PIPA5105039

Phospho-ALK (Tyr1507) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105039-Each-of-1 In Stock ₹ 44,191.74

PIPA5105039 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

Phospho-ALK (Tyr1507)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ALK

Gene Alias

Alk; ALK tyrosine kinase receptor; ALK/NPM1 fusion gene; anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki1; Anaplastic Lymphoma Kinase p80; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; npm-alk; p80; Tcrz; TFG/ALK

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11682, 238

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P97793, Q9UM73

Gene Symbols

ALK

Immunogen

A synthesized peptide derived from human ALK(Accession Q9UM73), corresponding to amino acid residues around phosphorylated Tyr1507.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5105238

--

Img

Thermo Scientific

PIPA5104903

--

Img

Thermo Scientific

PIPA5104904

--

Img

Thermo Scientific

PIPA5104762

--

Img

Thermo Scientific

PIPA5104765

--

Img

Thermo Scientific

PIPA5105237

--

Img

Thermo Scientific

PIPA5104865

--

Img

Thermo Scientific

PIPA5104918

--

Description

  • Antibody detects endogenous levels of ALK only when phosphorylated at Tyrosine 1507
  • Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily
  • It is vital for brain development
  • Mutations, rearrangements, and amplifications in the ALK gene have been found in tumors, including anaplastic large cell lymphoma, neurblastoma, and non-small cell lung cancer
  • Chromosomal rearrangement is the most common genetic alteration
  • The translocation creates a fusion gene consisting of the ALK gene and the nucleophosmin gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5
  • A recent study shows that the product of the NPM-ALK fusion gene is oncogenic
  • The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain
  • These sequences are absent in the product of the transforming NPM-ALK gene
  • ALK shows the greatest sequence similarity to LTK
  • ALK plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105039

--


Antigen:
Phospho-ALK (Tyr1507)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
Alk; ALK tyrosine kinase receptor; ALK/NPM1 fusion gene; anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki1; Anaplastic Lymphoma Kinase p80; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; npm-alk; p80; Tcrz; TFG/ALK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11682, 238

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P97793, Q9UM73

Gene Symbols:
ALK

Immunogen:
A synthesized peptide derived from human ALK(Accession Q9UM73), corresponding to amino acid residues around phosphorylated Tyr1507.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105040

--


Antigen:
Phospho-HDAC5 (Ser259)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HDAC5

Gene Alias:
AI426555; Antigen NY-CO-9; DKFZp779K1053; FLJ90614; HD5; HD7; HD7b; HD9; HDAC; Hdac4; HDAC5; HDAC-5; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDRP; histone deacetylase 4; histone deacetylase 5; histone deacetylase mHDA1; KIAA0600; KIAA0744; mHDA1; mKIAA0600; NY-CO-9

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10014, 15184

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9UQL6, Q9Z2V6

Gene Symbols:
HDAC5

Immunogen:
A synthesized peptide derived from human HDAC5(Accession Q9UQL6), corresponding to amino acid residues around phosphorylated Ser259.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105041

--


Antigen:
Phospho-HDAC5 (Ser498)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HDAC5

Gene Alias:
AI426555; Antigen NY-CO-9; DKFZp779K1053; FLJ90614; HD5; HD7; HD7b; HD9; HDAC; Hdac4; HDAC5; HDAC-5; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDRP; histone deacetylase 4; histone deacetylase 5; histone deacetylase mHDA1; KIAA0600; KIAA0744; mHDA1; mKIAA0600; NY-CO-9

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10014, 15184, 84580

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9UQL6, Q9Z2V6

Gene Symbols:
HDAC5

Immunogen:
A synthesized peptide derived from human HDAC5(Accession Q9UQL6), corresponding to amino acid residues around phosphorylated Ser498.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105042

--


Antigen:
Phospho-CaMKII alpha/beta/delta (Thr305)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CAMK2B

Gene Alias:
[d]-CaMKII; 2810011D23Rik; 8030469K03Rik; alpha CaM kinase II; alpha-CaMKII; Ca++/calmodulin-dependent protein kinase 2 delta subunit; Ca++/calmodulin-dependent protein kinase II beta subunit; Ca++/calmodulin-dependent protein kinase II delta subunit; Ca++/calmodulin-dependent protein kinase II, delta subunit; Ca2+/calmodulin-dependent protein kinase II alpha; Calci; calcium/calmodulin dependent protein kinase II alpha; calcium/calmodulin dependent protein kinase II beta; calcium/calmodulin dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase II alpha; calcium/calmodulin-dependent protein kinase II alpha subunit; calcium/calmodulin-dependent protein kinase II alpha-B subunit; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II delta; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase II, delta; calcium/calmodulin-dependent protein kinase type II alpha chain; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II delta chain; calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type II subunit beta; calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II alpha subunit; CaM kinase II beta subunit; CaM kinase II delta subunit; caM kinase II subunit alpha; CaM kinase II subunit beta; caM kinase II subunit delta; CAM2; CAMK; CaMK II; CAMK1; Camk2; CaMK2 delta; CaMK-2 delta; CaMK2- delta; Camk2a; CaMK-2a; CaMK2-a; Camk2b; Camk2d; CAMK2G; CAMKA; CAMKB; CAMKD; CAMKG; Camki; CaMKII; CAMK-II; CaMK-II alpha subunit; CaMK-II delta subunit; caMK-II subunit alpha; caMK-II subunit beta; caMK-II subunit delta; CaMKIINalpha; caM-kinase II alpha chain; CaM-kinase II beta chain; CaM-kinase II delta chain; Ck2b; KIAA0968; Kiaa4163; mKIAA0968; PK2CDD; PKCCD; proline rich calmodulin-dependent protein kinase; R74975; RATCAMKI

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108058, 12322, 12323, 24245, 24246, 25400, 815, 816, 817

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P08413, P11275, P11798, P15791, P28652, Q13554, Q13557, Q6PHZ2, Q9UQM7

Gene Symbols:
CAMK2A, CAMK2B, CAMK2D

Immunogen:
A synthesized peptide derived from human CAMK2A(Accession Q9UQM7), corresponding to amino acid residues around phosphorylated Thr305.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG