PIPA5103585

Agrin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5103585-Each-of-1 In Stock ₹ 45,218.46

PIPA5103585 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

Agrin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Agrn

Gene Alias

AGR; Agrin; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 22 kDa fragment; Agrin C-terminal 90 kDa fragment; Agrin N-terminal 110 kDa subunit; agrin proteoglycan; Agrn; C22; C90; CMS8; CMSPPD; nmf380; RP23-139J18.2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11603, 25592, 375790

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

A2ASQ1, O00468, P25304

Gene Symbols

Agrn

Immunogen

A synthesized peptide derived from human AGRN(Accession O00468), corresponding to amino acid residues V1978-P2028.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total AGRN
  • Agrin is a molecule that resides in the basal lamina of muscle cells and directs key events in post synaptic differentiation
  • Most notably, Agrin is responsible for the clustering of acetylcholine receptors (AChRs) on the cell surface and their localization to the neuromuscular junction
  • Several Agrin variants have been identified which arise from alternative mRNA splicings
  • Agrin splice forms having inserts at two sites in the carboxy terminus designated &quotey&quote and &quotez&quote display a high affinity for AChRs, while splice forms lacking these inserts associate with AChRs weakly
  • Muscle alpha-dystroglycan has been postulated to be the receptor for the clustering activity of agrin; however, this is a point of contention
  • Tyrosine phosphorylation has been implicated as a required early step in AChR aggregation
  • Interestingly, a unique receptor tyrosine kinase, designated MuSK, has been discovered that interacts with Agrin and is specifically localized to developing muscle.

Compare Similar Items

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Img

Thermo Scientific

PIPA5103585

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Antigen:
Agrin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Agrn

Gene Alias:
AGR; Agrin; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 22 kDa fragment; Agrin C-terminal 90 kDa fragment; Agrin N-terminal 110 kDa subunit; agrin proteoglycan; Agrn; C22; C90; CMS8; CMSPPD; nmf380; RP23-139J18.2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11603, 25592, 375790

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
A2ASQ1, O00468, P25304

Gene Symbols:
Agrn

Immunogen:
A synthesized peptide derived from human AGRN(Accession O00468), corresponding to amino acid residues V1978-P2028.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103587

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Antigen:
AGXT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Agxt2

Gene Alias:
(R)-3-amino-2-methylpropionate--pyruvate transaminase; AGT 2; Agt2; Agxt2; AI303810; AI663818; alanine-glyoxylate aminotransferase 2; alanine--glyoxylate aminotransferase 2; alanine--glyoxylate aminotransferase 2, mitochondrial; beta-ALAAT II; Beta-alanine-pyruvate aminotransferase; DAIBAT; D-AIBAT

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
268782, 64902, 83784

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q3UEG6, Q64565, Q9BYV1

Gene Symbols:
Agxt2

Immunogen:
A synthesized peptide derived from human AGXT2(Accession Q9BYV1), corresponding to amino acid residues L176-T226.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103589

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Antigen:
ALDH3B2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aldh3b2

Gene Alias:
acetaldehyde dehydrogenase 8; AI848594; aldehyde dehydrogenase 3 family member B2; aldehyde dehydrogenase 3 family, member B2; aldehyde dehydrogenase 8; Aldehyde dehydrogenase family 3 member B2; Aldh3b2; ALDH8; C130048D07Rik

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
222

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P48448

Gene Symbols:
Aldh3b2

Immunogen:
A synthesized peptide derived from human ALDH3B2(Accession P48448), corresponding to amino acid residues F338-L385.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103590

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Antigen:
AKR1C4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKR1C4

Gene Alias:
3-alpha-HSD; 3-alpha-HSD1; 3-alpha-hydroxysteroid dehydrogenase type I; AKR1C4; Aldo-keto reductase family 1 member C4; aldo-keto reductase family 1, member C4; C11; CDR; CHDR; Chlordecone reductase; chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4; DD4; DD-4; Dihydrodiol dehydrogenase 4; dihydrodiol dehydrogenase isozyme DD4; HAKRA; HGNC:387; MGC22581; type I 3-alpha-hydroxysteroid dehydrogenase

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1109

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P17516

Gene Symbols:
AKR1C4

Immunogen:
A synthesized peptide derived from human AKR1C4(Accession P17516), corresponding to amino acid residues M1-N32.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG