PIPA520511

AMBRA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520511-Each-of-1 In Stock ₹ 44,790.66

PIPA520511 - Each of 1

₹ 44,790.66

In Stock

Quantity

1

Base Price: ₹ 44,790.66

GST (18%): ₹ 8,062.319

Total Price: ₹ 52,852.979

Antigen

AMBRA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AMBRA1

Gene Alias

2310079H06Rik; A130023A14; AA474864; activating molecule in beclin-1-regulated autophagy; activating molecule in Beclin1-regulated autophagy; activating molecule in BECN1-regulated autophagy protein 1; AMBRA1; autophagy and beclin 1 regulator 1; autophagy/beclin 1 regulator 1; autophagy/beclin-1 regulator 1; AV021921; D030051N19Rik; DCAF3; DDB1 and CUL4 associated factor 3; hypothetical protein; hypothetical protein LOC517263; ischemia related factor NYW-1; Kiaa1736; mKIAA1736; Nyw1; WD repeat domain 94; WDR94

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

228361, 55626, 59319

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

A2AH22, Q9C0C7

Gene Symbols

AMBRA1

Immunogen

A 15 amino acid peptide from near the carboxy terminus of human Ambra1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is NIH-3T3 cell lysate
  • PA5-20511 can be used with blocking peptide PEP-0631
  • Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
  • It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
  • Beclin-1, a principal regulator of autophagosome formation, is in turn regulated by Ambra1
  • Ambra1 associates with Beclin-1 through a region near its center as determined by yeast two-hybrid assay
  • Null mutations in this gene in mice resulted in embryonic lethality with severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic death
  • Furthermore, down-regulation of Ambra1 in cultured cells though RNA interference decreased the level of rapamycin- and nutrient starvation-induced autophagy
  • Multiple isoforms of Ambra1 are known to exist.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA520511

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Antigen:
AMBRA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AMBRA1

Gene Alias:
2310079H06Rik; A130023A14; AA474864; activating molecule in beclin-1-regulated autophagy; activating molecule in Beclin1-regulated autophagy; activating molecule in BECN1-regulated autophagy protein 1; AMBRA1; autophagy and beclin 1 regulator 1; autophagy/beclin 1 regulator 1; autophagy/beclin-1 regulator 1; AV021921; D030051N19Rik; DCAF3; DDB1 and CUL4 associated factor 3; hypothetical protein; hypothetical protein LOC517263; ischemia related factor NYW-1; Kiaa1736; mKIAA1736; Nyw1; WD repeat domain 94; WDR94

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228361, 55626, 59319

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
A2AH22, Q9C0C7

Gene Symbols:
AMBRA1

Immunogen:
A 15 amino acid peptide from near the carboxy terminus of human Ambra1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520512

--


Antigen:
AMBRA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AMBRA1

Gene Alias:
2310079H06Rik; A130023A14; AA474864; activating molecule in beclin-1-regulated autophagy; activating molecule in Beclin1-regulated autophagy; activating molecule in BECN1-regulated autophagy protein 1; AMBRA1; autophagy and beclin 1 regulator 1; autophagy/beclin 1 regulator 1; autophagy/beclin-1 regulator 1; AV021921; D030051N19Rik; DCAF3; DDB1 and CUL4 associated factor 3; hypothetical protein; hypothetical protein LOC517263; ischemia related factor NYW-1; Kiaa1736; mKIAA1736; Nyw1; WD repeat domain 94; WDR94

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
228361, 55626, 59319

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
A2AH22, Q9C0C7

Gene Symbols:
AMBRA1

Immunogen:
An 18 amino acid peptide from near the amino terminus of human Ambra1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520514

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Antigen:
LGI4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LGI4

Gene Alias:
clp; leucine rich repeat LGI family member 4; leucine-rich glioma inactivated protein 4; leucine-rich glioma-inactivated gene 4; leucine-rich glioma-inactivated protein 4; Leucine-rich repeat LGI family member 4; leucine-rich repeat LGI family, member 4; LGI1-like protein 3; LGI4; Lgil3; UNQ6515/PRO21485

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
163175, 243914, 361549

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8K1S1, Q8N135

Gene Symbols:
LGI4

Immunogen:
A 17 amino acid peptide from near the carboxy terminus of human LGI4.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA520515

--


Antigen:
LGI4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LGI4

Gene Alias:
clp; leucine rich repeat LGI family member 4; leucine-rich glioma inactivated protein 4; leucine-rich glioma-inactivated gene 4; leucine-rich glioma-inactivated protein 4; Leucine-rich repeat LGI family member 4; leucine-rich repeat LGI family, member 4; LGI1-like protein 3; LGI4; Lgil3; UNQ6515/PRO21485

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
163175, 243914, 361549

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q8K1S1, Q8N135

Gene Symbols:
LGI4

Immunogen:
A 14 amino acid peptide from near the center of human LGI4.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG