-19

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA186925

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Antigen:
IL-25

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IL25

Gene Alias:
D17Wsu104e; il 17e; Il17e; IL-17E; Il25; IL-25; ILN; Interleukin; interleukin 17E; interleukin 25; interleukin-17E; Interleukin-25; Ly6elg; Mydgf; myeloid derived growth factor; myeloid-derived growth factor; RGD1561632; UNQ3120/PRO10272; UPF0556 protein C19orf10 homolog

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140806

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
ELISA, Western Blot

Concentration:
__

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
0

Gene Symbols:
IL25

Immunogen:
Recombinant mouse SF-20

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA186940

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Antigen:
CHRM3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CHRM3

Gene Alias:
acetylcholine receptor; acetylcholine receptor, muscarinic 3; AChR M3; cholinergic receptor; cholinergic receptor muscarinic 3; cholinergic receptor, muscarinic 3; cholinergic receptor, muscarinic 3, cardiac; CHRM3; Chrm-3; EGBRS; HM3; M3; m3 muscarinic receptor; M3R; Mm3 mAChR; muscarinic acetylcholine receptor 3; muscarinic acetylcholine receptor M3; PBS

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1131

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
PBS with <0.1% sodium azide

Gene Accession No.:
P20309

Gene Symbols:
CHRM3

Immunogen:
Synthetic peptide: 3rd cytoplasmic domain of human muscarinic receptor M3, conjugated to KLH.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG