PIPA131348

AKAP3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA131348-Each-of-1 In Stock ₹ 47,015.22

PIPA131348 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

AKAP3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AKAP3

Gene Alias

A kinase (PRKA) anchor protein 3; AKAP 110; AKAP110; Akap3; AKAP-3; A-kinase anchor protein 110 kDa; A-kinase anchor protein 3; A-kinase anchor protein, 110kDa; A-kinase anchoring protein 3; Cancer/testis antigen 82; CT82; epididymis luminal protein 159; Fibrous Sheath Protein of 95 kDa; fibrousheathin 1; Fibrousheathin I; fibrousheathin-1; FSP95; HEL159; PRKA3; protein kinase A binding protein AKAP 110; Protein kinase A-anchoring protein 3; SOB1; Sperm oocyte-binding protein; sperm oocyte-binding protein 1

Host Species

Goat

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10566

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

O75969

Gene Symbols

AKAP3

Immunogen

synthetic peptide TPLQLLDWLMVNL, corresponding to C terminal amino acids 841-853 of Human AKAP3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX19046-PEP).
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The type II cAMP-dependent protein kinase (PKA) is a multifunctional kinase with a broad range of substrates
  • Specificity of PKA signaling is mediated by the compartmentalization of the kinase to specific sites within the cell
  • To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins, designated A-kinase anchoring proteins (AKAP)
  • AKAP 3, also known as AKAP 110, FSP95, PRKA3 and SOB1, binds both PKA and PDE4A and functions as a scaffolding protein in spermatozoa to regulate local cAMP concentrations and modulate sperm functions
  • Expression of AKAP 3 in normal tissues is restricted to the testis, where bicarbonate stimulates tyrosine phosphorylation of AKAP 3, thereby increasing its recruitment of PKA
  • AKAP-3 also exhibits high expression in patients with epithelial ovarian cancer (EOC)
  • It demonstrates tumor-restricted expression and appears to be associated with worse overall survival, which make AKAP 3 a potential target for antigen-specific immunotherapy in EOC.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA131348

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Antigen:
AKAP3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKAP3

Gene Alias:
A kinase (PRKA) anchor protein 3; AKAP 110; AKAP110; Akap3; AKAP-3; A-kinase anchor protein 110 kDa; A-kinase anchor protein 3; A-kinase anchor protein, 110kDa; A-kinase anchoring protein 3; Cancer/testis antigen 82; CT82; epididymis luminal protein 159; Fibrous Sheath Protein of 95 kDa; fibrousheathin 1; Fibrousheathin I; fibrousheathin-1; FSP95; HEL159; PRKA3; protein kinase A binding protein AKAP 110; Protein kinase A-anchoring protein 3; SOB1; Sperm oocyte-binding protein; sperm oocyte-binding protein 1

Host Species:
Goat

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10566

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O75969

Gene Symbols:
AKAP3

Immunogen:
synthetic peptide TPLQLLDWLMVNL, corresponding to C terminal amino acids 841-853 of Human AKAP3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA131438

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Antigen:
Phospho-MDM2 (Ser185)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MDM2

Gene Alias:
1700007J15Rik; AA415488; ACTFS; double minute 2; double minute 2 protein; double minute 2, human homolog of; p53-binding protein; E3 ubiquitin-protein ligase Mdm2; Hdm2; HDMX; HGNC:6973; human homolog of; MDM2; Mdm-2; MDM2 oncogene, E3 ubiquitin protein ligase; Mdm2 p53 binding protein homolog; MDM2 proto-oncogene; MDM2 proto-oncogene, E3 ubiquitin protein ligase; MDM2 variant FB28; Mdm2, p53 E3 ubiquitin protein ligase homolog; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; MGC5370; MGC71221; oncoprotein Mdm2; OTTHUMP00000183490; OTTHUMP00000183492; OTTHUMP00000183494; OTTHUMP00000183495; OTTHUMP00000183496; OTTHUMP00000183497; p53 E3 ubiquitin protein ligase; p53-binding protein Mdm2; RING-type E3 ubiquitin transferase Mdm2; transformed mouse 3T3 cell double minute 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17246, 314856, 4193

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P23804, Q00987

Gene Symbols:
MDM2

Immunogen:
synthetic peptide HRKRRRSLSFDPSLGLCEL, corresponding to amino acids 177-198 of Mouse MDM2.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA131456

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Antigen:
MSC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MSC

Gene Alias:
ABF1; ABF-1; Activated B-cell factor 1; activated B-cell factor 1, homolog of mouse musculin; activated B-cell factor-1; bHLHa22; Class A basic helix-loop-helix protein 22; Msc; Musculin; myogenic repressor; Myor

Host Species:
Goat

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
9242

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O60682

Gene Symbols:
MSC

Immunogen:
Peptide with sequence PLKSDWNSLDGIIR, from C-Terminus of the protein sequence according to NP_005089

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA131495

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Antigen:
GRB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRB2

Gene Alias:
AA408164; abundant SRC homology; adapter protein GRB2; Adapter protein GRB2-A; ASH; ASH protein; EGFRBP-GRB2; epidermal growth factor receptor-binding protein GRB2; grb2; grb2.L; grb2-a; grb2-b; Grb3-3; growth factor receptor bound protein 2; growth factor receptor bound protein 2 L homeolog; growth factor receptor-bound protein 2; Growth factor receptor-bound protein 2-A; growth factor receptor-bound protein 3; HT027; hypothetical protein LOC535298; MST084; MSTP084; NCKAP2; OTTHUMP00000166097; OTTHUMP00000166098; protein Ash; SH2/SH3 adapter GRB2; SH2/SH3 adapter GRB2-A; SH2/SH3 adaptor Grb2; XELAEV_18044055mg

Host Species:
Goat

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
100192436, 14784, 2885, 81504

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P62993, P62994, Q60631

Gene Symbols:
GRB2

Immunogen:
Peptide with sequence PRNYVTPVNRNV, from C Terminus of the protein sequence according to NP_002077

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG