PIPA5101276

ATF5 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5101276-Each-of-1 In Stock ₹ 44,705.10

PIPA5101276 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ATF5

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Atf5

Gene Alias

activating transcription factor 5; Activating transcription factor 5-alpha/beta; activating transcription factor 7; activating transcription factor X; AFTA; ATF5; Atf7; Atfx; BZIP protein ATF7; cAMP-dependent transcription factor ATF-5; Cyclic AMP-dependent transcription factor ATF-5; FLJ34666; HMFN0395; NAP1; NRIF3-associated protein; ODA-10; Transcription factor ATFx; transcription factor-like protein ODA-10

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

107503, 22809, 282840

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O70191, Q6P788, Q9Y2D1

Gene Symbols

Atf5

Immunogen

A synthesized peptide derived from human ATF5(Accession Q9Y2D1), corresponding to amino acid residues A35-P85.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total ATF5
  • ATF5 is a protein coding gene
  • Transcription factor that either stimulates or represses gene transcription through binding of different DNA regulatory elements such as cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), ATF5-specific response element (ARE) (consensus: 5'-C[CT]TCT[CT]CCTT[AT]-3') but also the amino acid response element (AARE), present in many viral and cellular promoters
  • Critically involved, often in a cell type-dependent manner, in cell survival, proliferation, and differentiation
  • Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4
  • Important regulator of the cerebral cortex formation, functions in cerebral cortical neuroprogenitor cells to maintain proliferation and to block differentiation into neurons
  • Must be down-regulated in order for such cells to exit the cycle and differentiate
  • Participates in the pathways by which SHH promotes cerebellar granule neuron progenitor cells proliferation
  • Critical for survival of mature olfactory sensory neurons (OSN), directs expression of OSN-specific genes
  • May be involved in osteogenic differentiation
  • Promotes cell proliferation and survival by inducing the expression of EGR1 sinergistically with ELK1
  • Once acetylated by EP300, binds to ARE sequences on target genes promoters, such as BCL2 and EGR1
  • Plays an anti-apoptotic role through the transcriptional regulation of BCL2, this function seems to be cell type-dependent
  • Cooperates with NR1I3/CAR in the transcriptional activation of CYP2B6 in liver
  • In hepatic cells, represses CRE-dependent transcription and inhibits proliferation by blocking at G2/M phase
  • May act as a negative regulator of IL1B transduction pathway in liver
  • Upon IL1B stimulus, cooperates with NLK to activate the transactivation activity of C/EBP subfamily members
  • Besides its function of transcription factor, acts as a cofactor of CEBPB to activate CEBPA and promote adipocyte differentiation
  • Regulates centrosome dynamics in a cell-cycle- and centriole-age-dependent manner
  • Forms 9-foci symmetrical ring scaffold around the mother centriole to control centrosome function and the interaction between centrioles and pericentriolar material.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5101276

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Antigen:
ATF5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atf5

Gene Alias:
activating transcription factor 5; Activating transcription factor 5-alpha/beta; activating transcription factor 7; activating transcription factor X; AFTA; ATF5; Atf7; Atfx; BZIP protein ATF7; cAMP-dependent transcription factor ATF-5; Cyclic AMP-dependent transcription factor ATF-5; FLJ34666; HMFN0395; NAP1; NRIF3-associated protein; ODA-10; Transcription factor ATFx; transcription factor-like protein ODA-10

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107503, 22809, 282840

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O70191, Q6P788, Q9Y2D1

Gene Symbols:
Atf5

Immunogen:
A synthesized peptide derived from human ATF5(Accession Q9Y2D1), corresponding to amino acid residues A35-P85.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5101279

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Antigen:
SPIN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPIN1

Gene Alias:
30000 Mr metaphase complex; OCR; Ovarian cancer-related protein; SPIN; Spin1; spindlin 1; Spindlin1; spindlin-1; SSEC P; TDRD24

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10927, 20729, 361217

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q4V8J7, Q61142, Q9Y657

Gene Symbols:
SPIN1

Immunogen:
A synthesized peptide derived from human SPIN1(Accession Q9Y657), corresponding to amino acid residues A17-G67.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5101280

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Antigen:
14-3-3 eta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
YWHAH

Gene Alias:
14-3-3 eta; 14-3-3 protein eta; 14-3-3 protein eta-subtype; 14-3-3e; 1433F; fb93e02; Protein AS1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; wu:fb51h04; wu:fb93e02; YWHA1; YWHA114-3-3 eta; ywhag; YWHAH; zgc:63883; zgc:63883 protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22629, 25576, 7533

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P68510, P68511, Q04917

Gene Symbols:
YWHAH

Immunogen:
A synthesized peptide derived from human YWHAH(Accession Q04917), corresponding to amino acid residues K127-L177.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5101282

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Antigen:
HTR6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HTR6

Gene Alias:
5-HT6; 5-HT-6; 5-HT6 receptor; 5-HT6R; 5-hydroxytryptamine (serotonin) receptor 6; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; 5-hydroxytryptamine receptor 6; Htr6; Serotonin receptor 6; ST-B17

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15565, 3362, 64354

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P31388, P50406, Q9R1C8

Gene Symbols:
HTR6

Immunogen:
A synthesized peptide derived from human HTR6(Accession P50406), corresponding to amino acid residues L225-G275.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG