PIPA5102584

TRAIL Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102584-Each-of-1 In Stock ₹ 43,592.82

PIPA5102584 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

TRAIL

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNFSF10

Gene Alias

A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8743

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P50591

Gene Symbols

TNFSF10

Immunogen

A synthesized peptide derived from human TNFSF10(Accession P50591), corresponding to amino acid residues K43-L93.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total TNFSF10
  • TRAIL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family
  • TRAIL preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues
  • TRAIL binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG
  • The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis
  • The binding of TRAIL protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3
  • Receptors for TRAIL include two death domain containing receptors, death receptor 4 (DR4) and DR5, as well as two decoy receptors, DcR1 and DcR2, lacking the intracellular signaling death domain
  • TRAIL is a type II membrane protein and expressed in a variety of human tissues
  • Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5102584

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Antigen:
TRAIL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFSF10

Gene Alias:
A330042I21Rik; AI448571; Apo-2 ligand; APO2L; Apo-2L; CD253; CD253 antigen; chemokine tumor necrosis factor ligand superfamily member 10; Ly81; Protein TRAIL; TL2; TN; TNF superfamily member 10; TNF-related apoptosis inducing ligand; TNF-related apoptosis inducing ligand TRAIL; TNF-related apoptosis-inducing ligand; Tnfsf10; TNLG6A; TRAIL; TRAIL protein; TRAIL/APO2L; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor (ligand) superfamily member 10; tumor necrosis factor (ligand) superfamily, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor ligand 6A; tumor necrosis factor ligand superfamily member 10; tumor necrosis factor superfamily member 10

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8743

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P50591

Gene Symbols:
TNFSF10

Immunogen:
A synthesized peptide derived from human TNFSF10(Accession P50591), corresponding to amino acid residues K43-L93.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102585

--


Antigen:
NUMBL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Numbl

Gene Alias:
CAG3A; CTG3a; NBL; numb homolog (Drosophila)-like; numb homolog-like; NUMB like, endocytic adaptor protein; Numbl; NUMBLIKE; numb-like; numb-like protein; NUMBR; Numb-R; numb-related protein; TNRC23

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18223, 292732, 9253

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
A1L1I3, O08919, Q9Y6R0

Gene Symbols:
Numbl

Immunogen:
A synthesized peptide derived from human NUMBL(Accession Q9Y6R0), corresponding to amino acid residues L533-A583.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102586

--


Antigen:
GAS2L1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GAS2L1

Gene Alias:
4930500E24Rik; D0Jmb1; Gar22; GAS2L1; GAS2-like protein 1; GAS2-related protein; GAS2-related protein on chromosome 22; growth arrest specific 2 like 1; growth arrest-specific 2 like 1; growth arrest-specific protein 2-like 1; TU-71.1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10634, 360973, 78926

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8JZP9, Q99501

Gene Symbols:
GAS2L1

Immunogen:
A synthesized peptide derived from human GAS2L1(Accession Q99501), corresponding to amino acid residues C624-R674.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102587

--


Antigen:
MALT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MALT1

Gene Alias:
A630046N12; caspase-like protein; D430033E09Rik; DKFZp434L132; IMD12; MALT lymphoma-associated translocation; Malt1; malt-1; MALT1 paracaspase; MALT1 protease; MLT; MLT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; paracaspase; paracaspase 1; paracaspase-1; PCASP1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10892, 240354, 307366

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q2TBA3, Q9UDY8

Gene Symbols:
MALT1

Immunogen:
A synthesized peptide derived from human MALT1(Accession Q9UDY8), corresponding to amino acid residues C317-Y367.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG