PIPA5105238

Phospho-ALK (Tyr1096) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105238-Each-of-1 In Stock ₹ 44,705.10

PIPA5105238 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-ALK (Tyr1096)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ALK

Gene Alias

Alk; ALK tyrosine kinase receptor; ALK/NPM1 fusion gene; anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki1; Anaplastic Lymphoma Kinase p80; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; npm-alk; p80; Tcrz; TFG/ALK

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11682, 238, 266802

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P97793, Q9UM73

Gene Symbols

ALK

Immunogen

A synthesized peptide derived from human ALK(Accession Q9UM73), corresponding to amino acid residues around phosphorylated Tyr1096.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of ALK only when phosphorylated at Tyr1096
  • Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily
  • It is vital for brain development
  • Mutations, rearrangements, and amplifications in the ALK gene have been found in tumors, including anaplastic large cell lymphoma, neurblastoma, and non-small cell lung cancer
  • Chromosomal rearrangement is the most common genetic alteration
  • The translocation creates a fusion gene consisting of the ALK gene and the nucleophosmin gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5
  • A recent study shows that the product of the NPM-ALK fusion gene is oncogenic
  • The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain
  • These sequences are absent in the product of the transforming NPM-ALK gene
  • ALK shows the greatest sequence similarity to LTK
  • ALK plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105238

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Antigen:
Phospho-ALK (Tyr1096)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
Alk; ALK tyrosine kinase receptor; ALK/NPM1 fusion gene; anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki1; Anaplastic Lymphoma Kinase p80; anaplastic lymphoma receptor tyrosine kinase; CD246; CD246 antigen; EC 2.7.10.1; kinase ALK; mutant anaplastic lymphoma kinase; NBLST3; npm-alk; p80; Tcrz; TFG/ALK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11682, 238, 266802

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P97793, Q9UM73

Gene Symbols:
ALK

Immunogen:
A synthesized peptide derived from human ALK(Accession Q9UM73), corresponding to amino acid residues around phosphorylated Tyr1096.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105240

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Antigen:
Phospho-DAPP1 (Tyr139)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DAPP1

Gene Alias:
b lymphocyte adapter protein Bam32; Bam32; B-cell adapter molecule of 32 kDa; Dapp1; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; dual adaptor for phosphotyrosine and 3-phosphoinositides 1; dual adaptor of phosphotyrosine and 3-phosphoinositides; dual adaptor of phosphotyrosine and 3-phosphoinositides 1; hDAPP1; HSPC066; mDAPP1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27071, 362046

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9UN19

Gene Symbols:
DAPP1

Immunogen:
A synthesized peptide derived from human DAPP1(Accession Q9UN19), corresponding to amino acid residues around phosphorylated Tyr139.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105241

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Antigen:
Phospho-GAB2 (Ser159)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GAB2

Gene Alias:
AI463667; D130058I17Rik; GAB2; Grb2 associated binder 2; GRB2 associated binding protein 2; GRB2-associated binder 2; GRB2-associated binding protein 2; GRB2-associated-binding protein 2; GRB3-3; Growth factor receptor bound protein 2-associated protein 2; KIAA0571; p97; PH domain-containing adaptor molecule p97; pp100

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14389, 84477, 9846

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9EQH1, Q9UQC2, Q9Z1S8

Gene Symbols:
GAB2

Immunogen:
A synthesized peptide derived from human GAB2(Accession Q9UQC2), corresponding to amino acid residues around phosphorylated Ser159.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105242

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Antigen:
Phospho-NUDC (Ser326)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NUDC

Gene Alias:
c15; clone 15; H M NPD011; HNUDC; MNUDC; MNUDC protein; NPD011; nuclear distribution C homolog; nuclear distribution C, dynein complex regulator; nuclear distribution gene C homolog; nuclear distribution gene C homolog (Aspergillus); nuclear distribution protein C homolog; Nuclear migration protein nudC; Nudc; nudC nuclear distribution protein; OTTHUMP00000004405; SIG-92; Silg92; silica-induced gene 92 protein

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10726, 18221, 29648

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O35685, Q63525, Q9Y266

Gene Symbols:
NUDC

Immunogen:
A synthesized peptide derived from human NUDC(Accession Q9Y266), corresponding to amino acid residues around phosphorylated Ser326.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG