PIPA5102849

Phospho-IRAK4 (Thr345, Ser346) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102849-Each-of-1 In Stock ₹ 43,336.14

PIPA5102849 - Each of 1

₹ 43,336.14

In Stock

Quantity

1

Base Price: ₹ 43,336.14

GST (18%): ₹ 7,800.505

Total Price: ₹ 51,136.645

Antigen

Phospho-IRAK4 (Thr345, Ser346)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRAK4

Gene Alias

8430405M07Rik; 9330209D03Rik; interleukin 1 receptor associated kinase 4; interleukin-1; interleukin-1 receptor-associated kinase 4; IPD1; Irak4; IRAK-4; NY-REN-64; REN64; renal carcinoma antigen NY-REN-64

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

266632, 300177, 51135

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8R4K2, Q9NWZ3

Gene Symbols

IRAK4

Immunogen

A synthesized peptide derived from human IRAK4(Accession Q9NWZ3), corresponding to amino acid residues around phosphorylated Ser346.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5102441

--

Img

Thermo Scientific

PIPA5103300

--

Img

Thermo Scientific

PIPA5102306

--

Img

Thermo Scientific

PIPA5103269

--

Img

Thermo Scientific

PIPA5102871

--

Img

Thermo Scientific

PIPA5103668

--

Img

Thermo Scientific

PIPA5103438

--

Img

Thermo Scientific

PIPA5103212

--

Description

  • Antibody detects endogenous levels of IRAK4 only when phosphorylated at Thr345/Ser346
  • IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways
  • Overexpression of IRAK-4 activates NF-kappa-B and MAPK pathways
  • IRAK-4 interacts with and phosphorylates IRAK-1
  • IRAK-4-deficient animals are completely resistant to the challenge with LPS
  • Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges
  • Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses and in innate immunity.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5102849

--


Antigen:
Phospho-IRAK4 (Thr345, Ser346)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRAK4

Gene Alias:
8430405M07Rik; 9330209D03Rik; interleukin 1 receptor associated kinase 4; interleukin-1; interleukin-1 receptor-associated kinase 4; IPD1; Irak4; IRAK-4; NY-REN-64; REN64; renal carcinoma antigen NY-REN-64

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
266632, 300177, 51135

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8R4K2, Q9NWZ3

Gene Symbols:
IRAK4

Immunogen:
A synthesized peptide derived from human IRAK4(Accession Q9NWZ3), corresponding to amino acid residues around phosphorylated Ser346.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102851

--


Antigen:
LEF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LEF1

Gene Alias:
3000002B05; AI451430; DKFZp586H0919; FLJ46390; HGNC:6551; HMG Binding Domain; LEF1; Lef-1; lymphoid enhancer binding factor 1; lymphoid enhancer binding factor 1 short isoform; lymphoid enhancer-binding factor 1; OTTHUMP00000219736; OTTHUMP00000219737; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
161452, 16842, 51176

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P27782, Q9QXN1, Q9UJU2

Gene Symbols:
LEF1

Immunogen:
A synthesized peptide derived from human LEF1(Accession Q9UJU2), corresponding to amino acid residues T265-A315.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102853

--


Antigen:
Phospho-PERK (Thr982)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF2AK3

Gene Alias:
2.7.11.1; AI427929; EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3; eukaryotic translation initiation factor 2-alpha kinase 3; HsPEK; OTTHUMP00000207187; OTTHUMP00000207188; Pancreatic eIF2-alpha kinase; PEK; Perk; PRKR-like endoplasmic reticulum kinase; WRS

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13666, 29702, 9451

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NZJ5, Q9Z1Z1, Q9Z2B5

Gene Symbols:
EIF2AK3

Immunogen:
A synthesized peptide derived from human EIF2AK3(Accession Q9NZJ5), corresponding to amino acid residues around phosphorylated Thr 982.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102854

--


Antigen:
Phospho-Doublecortin (Ser335)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCX

Gene Alias:
DBCN; Dbct; DC; Dcn; DCX; doublecortex; doublecortin; doublin; lissencephalin-X; lissencephaly, X-linked (doublecortin); LISX; Lis-X; LIS-XD; Neuronal migration protein doublecortin; OTTHUMP00000023860; OTTHUMP00000216316; SCLH; XLIS

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13193, 1641, 84394

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43602, O88809, Q9ESI7

Gene Symbols:
DCX

Immunogen:
A synthesized peptide derived from human DCX(Accession O43602), corresponding to amino acid residues around phosphorylated Ser335.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG