PIPA5100070

MAVS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5100070-Each-of-1 In Stock ₹ 43,592.82

PIPA5100070 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

MAVS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAVS

Gene Alias

CARD adapter inducing interferon beta; CARD adaptor inducing IFN-beta; Cardif; D430028G21Rik; IFN-B promoter stimulator 1; IFN-beta promoter stimulator-1; interferon beta promoter stimulator protein 1; interferon-beta promoter stimulator protein 1; IPS1; IPS-1; KIAA1271; MAVS; mitochondrial antiviral signaling protein; mitochondrial anti-viral signaling protein; mitochondrial antiviral-signaling protein; Putative NF-kappa-B-activating protein 031N; virus-induced signaling adapter; virus-induced signaling adaptor; virus-induced-signaling adapter; VISA

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

228607, 57506

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q7Z434, Q8VCF0

Gene Symbols

MAVS

Immunogen

A synthesized peptide derived from human MAVS(Accession Q7Z434), corresponding to amino acid residues G467-W517.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total VISA
  • Two distinct signaling pathways activate the host innate immunity against viral infection
  • One pathway is reliant on members of the Toll-like receptor (TLR) family while the other uses the RNA helicase RIG-I as a receptor for intracellular viral double-stranded RNA as a trigger for the immune response
  • MAVS is a mitochondrial membrane protein that was identified as a critical component in the IFN beta signaling pathways that recruits IRF-3 to RIG-I, leading to its activation and that of NF-kappa-B
  • MAVS is also thought to interact with other components of the innate immune pathway such as the TLR adapter protein TRIF, TRAF2 and TRAF6
  • MAVS also interacts with the IKK-alpha, IKK-beta and IKK-iota kinases through its C-terminal region
  • Cleavage of this region by the Hepatitis C virus (HCV) protease allows HCV to escape the host immune system
  • Multiple isoforms of MAVS are known to exist.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5100070

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Antigen:
MAVS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAVS

Gene Alias:
CARD adapter inducing interferon beta; CARD adaptor inducing IFN-beta; Cardif; D430028G21Rik; IFN-B promoter stimulator 1; IFN-beta promoter stimulator-1; interferon beta promoter stimulator protein 1; interferon-beta promoter stimulator protein 1; IPS1; IPS-1; KIAA1271; MAVS; mitochondrial antiviral signaling protein; mitochondrial anti-viral signaling protein; mitochondrial antiviral-signaling protein; Putative NF-kappa-B-activating protein 031N; virus-induced signaling adapter; virus-induced signaling adaptor; virus-induced-signaling adapter; VISA

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228607, 57506

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q7Z434, Q8VCF0

Gene Symbols:
MAVS

Immunogen:
A synthesized peptide derived from human MAVS(Accession Q7Z434), corresponding to amino acid residues G467-W517.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100072

--


Antigen:
MTO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTO1

Gene Alias:
2310039H01Rik; 5730419A02Rik; CGI02; CGI-02; COXPD10; homolog of yeast Mto1; LOW QUALITY PROTEIN: protein MTO1 homolog, mitochondrial; mitochondrial MTO1-3; mitochondrial translation optimization 1 homolog; mitochondrial translation optimization 1 homolog (S. cerevisiae); mitochondrial tRNA translation optimization 1; MTO1; Protein MTO1 homolog, mitochondrial

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25821, 300852, 68291

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q923Z3, Q9Y2Z2

Gene Symbols:
MTO1

Immunogen:
A synthesized peptide derived from human MTO1(Accession Q9Y2Z2), corresponding to amino acid residues C58-G108.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100073

--


Antigen:
NAPRT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NAPRT

Gene Alias:
9130210N20Rik; FHA-HIT-interacting protein; FHIP; hypothetical protein MGC77870; Naprt; Naprt1; NAPRTase; Nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase domain containing 1; nicotinate phosphoribosyltransferase domain-containing protein 1; nicotinate phosphoribosyltransferase; LOW QUALITY PROTEIN: nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase-like protein; nicotinic acid phosphoribosyltransferase; PP3856; zgc:77870

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
223646, 315085, 93100

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6XQN1, Q6XQN6, Q8CC86

Gene Symbols:
NAPRT

Immunogen:
A synthesized peptide derived from human NAPRT(Accession Q6XQN6), corresponding to amino acid residues A199-W249.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100076

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Antigen:
RCN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RCN2

Gene Alias:
AA408742; Calcium-binding protein ERC-55; E6-binding protein; E6BP; ERC55; ERC-55; RCN2; reticulocalbin 2; reticulocalbin 2, EF-hand calcium binding domain; reticulocalbin 2, EF-hand calcium binding domain (endoplasmic reticulum calcium-binding protein, 55kD); reticulocalbin-2; taipoxin-associated calcium binding protein 49; taipoxin-associated calcium-binding protein 49; TCBP49; TCBP-49

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26611, 29218, 5955

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q14257, Q62703, Q8BP92

Gene Symbols:
RCN2

Immunogen:
A synthesized peptide derived from human RCN2(Accession Q14257), corresponding to amino acid residues L277-L317.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG