PIPA5100378
AFAP1L2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5100378-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5100378 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
AFAP1L2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AFAP1L2
Gene Alias
actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
226250, 292130, 84632
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q5DTU0, Q8N4X5
Gene Symbols
AFAP1L2
Immunogen
A synthesized peptide derived from human AFAP1L2(Accession Q8N4X5), corresponding to amino acid residues N67-T117.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total AFAP1L2
- AFAP1L2, also known as XB130, is structurally similar to actin-filament-associated protein (AFAP), containing several SH2- and SH3-binding motifs, two pleckstrin homology domains, a coiled-coil region, and many potential phosphorylation sites
- It interacts with and is phosphorylated by c-Src tyrosine kinase
- Suppression of AFAP1L2 via siRNA reduced Src activity, IL-8 production, EGF-induced phosphorylation of Akt and GSK3beta, and altered cell cycles in human lung epithelial cells suggesting that AFAP1L2 plays a role as an adaptor in the regulation of Src signal transduction and multiple cellular functions
- Recent experiments have shown that AFAP1L2 is highly expressed in thyroid and is the substrate RET/PTC kinase, a thyroid-specific kinase that plays a pathogenic role in papillary thyroid cancer
- Down-regulation of AFAP1L2 in these cancer cells reduced Akt activity, inhibiting cell-cycle progression and cancer cell survival in suspension, indicating that AFAP1L2 may be a valuable target in thyroid cancer therapy
- At least four isoforms of AFAP1L2 are known to exist.
Compare Similar Items
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Antigen: AFAP1L2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AFAP1L2
Gene Alias: actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 226250, 292130, 84632
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q5DTU0, Q8N4X5
Gene Symbols: AFAP1L2
Immunogen: A synthesized peptide derived from human AFAP1L2(Accession Q8N4X5), corresponding to amino acid residues N67-T117.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AFAP1L2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AFAP1L2
Gene Alias:
actin filament associated protein 1 like 2; actin filament associated protein 1-like 2; actin filament-associated protein 1-like 2; Afap1l2; AFAP1-like protein 2; AU041783; C86904; CTB-1144G6.4; CTB-1144G6.6; KIAA1914; mKIAA1914; phosphatidylinositol 3-kinase-associated protein; RGD1310668; XB130
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
226250, 292130, 84632
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5DTU0, Q8N4X5
Gene Symbols:
AFAP1L2
Immunogen:
A synthesized peptide derived from human AFAP1L2(Accession Q8N4X5), corresponding to amino acid residues N67-T117.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: AFMID
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AFMID
Gene Alias: 9030621K19Rik; AFMID; Ammd; Arylformamidase; FKF; formylase; formylkynureninase; hypothetical protein LOC550372; im:7148587; Kf; KFA; KFase; kynurenine formamidase; N-formylkynurenine formamidase; probable arylformamidase; zgc:112472
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 125061, 71562
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q63HM1, Q8K4H1
Gene Symbols: AFMID
Immunogen: A synthesized peptide derived from human AFMID(Accession Q63HM1), corresponding to amino acid residues T142-L192.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
AFMID
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AFMID
Gene Alias:
9030621K19Rik; AFMID; Ammd; Arylformamidase; FKF; formylase; formylkynureninase; hypothetical protein LOC550372; im:7148587; Kf; KFA; KFase; kynurenine formamidase; N-formylkynurenine formamidase; probable arylformamidase; zgc:112472
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
125061, 71562
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q63HM1, Q8K4H1
Gene Symbols:
AFMID
Immunogen:
A synthesized peptide derived from human AFMID(Accession Q63HM1), corresponding to amino acid residues T142-L192.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: AIPL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AIPL1
Gene Alias: A930007I01Rik; AIPL1; AIPL2; aryl hydrocarbon receptor interacting protein like 1; aryl hydrocarbon receptor interacting protein-like 1; aryl hydrocarbon receptor-interacting protein-like 1; aryl-hydrocarbon interacting protein-like 1; aryl-hydrocarbon-interacting protein-like 1; EGK_08083; LCA4
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114230, 23746, 59110
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q924K1, Q9JLG9, Q9NZN9
Gene Symbols: AIPL1
Immunogen: A synthesized peptide derived from human AIPL1(Accession Q9NZN9), corresponding to amino acid residues P339-H384.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AIPL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AIPL1
Gene Alias:
A930007I01Rik; AIPL1; AIPL2; aryl hydrocarbon receptor interacting protein like 1; aryl hydrocarbon receptor interacting protein-like 1; aryl hydrocarbon receptor-interacting protein-like 1; aryl-hydrocarbon interacting protein-like 1; aryl-hydrocarbon-interacting protein-like 1; EGK_08083; LCA4
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114230, 23746, 59110
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q924K1, Q9JLG9, Q9NZN9
Gene Symbols:
AIPL1
Immunogen:
A synthesized peptide derived from human AIPL1(Accession Q9NZN9), corresponding to amino acid residues P339-H384.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: AJUBA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AJUBA
Gene Alias: AJUBA; ajuba homolog; ajuba LIM protein; Ajuba protein; JUB; jub, ajuba homolog; LIM domain-containing protein ajuba; protein ajuba
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16475, 84962, 85265
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q5U2Z2, Q91XC0, Q96IF1
Gene Symbols: AJUBA
Immunogen: A synthesized peptide derived from human AJUBA(Accession Q96IF1), corresponding to amino acid residues S202-L252.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AJUBA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AJUBA
Gene Alias:
AJUBA; ajuba homolog; ajuba LIM protein; Ajuba protein; JUB; jub, ajuba homolog; LIM domain-containing protein ajuba; protein ajuba
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16475, 84962, 85265
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q5U2Z2, Q91XC0, Q96IF1
Gene Symbols:
AJUBA
Immunogen:
A synthesized peptide derived from human AJUBA(Accession Q96IF1), corresponding to amino acid residues S202-L252.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG