PIPA5104602

Phospho-eIF3b (Ser154) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5104602-Each-of-1 In Stock ₹ 44,705.10

PIPA5104602 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-eIF3b (Ser154)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EIF3B

Gene Alias

AL033316; AL033334; AL033369; AW208965; D5Wsu45e; eIF3 p110; eIF3 p116; EIF3B; eIF3b {ECO:0000255; eIF-3-eta; EIF3-ETA; eIF-3-eta {ECO:0000255; EIF3-P110; EIF3-P116; EIF3S9; eukaryotic translation initiation factor 3 subunit 9; eukaryotic translation initiation factor 3 subunit 9 {ECO:0000255; Eukaryotic translation initiation factor 3 subunit B; eukaryotic translation initiation factor 3 subunit B {ECO:0000255; eukaryotic translation initiation factor 3, subunit 9 (eta); eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD); eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa; eukaryotic translation initiation factor 3, subunit B; HAMAP-Rule:MF_03001}; hPrt1; MGC104664; MGC131875; PRT1; Prt1 homolog

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

27979, 288516, 8662

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P55884, Q4G061, Q8JZQ9

Gene Symbols

EIF3B

Immunogen

A synthesized peptide derived from human EIF3B(Accession P55884), corresponding to amino acid residues around phosphorylated Ser154.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of EIF3B only when phosphorylated at Ser154
  • RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815)
  • The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC)
  • The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition
  • The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:9388245, PubMed:17581632)
  • The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773)
  • [UniProt]

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Img

Thermo Scientific

PIPA5104602

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Antigen:
Phospho-eIF3b (Ser154)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF3B

Gene Alias:
AL033316; AL033334; AL033369; AW208965; D5Wsu45e; eIF3 p110; eIF3 p116; EIF3B; eIF3b {ECO:0000255; eIF-3-eta; EIF3-ETA; eIF-3-eta {ECO:0000255; EIF3-P110; EIF3-P116; EIF3S9; eukaryotic translation initiation factor 3 subunit 9; eukaryotic translation initiation factor 3 subunit 9 {ECO:0000255; Eukaryotic translation initiation factor 3 subunit B; eukaryotic translation initiation factor 3 subunit B {ECO:0000255; eukaryotic translation initiation factor 3, subunit 9 (eta); eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD); eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa; eukaryotic translation initiation factor 3, subunit B; HAMAP-Rule:MF_03001}; hPrt1; MGC104664; MGC131875; PRT1; Prt1 homolog

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27979, 288516, 8662

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P55884, Q4G061, Q8JZQ9

Gene Symbols:
EIF3B

Immunogen:
A synthesized peptide derived from human EIF3B(Accession P55884), corresponding to amino acid residues around phosphorylated Ser154.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104604

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Antigen:
Phospho-Cytokeratin 17 (Ser44)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KRT17

Gene Alias:
39.1; CK17; CK-17; cytokeratin-17; hard keratin; K17; Ka17; keratin 17; keratin 17, type I; keratin complex 1, acidic, gene 17; keratin, type I cytoskeletal 17; Keratin-17; Krt1-17; Krt17; krt17 {ECO:0000250; PC; PC2; PCHC1; Type I keratin Ka17; UniProtKB:Q04695}

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16667, 287702, 3872

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q04695, Q6IFU8, Q9QWL7

Gene Symbols:
KRT17

Immunogen:
A synthesized peptide derived from human KRT17(Accession Q04695), corresponding to amino acid residues around phosphorylated Ser44.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104606

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Antigen:
Phospho-KIF1B (Ser1487)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KIF1B

Gene Alias:
A530096N05Rik; AI448212; AI506502; CMT2; CMT2A; CMT2A1; D4Mil1e; HMSNII; KIAA0591; KIAA1448; Kif1b; KIF1Bp130; KIF1Bp204; kinesin family member 1B; kinesin heavy chain member 1B; kinesin superfamily protein KIF1B; kinesin-family protein KIF1Bbeta3; kinesin-like protein KIF1B; Klp; N-3 kinesin; NBLST1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117548, 16561, 23095

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60333, O88658, Q60575

Gene Symbols:
KIF1B

Immunogen:
A synthesized peptide derived from human KIF1B(Accession O60333), corresponding to amino acid residues around phosphorylated Ser1487.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5104607

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Antigen:
Phospho-KSR1 (Ser392)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KSR1

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16706, 8844

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q61097, Q8IVT5

Gene Symbols:
KSR1

Immunogen:
A synthesized peptide derived from mouse KSR1(Accession Q61097), corresponding to amino acid residues around phosphorylated Ser392.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG