PIPA5101153

FOXC1/FOXC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5101153-Each-of-1 In Stock ₹ 44,705.10

PIPA5101153 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

FOXC1/FOXC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FOXC1

Gene Alias

ARA; BF-3; Brain factor 3; ch; congenital hydrocephalus; Fkh1; fkh-1; Fkh14; FKHL14; FKHL7; forkhead box C1; forkhead box C1 protein; forkhead box C2; forkhead box C2 (MFH-1 mesenchyme forkhead 1); forkhead box C2 (MFH-1, mesenchyme forkhead 1); forkhead box protein C1; Forkhead box protein C2; forkhead homolog 14; forkhead, Drosophila, homolog-like 14; forkhead, drosophila, homolog-like 7; forkhead/winged helix-like transcription factor 7; forkhead-related activator 3; forkhead-related protein FKHL14; Forkhead-related protein FKHL7; forkhead-related transcription factor 3; Foxc1; Foxc2; FREAC3; FREAC-3; frkhda; Hfhbf3; HFH-BF-3; IGDA; IHG1; IRID1; LD; mesenchyme fork head protein 1; mesenchyme forkhead 1; mesoderm/mesenchyme forkhead 1; Mf1; MF-1; Mf4; MFH1; MFH-1; MFH-1 protein; MFH-1,mesenchyme forkhead 1; myeloid factor-delta; RIEG3; Transcription factor FKH-1; transcription factor FKH-14

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14234, 171356, 17300, 2296, 2303, 364706

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q12948, Q61572, Q61850, Q63246, Q99958

Gene Symbols

FOXC1, FOXC2

Immunogen

A synthesized peptide derived from human FOXC1(Accession Q12948), corresponding to amino acid residues N118-L168.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total FOXC1/2
  • The forkhead transcription factor genes FOXC1 (Mf1) and FOXC2 (Mfh1) interact with the Notch signaling pathway and are required for the prepatterning of anterior and posterior domains in the presumptive somites through a putative Notch/Delta/Mesp regulatory loop
  • The genes have similar, dose-dependent functions, and compensate for each other in the early development of the heart, blood vessels and somites
  • Both FOXC1 and FOXC2 are expressed in the mesenchyme from which the ocular drainage structures derive
  • FOXC1 and FOXC2 also interact in kidney and heart development
  • Mutations in the FOXC1 gene result in Axenfeld-Rieger malformations of the anterior segment of the eye and lead to an increased susceptibility of glaucoma, including juvenile glaucoma
  • Functional regions in FOXC1 are required for nuclear localization and transcriptional regulation
  • Specifically, two regions in the FOXC1 forkhead domain, one rich in basic amino acid residues, and a second, highly conserved among all FOX proteins, are necessary for nuclear localization of the FOXC1 protein.

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Thermo Scientific

PIPA5101153

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Antigen:
FOXC1/FOXC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXC1

Gene Alias:
ARA; BF-3; Brain factor 3; ch; congenital hydrocephalus; Fkh1; fkh-1; Fkh14; FKHL14; FKHL7; forkhead box C1; forkhead box C1 protein; forkhead box C2; forkhead box C2 (MFH-1 mesenchyme forkhead 1); forkhead box C2 (MFH-1, mesenchyme forkhead 1); forkhead box protein C1; Forkhead box protein C2; forkhead homolog 14; forkhead, Drosophila, homolog-like 14; forkhead, drosophila, homolog-like 7; forkhead/winged helix-like transcription factor 7; forkhead-related activator 3; forkhead-related protein FKHL14; Forkhead-related protein FKHL7; forkhead-related transcription factor 3; Foxc1; Foxc2; FREAC3; FREAC-3; frkhda; Hfhbf3; HFH-BF-3; IGDA; IHG1; IRID1; LD; mesenchyme fork head protein 1; mesenchyme forkhead 1; mesoderm/mesenchyme forkhead 1; Mf1; MF-1; Mf4; MFH1; MFH-1; MFH-1 protein; MFH-1,mesenchyme forkhead 1; myeloid factor-delta; RIEG3; Transcription factor FKH-1; transcription factor FKH-14

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14234, 171356, 17300, 2296, 2303, 364706

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q12948, Q61572, Q61850, Q63246, Q99958

Gene Symbols:
FOXC1, FOXC2

Immunogen:
A synthesized peptide derived from human FOXC1(Accession Q12948), corresponding to amino acid residues N118-L168.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101157

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Antigen:
JIP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK8IP2

Gene Alias:
3230402N03Rik; AI847694; AW049958; C-Jun-amino-terminal kinase-interacting protein 2; homologous to mouse JIP-1; IB 2; Ib2; IB-2; Islet brain 2; islet-brain 2; islet-brain-2; JIP 2; JIP2; JIP-2; JNK MAP kinase scaffold protein 2; JNK MAP kinase scaffold protein JIP2; JNK-interacting protein 2; Mapk8ip2; mitogen activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8-interacting protein 2; PRKM8IPL; R75148; si:dkey-180h12.2; si:dkey-181m21.1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23542, 315220, 561262, 60597

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
G3V9M2, Q13387, Q9ERE9

Gene Symbols:
MAPK8IP2

Immunogen:
A synthesized peptide derived from human MAPK8IP2(Accession Q13387), corresponding to amino acid residues V581-V631.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101159

--


Antigen:
FOXE3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXE3

Gene Alias:
dyl; dysgenetic lens; FKHL12; forkhead box E3; forkhead box protein E3; forkhead, drosophila, homolog-like 12; forkhead-related protein FKHL12; Forkhead-related transcription factor 8; Foxe3; FREAC8; FREAC-8; Hepatocyte nuclear factor 3 forkhead homolog 7; HFH7; HFH-7; HNF3; rct; Rinshoken cataract

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171302, 2301, 30923

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q13461, Q63250, Q9QY14

Gene Symbols:
FOXE3

Immunogen:
A synthesized peptide derived from human FOXE3(Accession Q13461), corresponding to amino acid residues L84-R134.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5101160

--


Antigen:
TOP3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Top3a

Gene Alias:
DNA topoisomerase 3-alpha; DNA topoisomerase III alpha; Top IIIa; TOP3; TOP3A; topo III-alpha; topoisomerase (DNA) 3 alpha; topoisomerase (DNA) III alpha; topoisomerase 3 alpha; ZGRF7; zinc finger, GRF-type containing 7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21975, 7156

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O70157, Q13472

Gene Symbols:
Top3a

Immunogen:
A synthesized peptide derived from human TOP3A(Accession Q13472), corresponding to amino acid residues D953-R1001.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG