PIPA5103956

NPHP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5103956-Each-of-1 In Stock ₹ 44,705.10

PIPA5103956 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NPHP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NPHP1

Gene Alias

JBTS4; juvenile nephronophthisis 1 protein; nephrocystin 1; Nephrocystin1; nephrocystin-1; nephronophthisis 1 (juvenile); nephronophthisis 1 (juvenile) homolog; nephronophthisis 1 (juvenile) homolog (human); NPH1; NPHP1; SLSN1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4867, 53885

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O15259, Q9QY53

Gene Symbols

NPHP1

Immunogen

A synthesized peptide derived from human NPHP1(Accession O15259), corresponding to amino acid residues C454-P504.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total NPHP1
  • Juvenile nephronophthisis type 1 is caused by mutations of NPHP1, the gene encoding for nephrocystin
  • Nephrocystin interacts with p130Cas (BCAR1), proline-rich tyrosine kinase-2 (PTK2B or Pyk2), and tensin in embryonic kidney and testis, indicating that these proteins participate in a common signaling pathway
  • Nephrocystin and p130Cas interact in mammalian cells and both proteins prominently localize at or near sites of cell-cell contact in polarized Madin-Darby canine kidney epithelial cells
  • Expression of nephrocystin results in phosphorylation of Pyk2 on Tyrosine 402 as well as activation of downstream mitogen-activated protein kinases, such as ERK1 and ERK2
  • Nephrocystin contains a src-homology 3 (SH3) domain, which is highly conserved throughout evolution.

Compare Similar Items

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Img

Thermo Scientific

PIPA5103956

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Antigen:
NPHP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPHP1

Gene Alias:
JBTS4; juvenile nephronophthisis 1 protein; nephrocystin 1; Nephrocystin1; nephrocystin-1; nephronophthisis 1 (juvenile); nephronophthisis 1 (juvenile) homolog; nephronophthisis 1 (juvenile) homolog (human); NPH1; NPHP1; SLSN1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4867, 53885

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O15259, Q9QY53

Gene Symbols:
NPHP1

Immunogen:
A synthesized peptide derived from human NPHP1(Accession O15259), corresponding to amino acid residues C454-P504.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103957

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Antigen:
UNC5A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Unc5a

Gene Alias:
Kiaa1976; mKIAA1976; netrin receptor UNC5A; netrin receptor Unc5h1; protein unc-5 homolog 1; Protein unc-5 homolog A; transmembrane receptor Unc5H1; unc5 (C.elegans homolog) a; unc5 homolog 1; unc-5 homolog 1; unc-5 homolog A; unc-5 homolog A (C. elegans); unc-5 netrin receptor A; UNC5A; Unc5h1; UNC5H1FLJ16449

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107448, 60629, 90249

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O08721, Q6ZN44, Q8K1S4

Gene Symbols:
Unc5a

Immunogen:
A synthesized peptide derived from human UNC5A(Accession Q6ZN44), corresponding to amino acid residues S356-G406.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103958

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Antigen:
NGRN

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NGRN

Gene Alias:
AW552001; DSC92; FI58G; FI58Gm; HT020; mesenchymal stem cell protein DSC92; m-Neugrin; Neugrin; neugrin, neurite outgrowth associated; neurite outgrowth associated protein; neurite outgrowth-associated protein; NGRN; Spinal cord-derived protein FI58G

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51335

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NPE2

Gene Symbols:
NGRN

Immunogen:
A synthesized peptide derived from human NGRN(Accession Q9NPE2), corresponding to amino acid residues V17-Q67.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5103959

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Antigen:
Neurensin 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NRSN2

Gene Alias:
C20orf98; dJ1103G7.6; FLJ23329; Gm123; neurensin 2; Neurensin2; Neurensin-2; NRSN2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80023

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9GZP1

Gene Symbols:
NRSN2

Immunogen:
A synthesized peptide derived from human NRSN2(Accession Q9GZP1), corresponding to amino acid residues E167-S204.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG