PIPA5100741

GADD45B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5100741-Each-of-1 In Stock ₹ 46,330.74

PIPA5100741 - Each of 1

₹ 46,330.74

In Stock

Quantity

1

Base Price: ₹ 46,330.74

GST (18%): ₹ 8,339.533

Total Price: ₹ 54,670.273

Antigen

GADD45B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GADD45B

Gene Alias

AI323528; DKFZP566B133; Gadd45b; GADD45BETA; growth arrest and DNA damage inducible beta; growth arrest and DNA damage-inducible protein GADD45 beta; growth arrest and DNA-damage-inducible 45 beta; growth arrest and DNA-damage-inducible protein GADD45 beta; growth arrest and DNA-damage-inducible, beta; MYD118; myeloid differentiation primary response; myeloid differentiation primary response gene 118; myeloid differentiation primary response protein MyD118; Negative growth regulatory protein MyD118; Unknown (protein for MGC:138134)

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17873, 299626, 4616

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O75293, P22339

Gene Symbols

GADD45B

Immunogen

A synthesized peptide derived from human GADD45B(Accession O75293), corresponding to amino acid residues L117-R160.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total GADD45B
  • Cellcycle progression issubject to arrest at G1 and G2 checkpointsin response to DNA damage, presumablyto allow time for DNA repair prior to entryinto S andMphase, respectively
  • The p53 tumorsuppressor isrequired for one such G1 checkpoint and functionsto upregulate expression of GADD 45 and p21
  • GADD 45 binds both Cdks and PCNA, a protein involved in DNA replication and repair
  • GADD 45 stimulates DNA excision repair in vitro and inhibits entry ofcellsinto S phase
  • Thus, it has been suggested that GADD 45 mayserve as a link between the p53-dependentcellcycle checkpoint and DNA repair
  • GADD 45-like proteins, GADD 45 beta and GADD 45 gamma, have been shown to be induced by environmentalstresses
  • GADD 45 beta and GADD 45 gamma are thought to induce p38/JNK activation via MEKK4 activation.

Compare Similar Items

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Img

Thermo Scientific

PIPA5100741

--


Antigen:
GADD45B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GADD45B

Gene Alias:
AI323528; DKFZP566B133; Gadd45b; GADD45BETA; growth arrest and DNA damage inducible beta; growth arrest and DNA damage-inducible protein GADD45 beta; growth arrest and DNA-damage-inducible 45 beta; growth arrest and DNA-damage-inducible protein GADD45 beta; growth arrest and DNA-damage-inducible, beta; MYD118; myeloid differentiation primary response; myeloid differentiation primary response gene 118; myeloid differentiation primary response protein MyD118; Negative growth regulatory protein MyD118; Unknown (protein for MGC:138134)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17873, 299626, 4616

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75293, P22339

Gene Symbols:
GADD45B

Immunogen:
A synthesized peptide derived from human GADD45B(Accession O75293), corresponding to amino acid residues L117-R160.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5100742

--


Antigen:
GADD45G

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GADD45G

Gene Alias:
AI327420; C86281; CR6; Cytokine-responsive protein CR6; DDIT2; DDIT-2; DNA damage-inducible transcript 2 protein; GADD45G; GADD45gamma; GADD45-gamma; gadd-related protein, 17 kD; growth arrest and DNA damage inducible; growth arrest and DNA damage inducible gamma; growth arrest and DNA damage-inducible protein GADD45 gamma; growth arrest and DNA-damage-inducible 45 gamma; growth arrest and DNA-damage-inducible protein GADD45 gamma; growth arrest and DNA-damage-inducible, gamma; GRP17; OIG37; RP11-260L6.1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10912, 23882, 291005

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O95257, Q9WTQ7, Q9Z111

Gene Symbols:
GADD45G

Immunogen:
A synthesized peptide derived from human GADD45G(Accession O95257), corresponding to amino acid residues A103-P153.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5100744

--


Antigen:
Granzyme M

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GZMM

Gene Alias:
granzyme M; granzyme M (lymphocyte met-ase 1); GZMM; Hu-Met-1; Lmet1; lymphoctye Met-ase 1; lymphocyte met-ase 1; MET1; Met-1 serine protease; Met-ase; MMET-1; natural killer cell granular protease; RNK-Met-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16904, 3004

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P51124

Gene Symbols:
GZMM

Immunogen:
A synthesized peptide derived from human GZMM(Accession P51124), corresponding to amino acid residues G157-S207.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5100745

--


Antigen:
Laminin alpha-5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LAMA5

Gene Alias:
[a]5; AA408760; AA408762; AI853660; KIAA0533; KIAA1907; LAMA5; laminin alpha-5 chain; laminin subunit alpha 5; laminin subunit alpha-5; laminin, alpha 5; laminin-10 subunit alpha; Laminin-11 subunit alpha; laminin-15 subunit alpha; laminin-511; mKIAA0533; RP11-157P1.6

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16776, 3911

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O15230, Q61001

Gene Symbols:
LAMA5

Immunogen:
A synthesized peptide derived from human LAMA5(Accession O15230), corresponding to amino acid residues V512-C562.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG