PIPA5104888
Phospho-BRCA1 (Ser1524) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5104888-Each-of-1 | In Stock | ₹ 43,592.82 |
PIPA5104888 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,592.82
GST (18%): ₹ 7,846.708
Total Price: ₹ 51,439.528
Antigen
Phospho-BRCA1 (Ser1524)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BRCA1
Gene Alias
brca 1; Brca1; brca-1; BRCA1, DNA repair associated; BRCA1/BRCA2-containing complex, subunit 1; BRCAI; BRCC1; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein 1; breast cancer 1; breast cancer 1 early onset; breast cancer 1, early onset; breast cancer associated 1; breast cancer type 1 susceptibility protein; Breast cancer type 1 susceptibility protein homolog; BROVCA1; BROVCA12; Delta772-3095; early onset breast cancer 1; Fanconi anemia, complementation group S; FANCS; IRIS; OTTHUMP00000212147; OTTHUMP00000212148; OTTHUMP00000212149; OTTHUMP00000212150; OTTHUMP00000212151; OTTHUMP00000212155; PNCA4; PPP1R53; protein phosphatase 1, regulatory subunit 53; PSCP; RING finger protein 53; RING-type E3 ubiquitin transferase BRCA1; RNF53; truncated BRCA1; truncated breast and ovarian cancer susceptibility protein 1; truncated breast and ovarian cancer sususceptibility protein 1; truncated breast cancer type 1 susceptibility protein
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12189, 497672, 672
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
O54952, P38398, P48754
Gene Symbols
BRCA1
Immunogen
A synthesized peptide derived from human BRCA1(Accession P38398), corresponding to amino acid residues around phosphorylated Ser1524.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of BRCA1 only when phosphorylated at Serine 1524
- BRCA1 (breast and ovarian cancer susceptibility protein 1) is a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor in combination with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC (for BRCA1 associated genome surveillance complex)
- BRCA1 associates with RNA polymerase II, and through the C terminal domain, also interacts with histone deacetylase complex
- The BRCA1 protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
- Mutations in the BRCA1 gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
- Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
- Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
- A related pseudogene, which is also located on chromosome 17, has been identified.
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Antigen: Phospho-BRCA1 (Ser1524)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BRCA1
Gene Alias: brca 1; Brca1; brca-1; BRCA1, DNA repair associated; BRCA1/BRCA2-containing complex, subunit 1; BRCAI; BRCC1; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein 1; breast cancer 1; breast cancer 1 early onset; breast cancer 1, early onset; breast cancer associated 1; breast cancer type 1 susceptibility protein; Breast cancer type 1 susceptibility protein homolog; BROVCA1; BROVCA12; Delta772-3095; early onset breast cancer 1; Fanconi anemia, complementation group S; FANCS; IRIS; OTTHUMP00000212147; OTTHUMP00000212148; OTTHUMP00000212149; OTTHUMP00000212150; OTTHUMP00000212151; OTTHUMP00000212155; PNCA4; PPP1R53; protein phosphatase 1, regulatory subunit 53; PSCP; RING finger protein 53; RING-type E3 ubiquitin transferase BRCA1; RNF53; truncated BRCA1; truncated breast and ovarian cancer susceptibility protein 1; truncated breast and ovarian cancer sususceptibility protein 1; truncated breast cancer type 1 susceptibility protein
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12189, 497672, 672
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O54952, P38398, P48754
Gene Symbols: BRCA1
Immunogen: A synthesized peptide derived from human BRCA1(Accession P38398), corresponding to amino acid residues around phosphorylated Ser1524.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-BRCA1 (Ser1524)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BRCA1
Gene Alias:
brca 1; Brca1; brca-1; BRCA1, DNA repair associated; BRCA1/BRCA2-containing complex, subunit 1; BRCAI; BRCC1; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein 1; breast cancer 1; breast cancer 1 early onset; breast cancer 1, early onset; breast cancer associated 1; breast cancer type 1 susceptibility protein; Breast cancer type 1 susceptibility protein homolog; BROVCA1; BROVCA12; Delta772-3095; early onset breast cancer 1; Fanconi anemia, complementation group S; FANCS; IRIS; OTTHUMP00000212147; OTTHUMP00000212148; OTTHUMP00000212149; OTTHUMP00000212150; OTTHUMP00000212151; OTTHUMP00000212155; PNCA4; PPP1R53; protein phosphatase 1, regulatory subunit 53; PSCP; RING finger protein 53; RING-type E3 ubiquitin transferase BRCA1; RNF53; truncated BRCA1; truncated breast and ovarian cancer susceptibility protein 1; truncated breast and ovarian cancer sususceptibility protein 1; truncated breast cancer type 1 susceptibility protein
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12189, 497672, 672
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O54952, P38398, P48754
Gene Symbols:
BRCA1
Immunogen:
A synthesized peptide derived from human BRCA1(Accession P38398), corresponding to amino acid residues around phosphorylated Ser1524.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Calcium Sensing Receptor (Thr888)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CASR
Gene Alias: BoPCaR1; Ca sensing receptor; Ca(2+)-sensing receptor; calcium sensing receptor; calcium-sensing receptor; Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); CaR; CaSR; CaSR antibody; cation sensing receptor; EIG8; Extracellular calcium-sensing receptor; FHH; FIH; G protein coupled receptor, family C, group 2, member A; G protein-coupled receptor, family C, group 2, member A; Gprc2a; HHC; HHC1; HYPOC1; LOW QUALITY PROTEIN: extracellular calcium-sensing receptor; NSHPT; parathyroid Ca(2+)-sensing receptor 1; parathyroid cell calcium-sensing receptor; Parathyroid cell calcium-sensing receptor 1; PCaR1
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12374, 24247, 846
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P41180, P48442, Q9QY96
Gene Symbols: CASR
Immunogen: A synthesized peptide derived from human CASR(Accession P41180), corresponding to amino acid residues around phosphorylated Thr888.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Calcium Sensing Receptor (Thr888)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CASR
Gene Alias:
BoPCaR1; Ca sensing receptor; Ca(2+)-sensing receptor; calcium sensing receptor; calcium-sensing receptor; Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); CaR; CaSR; CaSR antibody; cation sensing receptor; EIG8; Extracellular calcium-sensing receptor; FHH; FIH; G protein coupled receptor, family C, group 2, member A; G protein-coupled receptor, family C, group 2, member A; Gprc2a; HHC; HHC1; HYPOC1; LOW QUALITY PROTEIN: extracellular calcium-sensing receptor; NSHPT; parathyroid Ca(2+)-sensing receptor 1; parathyroid cell calcium-sensing receptor; Parathyroid cell calcium-sensing receptor 1; PCaR1
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12374, 24247, 846
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P41180, P48442, Q9QY96
Gene Symbols:
CASR
Immunogen:
A synthesized peptide derived from human CASR(Accession P41180), corresponding to amino acid residues around phosphorylated Thr888.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-HNF4A (Ser313)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HNF4A
Gene Alias: alpha transcription factor 4; FLJ39654; FRTS4; hepatic nuclear factor 4 alpha; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; hepatocyte nuclear factor 4-alpha; HNF4; Hnf-4; HNF4 alpha; Hnf4a; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; HNF-4-alpha; HNF4-alpha; HNF4alpha10; HNF4alpha10/11/12; HNF4alpha11; HNF4alpha12; MODY; MODY1; NR2A1; NR2A21; Nuclear receptor 2A1; nuclear receptor subfamily 2 group A member 1; TCF; TCF14; TCF-14; Transcription factor 14; transcription factor HNF-4
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15378, 25735, 3172
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P22449, P41235, P49698
Gene Symbols: HNF4A
Immunogen: A synthesized peptide derived from human HNF4A(Accession P41235), corresponding to amino acid residues around phosphorylated Ser313.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-HNF4A (Ser313)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HNF4A
Gene Alias:
alpha transcription factor 4; FLJ39654; FRTS4; hepatic nuclear factor 4 alpha; hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4 alpha; hepatocyte nuclear factor 4, alpha; hepatocyte nuclear factor 4-alpha; HNF4; Hnf-4; HNF4 alpha; Hnf4a; HNF4a7; HNF4a8; HNF4a9; Hnf4alpha; HNF-4-alpha; HNF4-alpha; HNF4alpha10; HNF4alpha10/11/12; HNF4alpha11; HNF4alpha12; MODY; MODY1; NR2A1; NR2A21; Nuclear receptor 2A1; nuclear receptor subfamily 2 group A member 1; TCF; TCF14; TCF-14; Transcription factor 14; transcription factor HNF-4
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15378, 25735, 3172
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P22449, P41235, P49698
Gene Symbols:
HNF4A
Immunogen:
A synthesized peptide derived from human HNF4A(Accession P41235), corresponding to amino acid residues around phosphorylated Ser313.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-TPL2 (Thr290)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP3K8
Gene Alias: augmented in rheumatoid arthritis 2; AURA2; Cancer Osaka thyroid oncogene; cancer Osaka thyroid, oncogene; CCOT; c-COT; COT; cot (cancer Osaka thyroid) oncogene; COT proto-oncogene serine/threonine-protein kinase; Cot/Tpl2; D17TPL2; EC 1.14.16.2; Est; Estf; Ewing sarcoma transformant; FLJ10486; M3K8; MAP3K 8; Map3k8; MEKK8; mitogen activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Protein kinase cot; Proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; serine/threonine kinase (Tpl-2); serine/threonine-protein kinase cot; TH isoform 3; TH isoform a; TH-4; TPL 2; Tpl2; TPL-2; Tumor progression locus 2; TY3H; TYH
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116596, 1326, 26410
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P41279, Q07174, Q63562
Gene Symbols: MAP3K8
Immunogen: A synthesized peptide derived from human MAP3K8(Accession P41279), corresponding to amino acid residues around phosphorylated Thr290.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TPL2 (Thr290)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP3K8
Gene Alias:
augmented in rheumatoid arthritis 2; AURA2; Cancer Osaka thyroid oncogene; cancer Osaka thyroid, oncogene; CCOT; c-COT; COT; cot (cancer Osaka thyroid) oncogene; COT proto-oncogene serine/threonine-protein kinase; Cot/Tpl2; D17TPL2; EC 1.14.16.2; Est; Estf; Ewing sarcoma transformant; FLJ10486; M3K8; MAP3K 8; Map3k8; MEKK8; mitogen activated protein kinase kinase kinase 8; mitogen-activated protein kinase kinase kinase 8; Protein kinase cot; Proto-oncogene c-Cot; proto-oncogene serine/threoine protein kinase; serine/threonine kinase (Tpl-2); serine/threonine-protein kinase cot; TH isoform 3; TH isoform a; TH-4; TPL 2; Tpl2; TPL-2; Tumor progression locus 2; TY3H; TYH
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116596, 1326, 26410
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P41279, Q07174, Q63562
Gene Symbols:
MAP3K8
Immunogen:
A synthesized peptide derived from human MAP3K8(Accession P41279), corresponding to amino acid residues around phosphorylated Thr290.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG