PIPA5102347

AMBRA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102347-Each-of-1 In Stock ₹ 44,705.10

PIPA5102347 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

AMBRA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AMBRA1

Gene Alias

2310079H06Rik; A130023A14; AA474864; activating molecule in beclin-1-regulated autophagy; activating molecule in Beclin1-regulated autophagy; activating molecule in BECN1-regulated autophagy protein 1; AMBRA1; autophagy and beclin 1 regulator 1; autophagy/beclin 1 regulator 1; autophagy/beclin-1 regulator 1; AV021921; D030051N19Rik; DCAF3; DDB1 and CUL4 associated factor 3; hypothetical protein; hypothetical protein LOC517263; ischemia related factor NYW-1; Kiaa1736; mKIAA1736; Nyw1; WD repeat domain 94; WDR94

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

228361, 55626, 59319

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

A2AH22, Q9C0C7

Gene Symbols

AMBRA1

Immunogen

A synthesized peptide derived from human AMBRA1(Accession Q9C0C7), corresponding to amino acid residues E1046-A1096.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total AMBRA1
  • Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
  • It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
  • Beclin-1, a principal regulator of autophagosome formation, is in turn regulated by Ambra1
  • Ambra1 associates with Beclin-1 through a region near its center as determined by yeast two-hybrid assay
  • Null mutations in this gene in mice resulted in embryonic lethality with severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic death
  • Furthermore, down-regulation of Ambra1 in cultured cells though RNA interference decreased the level of rapamycin- and nutrient starvation-induced autophagy
  • Multiple isoforms of Ambra1 are known to exist.

Compare Similar Items

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Thermo Scientific

PIPA5102347

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Antigen:
AMBRA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AMBRA1

Gene Alias:
2310079H06Rik; A130023A14; AA474864; activating molecule in beclin-1-regulated autophagy; activating molecule in Beclin1-regulated autophagy; activating molecule in BECN1-regulated autophagy protein 1; AMBRA1; autophagy and beclin 1 regulator 1; autophagy/beclin 1 regulator 1; autophagy/beclin-1 regulator 1; AV021921; D030051N19Rik; DCAF3; DDB1 and CUL4 associated factor 3; hypothetical protein; hypothetical protein LOC517263; ischemia related factor NYW-1; Kiaa1736; mKIAA1736; Nyw1; WD repeat domain 94; WDR94

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228361, 55626, 59319

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
A2AH22, Q9C0C7

Gene Symbols:
AMBRA1

Immunogen:
A synthesized peptide derived from human AMBRA1(Accession Q9C0C7), corresponding to amino acid residues E1046-A1096.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102349

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Antigen:
PP1 beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ppp1cb

Gene Alias:
1200010B19; epididymis secretory sperm binding protein Li 80p; HEL-S-80p; hypothetical protein LOC538829; MGC21657; PP1B; PP-1B; PP1beta; PP1-BETA; PP2CB; PP2CBETA; PP2C-beta-X; PPC2BETAX; PPP1CB; PPP1CD; protein phosphatase 1; protein phosphatase 1 catalytic subunit beta; protein phosphatase 1, catalytic subunit, beta isoform; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase 1, catalytic subunit, delta isoform; protein phosphatase 1-beta; protein phosphatase 1-delta; protein phosphatase-1a; serine/threonine protein phosphatase PP1-beta catalytic subunit; serine/threonine-protein phosphatase PP1-beta catalytic subunit

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19046, 25594, 5500

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P62140, P62141, P62142

Gene Symbols:
Ppp1cb

Immunogen:
A synthesized peptide derived from human PPP1CB(Accession P62140), corresponding to amino acid residues S298-R327.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5102351

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Antigen:
MAGED1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAGED1

Gene Alias:
11B6; 2810433C11Rik; 5430405L04Rik; BCG-1; Dlixin; Dlxin1; DLXIN-1; DXBwg1492e; JCL-1; MAGE family member D1; MAGE tumor antigen CCF; MAGED1; MAGE-D1; MAGE-D1 antigen; Maged2; melanoma antigen family D, 1; melanoma antigen family D1; melanoma antigen, family D, 1; melanoma-associated antigen D1; mFLJ00163; neurotrophin receptor-interacting MAGE homolog; NRAGE; PP2250; PRO2292; Sertoli cell necdin-related gene protein 1; SNERG-1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84469, 94275, 9500

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9ES73, Q9QYH6, Q9Y5V3

Gene Symbols:
MAGED1

Immunogen:
A synthesized peptide derived from human MAGED1(Accession Q9Y5V3), corresponding to amino acid residues D409-N459.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102352

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Antigen:
TYMP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TYMP

Gene Alias:
2900072D10Rik; ECGF; Ecgf1; endothelial cell growth factor 1 (platelet-derived); gliostatin; hPD-ECGF; MEDPS1; MNGIE; MTDPS1; OTTHUMP00000196767; OTTHUMP00000196770; PD TP; PDECGF; PD-ECGF; Pdgfec; platelet derived growth factor, endothelial cell; Platelet-derived endothelial cell growth factor; TdRPase; thymidine phosphorylase; TP; TYMP

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1890, 315219, 72962

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P19971, Q5FVR2, Q99N42

Gene Symbols:
TYMP

Immunogen:
A synthesized peptide derived from human TYMP(Accession P19971), corresponding to amino acid residues M1-G46.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG