PIPA5100795

WWTR1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5100795-Each-of-1 In Stock ₹ 44,705.10

PIPA5100795 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

WWTR1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

WWTR1

Gene Alias

2310058J06Rik; 2610021I22Rik; C78399; DKFZp586I1419; FLJ27004; FLJ45718; Tafazzin; TAZ; transcriptional coactivator with PDZ binding motif; transcriptional co-activator with PDZ-binding motif; transcriptional coactivator with PDZ-binding motif; transcriptional co-activator with PDZ-binding motif (TA)Z; transcriptional co-activator with PDZ-binding motif (TAZ); WW domain containing transcription regulator 1; WW domain-containing transcription regulator protein 1; Wwtr1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25937, 97064

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9EPK5, Q9GZV5

Gene Symbols

WWTR1

Immunogen

A synthesized peptide derived from human WWTR1(Accession Q9GZV5), corresponding to amino acid residues R63-L113.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total TAZ
  • WW domain-containing transcription regulator protein 1 (WWTR1) is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor supression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1
  • In turn, MOB1 phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation
  • WWTR1 regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex
  • WWTR1 also regulates embryonic stem-cell self-renewal and promotes cell proliferation and epithelial-mesenchymal transition.

Compare Similar Items

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Img

Thermo Scientific

PIPA5100795

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Antigen:
WWTR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WWTR1

Gene Alias:
2310058J06Rik; 2610021I22Rik; C78399; DKFZp586I1419; FLJ27004; FLJ45718; Tafazzin; TAZ; transcriptional coactivator with PDZ binding motif; transcriptional co-activator with PDZ-binding motif; transcriptional coactivator with PDZ-binding motif; transcriptional co-activator with PDZ-binding motif (TA)Z; transcriptional co-activator with PDZ-binding motif (TAZ); WW domain containing transcription regulator 1; WW domain-containing transcription regulator protein 1; Wwtr1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25937, 97064

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9EPK5, Q9GZV5

Gene Symbols:
WWTR1

Immunogen:
A synthesized peptide derived from human WWTR1(Accession Q9GZV5), corresponding to amino acid residues R63-L113.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100796

--


Antigen:
TSPYL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSPYL2

Gene Alias:
CASK interacting nucleosome assembly protein; CASK-interacting nucleosome assembly protein; CDA1; Cell division autoantigen 1; cell division autoantigen 1 nucleolar protein; CINAP; CTCL; CTCL tumor antigen se20-4; CTCL-associated antigen se20-4; Cutaneous T-cell lymphoma-associated antigen se20-4; cutaneous T-cell lymphoma-associated tumor antigen se20-4; DENTT; differentially expressed nucleolar TGF-beta1 target; differentially-expressed nucleolar TGF-beta1 target protein; DXBwg1396e; DXHXS1008E; E130307F10Rik; HRIHFB2216; NP79; nuclear protein of 79 kDa; nucleolar TGF-beta1 target protein; RGD1563283; RP1-290F12.2; SE204; testis-specific protein Y encoded-like 2; testis-specific Y-encoded-like protein 2; TSPX; TSPY like 2; Tspyl2; TSPY-like 2; TSPY-like protein 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
302612, 52808, 64061

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q7TQI8, Q9H2G4

Gene Symbols:
TSPYL2

Immunogen:
A synthesized peptide derived from human TSPYL2(Accession Q9H2G4), corresponding to amino acid residues I452-H502.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100797

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Antigen:
MANSC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MANSC1

Gene Alias:
9130403P13Rik; LOH12CR3; Loss of heterozygosity 12 chromosomal region 3 protein; MANSC domain containing 1; MANSC domain-containing protein 1; Mansc1; UNQ316/PRO361

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54682, 690606

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9H8J5

Gene Symbols:
MANSC1

Immunogen:
A synthesized peptide derived from human MANSC1(Accession Q9H8J5), corresponding to amino acid residues P321-S371.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5100799

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Antigen:
MED20

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MED20

Gene Alias:
1110011O05Rik; 2410115I17Rik; AU018348; hTRFP; Med20; Mediator complex subunit 20; mediator of RNA polymerase II transcription subunit 20; PRO0213; Trf (TATA binding protein-related factor)-proximal homolog; Trf (TATA binding protein-related factor)-proximal protein homolog; TRFP; TRF-proximal protein homolog; ubiquitin specific protease 49; Usp49

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
316209, 56771, 9477

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q5XIE9, Q9H944, Q9R0X0

Gene Symbols:
MED20

Immunogen:
A synthesized peptide derived from human MED20(Accession Q9H944), corresponding to amino acid residues K27-A77.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG