PIPA3001

uPAR Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA3001-Each-of-1 In Stock ₹ 43,507.26

PIPA3001 - Each of 1

₹ 43,507.26

In Stock

Quantity

1

Base Price: ₹ 43,507.26

GST (18%): ₹ 7,831.307

Total Price: ₹ 51,338.567

Antigen

uPAR

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PLAUR

Gene Alias

Cd87; MO3; Monocyte activation antigen Mo3; Par; plasminogen activator urokinase receptor 3; plasminogen activator, urokinase receptor; PLAUR; Plaur3; sCD87; soluble CD87; uPAR; U-PAR; uPAR-2; uPAR-3; u-plasminogen activator receptor form 2; urinary plasminogen activator receptor 2; urinary plasminogen activator receptor 3; URKR; urokinase plasminogen activator receptor; urokinase plasminogen activator surface receptor; urokinase-type plasminogen activator (uPA) receptor; urokinase-type plasminogen activator receptor

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

5329

Content And Storage

-20°C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.

Q03405

Gene Symbols

PLAUR

Immunogen

Recombinant protein containing the D2D3 domain of human uPAR

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA3-001 detects uPAR in human samples and has been successfully used in Western blot and immunoprecipitation applications
  • The PA3-001 immunogen is a recombinant protein containing the D2D3 domain of human uPAR
  • The urokinase-type plasminogen activator receptor is a key molecule in the regulation of cell-surface plasminogen activation and plays an important role in many normal as well as pathologic processes
  • The human PLAUR cDNA encodes 335 amino acids including a predicted signal peptide of 22 residues and a hydrophobic C-terminal portion
  • It produces a highly glycosylated protein of about 50 kD in monocytes where it is anchored to the plasma membrane by glycosyl-phosphatidylinositol linkage
  • PLAUR, also known as UPAR, is directly associated with the carbohydrate-binding domain of SELL in the membrane of neutrophils, an association analogous to that between PLAUR and beta-2 integrins
  • PLAUR-mediated calcium mobilization is SELL dependent
  • UPAR mRNA levels correlate with the invasive potential of endometrial carcinomas and show a 33-fold increase in UPAR mRNA levels in advanced clinical stage endometrial tumors compared with normal endometrial tissue
  • Furthermore, the increase in UPAR mRNA levels correlated linearly with the progression of disease stage
  • UPAR protein expressioin correlated positively with rate of recurrence and mortality in patients with endometrial cancer
  • UPAR appears to be a useful prognostic marker for advanced endometrial cancer.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA3001

--


Antigen:
uPAR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLAUR

Gene Alias:
Cd87; MO3; Monocyte activation antigen Mo3; Par; plasminogen activator urokinase receptor 3; plasminogen activator, urokinase receptor; PLAUR; Plaur3; sCD87; soluble CD87; uPAR; U-PAR; uPAR-2; uPAR-3; u-plasminogen activator receptor form 2; urinary plasminogen activator receptor 2; urinary plasminogen activator receptor 3; URKR; urokinase plasminogen activator receptor; urokinase plasminogen activator surface receptor; urokinase-type plasminogen activator (uPA) receptor; urokinase-type plasminogen activator receptor

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5329

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
Q03405

Gene Symbols:
PLAUR

Immunogen:
Recombinant protein containing the D2D3 domain of human uPAR

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA3002

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Antigen:
Endothelin 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EDN2

Gene Alias:
EDN 2; Edn2; EDN-2; endothelin 2; Endothelin isopeptide 2; endothelin-2; ET2; ET-2; PP ET-2; PPET2; preproendothelin 2; preproendothelin-2; RNEDN2S01; vasoactive intestinal contractor; vasoactive intestinal contractor peptide; VIC

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
1907

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
P20800

Gene Symbols:
EDN2

Immunogen:
KLH conjugated Cys-S-Abu-SSWLDKE-Abu-VYF-Abu-HLDIIW

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA3005

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Antigen:
GPR17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GPR17

Gene Alias:
AI853548; DKFZp686M18273; G protein-coupled receptor 17; Gpr17; gpr17 {ECO:0000312; G-protein coupled receptor 17; P2Y-like receptor; R12; RGD:1589785}; UDP/CysLT receptor; Uracil nucleotide/cysteinyl leukotriene receptor; Y12546; Z94155

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
2840

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q13304

Gene Symbols:
GPR17

Immunogen:
KLH conjugated Cys-SFEGKTNESSLSAKSEL

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Antigen:
GPR18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GPR18

Gene Alias:
EMBL:AAI28783.1}; G protein-coupled receptor 18; GPCRW; Gpr18; gpr18 {ECO:0000312; G-protein coupled receptor 18; NAGly receptor; N-arachidonyl glycine receptor; RP11-461N23.8

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
2841

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
Conc. Not Determined

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
Q14330

Gene Symbols:
GPR18

Immunogen:
KLH conjugated Cys-RKSFRSGSLRSLSNINSEML

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG