PIPA5100695

TSEN2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5100695-Each-of-1 In Stock ₹ 44,705.10

PIPA5100695 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TSEN2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Tsen2

Gene Alias

AU067695; HsSen2; PCH2B; RGD1309946; SEN2; SEN2L; tRNA splicing endonuclease 2 homolog (S. cerevisiae); tRNA splicing endonuclease subunit 2; tRNA-intron endonuclease Sen2; tRNA-intron nuclease 2; tRNA-splicing endonuclease subunit Sen2; Tsen2; TSEN2 tRNA splicing endonuclease subunit

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

80746

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8NCE0

Gene Symbols

Tsen2

Immunogen

A synthesized peptide derived from human TSEN2(Accession Q8NCE0), corresponding to amino acid residues H347-R397.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total TSEN2
  • Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA
  • It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron
  • The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini
  • There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body
  • Isoform 1 probably carries the active site for 5'-splice site cleavage
  • The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre- mRNA 3'-end processing factors, establishing a link between pre- tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events
  • Isoform 2 is responsible for processing a yet unknown RNA substrate
  • The complex containing isoform 2 is not able to cleave pre-tRNAs properly, although it retains endonucleolytic activity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5100695

--


Antigen:
TSEN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Tsen2

Gene Alias:
AU067695; HsSen2; PCH2B; RGD1309946; SEN2; SEN2L; tRNA splicing endonuclease 2 homolog (S. cerevisiae); tRNA splicing endonuclease subunit 2; tRNA-intron endonuclease Sen2; tRNA-intron nuclease 2; tRNA-splicing endonuclease subunit Sen2; Tsen2; TSEN2 tRNA splicing endonuclease subunit

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80746

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8NCE0

Gene Symbols:
Tsen2

Immunogen:
A synthesized peptide derived from human TSEN2(Accession Q8NCE0), corresponding to amino acid residues H347-R397.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100696

--


Antigen:
USP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP1

Gene Alias:
Deubiquitinating enzyme 1; EMBL:AAH92574.1, ECO:0000312; hUBP; MGC137005 protein; RGD:1306461}; ubiquitin carboxyl terminal hydrolase 1; ubiquitin carboxyl-terminal hydrolase 1; ubiquitin carboxyl-terminal hydrolase 1-like protein; ubiquitin specific peptidase 1; ubiquitin specific processing protease 1; ubiquitin specific protease 1; ubiquitin thioesterase 1; ubiquitin thiolesterase 1; ubiquitin-specific-processing protease 1; UBP; usp1; usp1 {ECO:0000312

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7398

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O94782

Gene Symbols:
USP1

Immunogen:
A synthesized peptide derived from human USP1(Accession O94782), corresponding to amino acid residues P687-V737.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5100697

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Antigen:
USP37

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Usp37

Gene Alias:
4932415L06Rik; C330008N13Rik; Deubiquitinating enzyme 37; Kiaa1594; tmp_locus_50; ubiquitin carboxyl-terminal hydrolase 37; ubiquitin specific peptidase 37; ubiquitin specific peptidase 37-like; ubiquitin specific protease 37; ubiquitin thioesterase 37; ubiquitin thiolesterase 37; ubiquitin-specific-processing protease 37; USP37

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100361658, 57695

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q86T82

Gene Symbols:
Usp37

Immunogen:
A synthesized peptide derived from human USP37(Accession Q86T82), corresponding to amino acid residues P760-E810.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5100700

--


Antigen:
VPS4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VPS4B

Gene Alias:
8030489C12Rik; cell migration-inducing 1; cell migration-inducing gene 1 protein; MIG1; Protein SKD1; SKD1; SKD1B; Suppressor of K(+) transport growth defect 1; suppressor of K+ transport defect 1; vacuolar protein sorting 4 homolog B; vacuolar protein sorting 4 homolog B (S. cerevisiae); vacuolar protein sorting 4B; vacuolar protein sorting 4b (yeast); vacuolar protein sorting-associated protein 4B; VPS42; VPS4-2; Vps4b

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20479, 360834, 9525

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75351, P46467

Gene Symbols:
VPS4B

Immunogen:
A synthesized peptide derived from human VPS4B(Accession O75351), corresponding to amino acid residues N78-R128.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG